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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:109.4 nTPM
HPA:109.4 nTPM
GTEx:100.1 nTPM
FANTOM5:84.6 Scaled Tags Per Million
Pig:55.1 nTPM
Mouse:123.4 nTPM
Allen mouse:15.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 109.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 103.5
2411 Female, age 72, unknown 109.2
1870 Female, age 42, unknown 106.8
2219 Male, age 76, both hemispheres 106.7
2019 Male, age 18, unknown 106.6
1827 Male, age 72, unknown 105.3
1833 Male, age 53, unknown 102.9
2828 Female, age 72, unknown 100.9
1830 Male, age 51, unknown 100.7
2666 Male, age 74, left hemisphere 98.7
2586 Male, age 75, left hemisphere 97.3
Dorsal raphe nucleus
nTPM: 106.8
2298 Female, age 72, unknown 116.0
2047 Male, age 72, unknown 107.4
2750 Male, age 76, both hemispheres 106.4
1828 Male, age 53, unknown 103.3
2016 Female, age 72, unknown 101.2
Inferior colliculus
nTPM: 103.4
1848 Female, age 42, unknown 104.8
2097 Female, age 72, unknown 104.1
1890 Male, age 53, unknown 102.7
2849 Male, age 72, unknown 102.1
Median raphe nucleus
nTPM: 105.7
2220 Male, age 76, midline 105.7
Pedunculopontine tegmental nucleus
nTPM: 107.1
2334 Male, age 80, both hemispheres 109.8
1921 Female, age 85, both hemispheres 106.4
2338 Male, age 61, both hemispheres 105.2
Periaquaductal grey, anterior
nTPM: 102.1
2502 Female, age 75, unknown 103.4
1795 Male, age 51, unknown 101.6
1947 Male, age 18, unknown 101.3
Periaquaductal grey, dorsal
nTPM: 102.3
1840 Male, age 53, unknown 106.4
2850 Male, age 76, both hemispheres 102.8
2464 Female, age 72, unknown 100.2
1831 Male, age 72, unknown 100.0
Periaquaductal grey, lateral
nTPM: 102.4
2272 Male, age 74, both hemispheres 106.4
2053 Male, age 18, unknown 101.5
2140 Male, age 76, both hemispheres 99.3
Pretectal area
nTPM: 105.4
2007 Male, age 72, unknown 110.0
1817 Female, age 42, unknown 109.9
1816 Male, age 51, unknown 109.5
2273 Male, age 74, both hemispheres 108.5
1944 Female, age 72, unknown 107.4
2224 Female, age 72, unknown 106.1
1815 Male, age 53, unknown 106.0
2667 Female, age 75, unknown 104.8
2825 Male, age 18, unknown 102.0
2316 Male, age 76, right hemisphere 98.0
2407 Male, age 75, both hemispheres 96.9
Red nucleus
nTPM: 104.0
1821 Female, age 72, unknown 113.7
2725 Female, age 75, unknown 109.1
2785 Male, age 18, unknown 105.6
2503 Female, age 72, unknown 105.4
1954 Female, age 42, unknown 104.7
1904 Male, age 53, unknown 104.0
2769 Male, age 72, unknown 103.1
2227 Male, age 72, unknown 102.3
2588 Male, age 74, left hemisphere 102.3
1865 Male, age 51, unknown 102.2
2823 Male, age 76, right hemisphere 101.5
2584 Male, age 75, left hemisphere 94.5
Substantia nigra
nTPM: 109.4
1916 Female, age 42, unknown 120.7
1851 Male, age 51, unknown 114.0
1889 Female, age 72, unknown 112.6
2241 Male, age 72, unknown 110.7
2409 Female, age 72, unknown 110.3
1941 Male, age 53, unknown 110.1
2699 Male, age 18, unknown 106.0
2665 Male, age 74, both hemispheres 105.3
2590 Female, age 75, unknown 104.6
2583 Male, age 75, right hemisphere 99.6
Superior colliculus
nTPM: 102.0
2587 Male, age 74, left hemisphere 108.3
1796 Male, age 53, unknown 106.7
1895 Male, age 76, right hemisphere 105.3
2261 Male, age 18, unknown 104.2
1839 Male, age 51, unknown 103.3
2087 Female, age 72, unknown 102.0
1913 Female, age 42, unknown 100.4
2668 Female, age 75, unknown 99.8
1995 Male, age 72, unknown 99.2
2664 Male, age 75, both hemispheres 90.5
Ventral tegmental area
nTPM: 106.3
2410 Female, age 72, unknown 113.6
1915 Female, age 42, unknown 112.9
2218 Male, age 76, both hemispheres 107.5
2223 Female, age 72, unknown 103.5
1942 Male, age 51, unknown 101.0
2021 Male, age 53, unknown 99.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 100.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 100.1
Samples: 139

