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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:62.8 nTPM
HPA:62.8 nTPM
GTEx:83.5 nTPM
FANTOM5:40.1 Scaled Tags Per Million
Pig:15.6 nTPM
Mouse:40.3 nTPM
Allen mouse:2.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 62.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 60.5
2586 Male, age 75, left hemisphere 77.3
2019 Male, age 18, unknown 65.3
2666 Male, age 74, left hemisphere 65.3
2219 Male, age 76, both hemispheres 62.9
2828 Female, age 72, unknown 58.0
2411 Female, age 72, unknown 57.4
1827 Male, age 72, unknown 56.8
1870 Female, age 42, unknown 56.0
1833 Male, age 53, unknown 53.5
1830 Male, age 51, unknown 53.0
Dorsal raphe nucleus
nTPM: 58.1
1828 Male, age 53, unknown 63.3
2047 Male, age 72, unknown 59.5
2750 Male, age 76, both hemispheres 58.0
2298 Female, age 72, unknown 57.5
2016 Female, age 72, unknown 52.5
Inferior colliculus
nTPM: 57.5
2097 Female, age 72, unknown 60.1
1890 Male, age 53, unknown 59.6
1848 Female, age 42, unknown 55.8
2849 Male, age 72, unknown 54.4
Median raphe nucleus
nTPM: 61.8
2220 Male, age 76, midline 61.8
Pedunculopontine tegmental nucleus
nTPM: 58.9
2334 Male, age 80, both hemispheres 61.8
1921 Female, age 85, both hemispheres 59.8
2338 Male, age 61, both hemispheres 55.1
Periaquaductal grey, anterior
nTPM: 57.7
1795 Male, age 51, unknown 58.8
2502 Female, age 75, unknown 58.0
1947 Male, age 18, unknown 56.4
Periaquaductal grey, dorsal
nTPM: 52.9
1840 Male, age 53, unknown 56.4
1831 Male, age 72, unknown 52.8
2464 Female, age 72, unknown 52.3
2850 Male, age 76, both hemispheres 50.2
Periaquaductal grey, lateral
nTPM: 48.6
2140 Male, age 76, both hemispheres 48.9
2053 Male, age 18, unknown 48.6
2272 Male, age 74, both hemispheres 48.4
Pretectal area
nTPM: 60.3
2007 Male, age 72, unknown 77.4
1817 Female, age 42, unknown 73.4
1944 Female, age 72, unknown 73.1
1816 Male, age 51, unknown 70.2
1815 Male, age 53, unknown 60.8
2667 Female, age 75, unknown 55.8
2407 Male, age 75, both hemispheres 54.2
2825 Male, age 18, unknown 51.9
2224 Female, age 72, unknown 50.7
2273 Male, age 74, both hemispheres 48.6
2316 Male, age 76, right hemisphere 47.3
Red nucleus
nTPM: 58.0
2785 Male, age 18, unknown 67.5
2588 Male, age 74, left hemisphere 61.4
2584 Male, age 75, left hemisphere 59.4
1821 Female, age 72, unknown 58.9
2769 Male, age 72, unknown 58.7
2725 Female, age 75, unknown 58.0
1954 Female, age 42, unknown 57.5
2503 Female, age 72, unknown 57.3
2227 Male, age 72, unknown 56.6
1865 Male, age 51, unknown 55.8
1904 Male, age 53, unknown 53.4
2823 Male, age 76, right hemisphere 51.9
Substantia nigra
nTPM: 62.8
1916 Female, age 42, unknown 70.8
2665 Male, age 74, both hemispheres 70.7
1889 Female, age 72, unknown 67.0
1851 Male, age 51, unknown 66.1
1941 Male, age 53, unknown 63.4
2583 Male, age 75, right hemisphere 63.1
2590 Female, age 75, unknown 57.1
2699 Male, age 18, unknown 57.0
2241 Male, age 72, unknown 56.9
2409 Female, age 72, unknown 56.0
Superior colliculus
nTPM: 57.2
2087 Female, age 72, unknown 65.3
2668 Female, age 75, unknown 64.0
2664 Male, age 75, both hemispheres 61.3
1796 Male, age 53, unknown 57.8
2261 Male, age 18, unknown 57.2
1913 Female, age 42, unknown 55.6
1895 Male, age 76, right hemisphere 54.1
1995 Male, age 72, unknown 53.2
1839 Male, age 51, unknown 53.1
2587 Male, age 74, left hemisphere 50.7
Ventral tegmental area
nTPM: 60.1
1915 Female, age 42, unknown 63.4
2218 Male, age 76, both hemispheres 63.1
2410 Female, age 72, unknown 62.8
1942 Male, age 51, unknown 59.6
2223 Female, age 72, unknown 56.2
2021 Male, age 53, unknown 55.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 83.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 83.5
Samples: 139

Max nTPM: 180.8
Min nTPM: 30.7
Std nTPM: 27.5
Median nTPM: 80.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 180.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 159.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 151.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 143.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 140.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 136.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 134.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 132.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 132.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 129.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 128.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 125.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 125.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 121.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 120.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 120.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 119.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 118.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 118.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 115.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 114.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 110.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 110.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 110.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 107.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 106.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 106.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 105.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 105.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 105.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 103.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 102.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 101.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 101.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 101.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 101.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 100.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 99.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 96.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 96.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 95.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 94.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 93.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 93.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 91.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 90.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 89.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 89.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 89.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 89.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 89.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 88.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 88.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 87.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 86.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 86.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 86.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 85.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 84.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 83.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 83.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 82.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 82.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 82.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 82.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 81.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 81.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 81.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 80.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 80.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 79.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 79.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 78.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 78.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 78.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 78.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 77.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 77.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 77.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 76.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 76.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 76.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 74.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 73.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 72.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 72.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 72.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 72.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 72.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 71.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 71.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 70.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 69.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 69.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 69.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 69.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 68.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 65.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 65.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 63.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 63.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 63.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 62.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 62.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 61.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 61.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 61.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 60.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 59.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 58.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 57.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 57.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 57.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 56.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 56.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 56.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 55.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 55.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 54.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 54.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 53.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 52.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 52.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 52.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 51.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 50.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 50.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 49.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 49.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 49.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 48.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 48.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 47.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 46.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 45.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 41.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 39.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 38.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 30.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 40.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 40.1
FF:10158-103A5 76 years, female 40.1

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 15.6
Pig sample Sample description nTPM
Midbrain
nTPM: 14.2
Samples: 4

Max nTPM: 17.3
Min nTPM: 12.4
Sample A Female 13.4
Sample B Female 12.4
Sample C Male 17.3
Sample D Male 13.7
Periaqueductal gray
nTPM: 10.9
Samples: 3

Max nTPM: 11.9
Min nTPM: 9.2
Sample B Female 11.7
Sample C Male 11.9
Sample D Male 9.2
Substantia nigra
nTPM: 14.1
Samples: 4

Max nTPM: 15.8
Min nTPM: 12.2
Sample A Female 15.3
Sample B Female 13.2
Sample C Male 15.8
Sample D Male 12.2
Superior colliculi
nTPM: 15.6
Samples: 4

Max nTPM: 19.6
Min nTPM: 12.4
Sample A Female 16.2
Sample B Female 12.4
Sample C Male 19.6
Sample D Male 14.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 40.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 40.3
Samples: 4

Max nTPM: 42.6
Min nTPM: 36.8
Sample A Male 42.6
Sample B Male 39.3
Sample C Female 36.8
Sample D Female 42.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.4
71608344 Antisense, RP_050927_01_D12, Mouse strain C57BL/6J (56 days, male) 2.4

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