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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:79.2 nTPM
HPA:79.2 nTPM
GTEx:83.6 nTPM
FANTOM5:100.6 Scaled Tags Per Million
Pig:54.5 nTPM
Mouse:43.9 nTPM
Allen mouse:0.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 79.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 74.2
2411 Female, age 72, unknown 81.3
1870 Female, age 42, unknown 80.1
1833 Male, age 53, unknown 75.2
1827 Male, age 72, unknown 74.0
1830 Male, age 51, unknown 73.5
2019 Male, age 18, unknown 73.0
2666 Male, age 74, left hemisphere 72.2
2219 Male, age 76, both hemispheres 71.1
2828 Female, age 72, unknown 70.8
2586 Male, age 75, left hemisphere 70.4
Dorsal raphe nucleus
nTPM: 77.8
2298 Female, age 72, unknown 81.6
1828 Male, age 53, unknown 78.2
2750 Male, age 76, both hemispheres 77.6
2047 Male, age 72, unknown 77.3
2016 Female, age 72, unknown 74.3
Inferior colliculus
nTPM: 75.1
2097 Female, age 72, unknown 79.5
1848 Female, age 42, unknown 74.6
1890 Male, age 53, unknown 74.6
2849 Male, age 72, unknown 71.6
Median raphe nucleus
nTPM: 77.9
2220 Male, age 76, midline 77.9
Pedunculopontine tegmental nucleus
nTPM: 77.3
1921 Female, age 85, both hemispheres 79.3
2334 Male, age 80, both hemispheres 78.0
2338 Male, age 61, both hemispheres 74.5
Periaquaductal grey, anterior
nTPM: 74.8
1947 Male, age 18, unknown 76.9
2502 Female, age 75, unknown 74.4
1795 Male, age 51, unknown 73.1
Periaquaductal grey, dorsal
nTPM: 74.9
1840 Male, age 53, unknown 76.0
2464 Female, age 72, unknown 75.2
2850 Male, age 76, both hemispheres 75.1
1831 Male, age 72, unknown 73.1
Periaquaductal grey, lateral
nTPM: 72.8
2053 Male, age 18, unknown 74.0
2140 Male, age 76, both hemispheres 72.3
2272 Male, age 74, both hemispheres 72.0
Pretectal area
nTPM: 75.6
2667 Female, age 75, unknown 80.1
2224 Female, age 72, unknown 79.2
1817 Female, age 42, unknown 77.4
1944 Female, age 72, unknown 76.5
1816 Male, age 51, unknown 76.2
1815 Male, age 53, unknown 75.4
2825 Male, age 18, unknown 75.4
2007 Male, age 72, unknown 75.0
2273 Male, age 74, both hemispheres 74.0
2316 Male, age 76, right hemisphere 73.7
2407 Male, age 75, both hemispheres 68.1
Red nucleus
nTPM: 74.9
1821 Female, age 72, unknown 84.4
1904 Male, age 53, unknown 77.4
1954 Female, age 42, unknown 76.9
2823 Male, age 76, right hemisphere 76.1
1865 Male, age 51, unknown 75.8
2503 Female, age 72, unknown 75.4
2725 Female, age 75, unknown 74.8
2769 Male, age 72, unknown 73.7
2227 Male, age 72, unknown 73.3
2588 Male, age 74, left hemisphere 72.8
2785 Male, age 18, unknown 70.3
2584 Male, age 75, left hemisphere 68.0
Substantia nigra
nTPM: 78.6
2241 Male, age 72, unknown 88.4
1916 Female, age 42, unknown 84.5
1851 Male, age 51, unknown 81.8
2409 Female, age 72, unknown 80.8
1889 Female, age 72, unknown 79.9
2699 Male, age 18, unknown 78.7
1941 Male, age 53, unknown 76.2
2590 Female, age 75, unknown 73.3
2665 Male, age 74, both hemispheres 72.2
2583 Male, age 75, right hemisphere 69.8
Superior colliculus
nTPM: 73.4
1895 Male, age 76, right hemisphere 76.6
2587 Male, age 74, left hemisphere 75.5
2261 Male, age 18, unknown 74.9
1995 Male, age 72, unknown 73.7
2668 Female, age 75, unknown 73.7
1913 Female, age 42, unknown 73.4
1796 Male, age 53, unknown 73.2
2087 Female, age 72, unknown 73.2
1839 Male, age 51, unknown 72.4
2664 Male, age 75, both hemispheres 67.8
Ventral tegmental area
nTPM: 79.2
2410 Female, age 72, unknown 84.9
1915 Female, age 42, unknown 82.1
2218 Male, age 76, both hemispheres 79.9
2223 Female, age 72, unknown 76.7
1942 Male, age 51, unknown 76.5
2021 Male, age 53, unknown 75.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 83.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 83.6
Samples: 139

Max nTPM: 135.5
Min nTPM: 46.8
Std nTPM: 17.0
Median nTPM: 80.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 135.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 122.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 120.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 119.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 118.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 117.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 114.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 114.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 113.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 110.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 108.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 107.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 107.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 107.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 106.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 106.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 106.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 106.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 105.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 104.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 104.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 104.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 104.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 103.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 102.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 101.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 99.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 97.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 97.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 96.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 95.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 95.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 95.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 94.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 94.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 94.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 93.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 93.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 93.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 92.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 91.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 90.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 89.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 89.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 89.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 89.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 89.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 88.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 88.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 88.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 87.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 87.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 87.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 87.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 87.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 86.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 86.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 85.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 84.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 84.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 84.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 83.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 82.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 82.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 82.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 81.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 81.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 81.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 80.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 80.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 80.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 80.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 80.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 80.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 79.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 79.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 79.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 79.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 79.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 79.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 79.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 79.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 77.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 77.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 76.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 76.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 76.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 76.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 76.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 75.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 75.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 75.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 74.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 74.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 74.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 74.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 73.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 73.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 73.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 73.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 72.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 72.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 72.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 72.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 72.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 72.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 71.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 71.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 70.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 69.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 69.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 69.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 69.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 68.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 68.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 67.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 67.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 67.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 67.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 67.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 67.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 66.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 66.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 66.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 66.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 64.1
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 61.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 61.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 61.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 58.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 57.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 57.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 57.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 56.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 52.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 52.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 51.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 49.5
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 46.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 100.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 100.6
FF:10158-103A5 76 years, female 100.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 54.5
Pig sample Sample description nTPM
Midbrain
nTPM: 54.5
Samples: 4

Max nTPM: 66.9
Min nTPM: 43.2
Sample A Female 43.2
Sample B Female 47.8
Sample C Male 66.9
Sample D Male 60.1
Periaqueductal gray
nTPM: 42.8
Samples: 3

Max nTPM: 45.2
Min nTPM: 40.3
Sample B Female 42.8
Sample C Male 45.2
Sample D Male 40.3
Substantia nigra
nTPM: 50.4
Samples: 4

Max nTPM: 62.9
Min nTPM: 36.0
Sample A Female 62.9
Sample B Female 43.9
Sample C Male 58.6
Sample D Male 36.0
Superior colliculi
nTPM: 53.7
Samples: 4

Max nTPM: 64.3
Min nTPM: 40.0
Sample A Female 57.1
Sample B Female 40.0
Sample C Male 64.3
Sample D Male 53.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 43.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 43.9
Samples: 4

Max nTPM: 45.6
Min nTPM: 41.4
Sample A Male 41.4
Sample B Male 44.7
Sample C Female 45.6
Sample D Female 44.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.4
71493129 Antisense, RP_050913_02_C01, Mouse strain C57BL/6J (56 days, male) 0.4

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