Max nTPM: 155.0
Min nTPM: 65.5
Std nTPM: 19.1
Median nTPM: 96.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 155.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 154.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 154.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 153.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 150.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 147.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 146.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 141.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 141.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 138.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 135.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 134.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 133.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 127.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 126.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 125.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 122.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 122.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 120.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 119.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 119.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 118.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 117.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 113.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 111.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 111.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 111.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 111.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 110.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 110.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 110.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 110.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 110.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 109.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 109.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 108.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 108.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 107.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 107.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 107.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 107.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 106.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 106.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 106.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 105.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 105.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 104.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 104.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 102.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 102.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 102.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 102.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 101.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 99.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 99.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 99.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 99.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 99.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 98.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 98.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 98.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 97.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 97.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 97.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 97.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 97.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 96.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 96.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 96.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 96.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 96.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 95.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 95.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 94.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 94.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 94.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 94.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 94.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 93.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 93.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 93.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 92.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 92.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 91.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 91.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 91.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 90.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 90.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 89.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 89.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 89.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 89.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 89.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 88.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 88.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 88.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 88.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 88.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 87.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 87.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 87.5
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 87.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 87.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 86.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 86.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 86.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 86.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 86.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 85.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 85.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 85.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 85.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 84.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 84.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 84.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 83.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 83.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 83.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 83.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 82.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 82.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 81.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 81.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 81.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 81.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 80.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 79.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 79.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 78.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 78.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 78.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 77.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 76.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 76.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 75.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 75.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 74.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 66.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 65.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 84.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 84.6
FF:10158-103A5 76 years, female 84.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 55.1
Pig sample Sample description nTPM
Midbrain
nTPM: 55.1
Samples: 4

Max nTPM: 70.4
Min nTPM: 47.4
Sample A Female 70.4
Sample B Female 50.1
Sample C Male 52.4
Sample D Male 47.4
Periaqueductal gray
nTPM: 44.8
Samples: 3

Max nTPM: 51.7
Min nTPM: 39.8
Sample B Female 42.9
Sample C Male 51.7
Sample D Male 39.8
Substantia nigra
nTPM: 53.4
Samples: 4

Max nTPM: 69.1
Min nTPM: 43.6
Sample A Female 69.1
Sample B Female 44.3
Sample C Male 56.7
Sample D Male 43.6
Superior colliculi
nTPM: 54.6
Samples: 4

Max nTPM: 60.9
Min nTPM: 50.4
Sample A Female 60.9
Sample B Female 52.2
Sample C Male 54.8
Sample D Male 50.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 123.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 123.4
Samples: 4

Max nTPM: 148.1
Min nTPM: 105.7
Sample A Male 148.1
Sample B Male 126.9
Sample C Female 113.0
Sample D Female 105.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 15.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 15.7
81600108 Antisense, RP_080205_02_D01, Mouse strain C57BL/6J (56 days, male) 17.3
413791 Antisense, RP_040809_01_E01, Mouse strain C57BL/6J (56 days, male) 14.2

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