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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN OVARY
PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:960.3 nTPM
HPA:960.3 nTPM
GTEx:763.8 nTPM
FANTOM5:553.8 Scaled Tags Per Million
Pig:381.1 nTPM
Mouse:354.2 nTPM
Allen mouse:20.3 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 960.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 845.1
2586 Male, age 75, left hemisphere 1076.8
2828 Female, age 72, unknown 984.7
1827 Male, age 72, unknown 913.8
2666 Male, age 74, left hemisphere 873.0
1870 Female, age 42, unknown 855.6
2219 Male, age 76, both hemispheres 847.8
1833 Male, age 53, unknown 782.1
2411 Female, age 72, unknown 762.9
1830 Male, age 51, unknown 732.7
2019 Male, age 18, unknown 621.6
Dorsal raphe nucleus
nTPM: 883.6
2016 Female, age 72, unknown 966.5
2047 Male, age 72, unknown 964.2
2298 Female, age 72, unknown 902.7
1828 Male, age 53, unknown 850.8
2750 Male, age 76, both hemispheres 734.0
Inferior colliculus
nTPM: 944.1
2849 Male, age 72, unknown 993.1
1848 Female, age 42, unknown 960.6
1890 Male, age 53, unknown 924.0
2097 Female, age 72, unknown 898.7
Median raphe nucleus
nTPM: 766.0
2220 Male, age 76, midline 766.0
Pedunculopontine tegmental nucleus
nTPM: 749.5
1921 Female, age 85, both hemispheres 786.9
2334 Male, age 80, both hemispheres 734.7
2338 Male, age 61, both hemispheres 726.8
Periaquaductal grey, anterior
nTPM: 892.3
1795 Male, age 51, unknown 979.7
1947 Male, age 18, unknown 883.4
2502 Female, age 75, unknown 813.9
Periaquaductal grey, dorsal
nTPM: 960.3
1840 Male, age 53, unknown 1122.0
1831 Male, age 72, unknown 959.6
2850 Male, age 76, both hemispheres 906.0
2464 Female, age 72, unknown 853.5
Periaquaductal grey, lateral
nTPM: 938.0
2053 Male, age 18, unknown 1064.2
2140 Male, age 76, both hemispheres 890.0
2272 Male, age 74, both hemispheres 860.0
Pretectal area
nTPM: 828.1
2825 Male, age 18, unknown 1010.2
2224 Female, age 72, unknown 944.1
1944 Female, age 72, unknown 865.7
1816 Male, age 51, unknown 845.9
2667 Female, age 75, unknown 839.4
2273 Male, age 74, both hemispheres 801.7
1817 Female, age 42, unknown 794.2
1815 Male, age 53, unknown 784.2
2407 Male, age 75, both hemispheres 781.0
2316 Male, age 76, right hemisphere 756.4
2007 Male, age 72, unknown 686.6
Red nucleus
nTPM: 738.7
2725 Female, age 75, unknown 853.6
2503 Female, age 72, unknown 819.8
2769 Male, age 72, unknown 780.7
2227 Male, age 72, unknown 778.4
2588 Male, age 74, left hemisphere 745.0
1821 Female, age 72, unknown 744.2
2584 Male, age 75, left hemisphere 733.6
1954 Female, age 42, unknown 724.8
2823 Male, age 76, right hemisphere 701.6
1904 Male, age 53, unknown 685.0
1865 Male, age 51, unknown 669.3
2785 Male, age 18, unknown 628.2
Substantia nigra
nTPM: 848.8
2699 Male, age 18, unknown 1089.6
1916 Female, age 42, unknown 933.6
2665 Male, age 74, both hemispheres 881.3
1851 Male, age 51, unknown 867.4
2583 Male, age 75, right hemisphere 848.2
2590 Female, age 75, unknown 798.8
1889 Female, age 72, unknown 798.4
1941 Male, age 53, unknown 792.5
2241 Male, age 72, unknown 773.1
2409 Female, age 72, unknown 705.6
Superior colliculus
nTPM: 852.5
2664 Male, age 75, both hemispheres 1040.3
1796 Male, age 53, unknown 946.1
1839 Male, age 51, unknown 891.6
2261 Male, age 18, unknown 882.0
2087 Female, age 72, unknown 852.7
1913 Female, age 42, unknown 818.6
2668 Female, age 75, unknown 797.0
2587 Male, age 74, left hemisphere 795.4
1995 Male, age 72, unknown 769.4
1895 Male, age 76, right hemisphere 732.2
Ventral tegmental area
nTPM: 843.4
1915 Female, age 42, unknown 926.2
2021 Male, age 53, unknown 878.2
1942 Male, age 51, unknown 872.4
2218 Male, age 76, both hemispheres 819.0
2223 Female, age 72, unknown 785.5
2410 Female, age 72, unknown 779.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 763.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 763.8
Samples: 139

Max nTPM: 2091.0
Min nTPM: 99.9
Std nTPM: 361.9
Median nTPM: 739.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 2091.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1946.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1744.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1589.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1582.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1516.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1438.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1434.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 1396.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1387.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1377.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1366.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1274.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1256.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1229.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1226.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1223.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1167.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1129.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1114.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1111.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 1108.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 1061.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1026.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1025.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 1016.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 999.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 985.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 981.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 975.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 967.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 954.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 951.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 940.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 931.6
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 920.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 919.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 918.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 916.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 912.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 911.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 901.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 901.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 888.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 886.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 882.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 878.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 864.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 862.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 857.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 843.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 838.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 829.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 824.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 823.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 818.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 813.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 810.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 808.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 805.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 803.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 796.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 787.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 780.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 774.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 771.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 770.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 750.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 743.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 739.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 735.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 723.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 700.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 696.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 680.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 672.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 672.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 664.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 650.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 630.2
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 628.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 622.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 615.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 607.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 604.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 597.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 590.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 584.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 583.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 579.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 579.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 576.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 572.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 571.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 570.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 562.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 547.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 545.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 543.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 542.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 535.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 528.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 527.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 512.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 502.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 501.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 497.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 495.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 478.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 474.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 466.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 450.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 448.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 434.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 432.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 431.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 429.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 422.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 422.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 415.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 415.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 411.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 369.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 344.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 320.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 317.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 316.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 314.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 313.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 300.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 285.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 278.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 274.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 258.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 251.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 209.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 193.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 151.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 99.9
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 553.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 553.8
FF:10158-103A5 76 years, female 553.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 381.1
Pig sample Sample description nTPM
Midbrain
nTPM: 381.1
Samples: 4

Max nTPM: 524.8
Min nTPM: 214.4
Sample A Female 487.8
Sample B Female 214.4
Sample C Male 524.8
Sample D Male 297.4
Periaqueductal gray
nTPM: 269.1
Samples: 3

Max nTPM: 327.0
Min nTPM: 230.2
Sample B Female 230.2
Sample C Male 327.0
Sample D Male 250.0
Substantia nigra
nTPM: 313.1
Samples: 4

Max nTPM: 410.8
Min nTPM: 245.3
Sample A Female 410.8
Sample B Female 284.7
Sample C Male 311.5
Sample D Male 245.3
Superior colliculi
nTPM: 350.6
Samples: 4

Max nTPM: 435.1
Min nTPM: 301.4
Sample A Female 358.3
Sample B Female 307.5
Sample C Male 435.1
Sample D Male 301.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 354.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 354.2
Samples: 4

Max nTPM: 384.0
Min nTPM: 332.6
Sample A Male 384.0
Sample B Male 339.2
Sample C Female 332.6
Sample D Female 361.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 20.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 20.3
67936207 Antisense, RP_040928_01_A06, Mouse strain C57BL/6J (56 days, male) 24.3
68196976 Antisense, RP_040928_01_A06, Mouse strain C57BL/6J (56 days, male) 19.9
77414652 Antisense, RP_070205_01_H10, Mouse strain C57BL/6J (56 days, male) 16.3

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