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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:194.8 nTPM
HPA:194.8 nTPM
GTEx:194.3 nTPM
FANTOM5:361.7 Scaled Tags Per Million
Pig:166.3 nTPM
Mouse:180.2 nTPM
Allen mouse:16.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 194.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 176.1
2586 Male, age 75, left hemisphere 215.9
1830 Male, age 51, unknown 185.9
2411 Female, age 72, unknown 182.9
1833 Male, age 53, unknown 180.0
2666 Male, age 74, left hemisphere 178.5
1870 Female, age 42, unknown 171.9
2019 Male, age 18, unknown 171.6
2828 Female, age 72, unknown 171.3
1827 Male, age 72, unknown 162.6
2219 Male, age 76, both hemispheres 140.9
Dorsal raphe nucleus
nTPM: 144.2
2750 Male, age 76, both hemispheres 185.2
1828 Male, age 53, unknown 143.1
2016 Female, age 72, unknown 137.9
2047 Male, age 72, unknown 128.7
2298 Female, age 72, unknown 126.2
Inferior colliculus
nTPM: 142.0
2849 Male, age 72, unknown 147.7
1890 Male, age 53, unknown 143.2
1848 Female, age 42, unknown 140.1
2097 Female, age 72, unknown 137.1
Median raphe nucleus
nTPM: 133.1
2220 Male, age 76, midline 133.1
Pedunculopontine tegmental nucleus
nTPM: 150.1
2334 Male, age 80, both hemispheres 156.3
2338 Male, age 61, both hemispheres 147.7
1921 Female, age 85, both hemispheres 146.2
Periaquaductal grey, anterior
nTPM: 147.1
1947 Male, age 18, unknown 153.6
1795 Male, age 51, unknown 145.2
2502 Female, age 75, unknown 142.4
Periaquaductal grey, dorsal
nTPM: 129.1
2464 Female, age 72, unknown 154.7
1831 Male, age 72, unknown 137.0
1840 Male, age 53, unknown 120.6
2850 Male, age 76, both hemispheres 104.0
Periaquaductal grey, lateral
nTPM: 131.9
2272 Male, age 74, both hemispheres 140.5
2053 Male, age 18, unknown 140.4
2140 Male, age 76, both hemispheres 115.0
Pretectal area
nTPM: 155.3
2407 Male, age 75, both hemispheres 185.4
2316 Male, age 76, right hemisphere 179.1
1815 Male, age 53, unknown 176.0
2007 Male, age 72, unknown 170.7
1817 Female, age 42, unknown 159.1
2825 Male, age 18, unknown 151.4
1816 Male, age 51, unknown 149.3
1944 Female, age 72, unknown 145.4
2667 Female, age 75, unknown 134.7
2224 Female, age 72, unknown 131.1
2273 Male, age 74, both hemispheres 126.5
Red nucleus
nTPM: 194.8
2823 Male, age 76, right hemisphere 211.9
1904 Male, age 53, unknown 209.9
2503 Female, age 72, unknown 207.6
2584 Male, age 75, left hemisphere 205.0
1865 Male, age 51, unknown 203.1
2227 Male, age 72, unknown 194.8
2785 Male, age 18, unknown 194.2
2588 Male, age 74, left hemisphere 192.3
2769 Male, age 72, unknown 191.1
2725 Female, age 75, unknown 179.6
1821 Female, age 72, unknown 175.9
1954 Female, age 42, unknown 172.9
Substantia nigra
nTPM: 163.5
2583 Male, age 75, right hemisphere 198.3
2590 Female, age 75, unknown 190.5
1851 Male, age 51, unknown 168.4
2409 Female, age 72, unknown 162.7
2665 Male, age 74, both hemispheres 159.3
1889 Female, age 72, unknown 158.5
2699 Male, age 18, unknown 157.4
1916 Female, age 42, unknown 154.9
1941 Male, age 53, unknown 149.1
2241 Male, age 72, unknown 136.1
Superior colliculus
nTPM: 173.2
1995 Male, age 72, unknown 198.6
1913 Female, age 42, unknown 194.0
2668 Female, age 75, unknown 189.7
1895 Male, age 76, right hemisphere 188.0
1796 Male, age 53, unknown 167.9
2664 Male, age 75, both hemispheres 164.6
1839 Male, age 51, unknown 161.4
2261 Male, age 18, unknown 160.8
2587 Male, age 74, left hemisphere 159.1
2087 Female, age 72, unknown 148.3
Ventral tegmental area
nTPM: 152.7
2410 Female, age 72, unknown 176.8
2223 Female, age 72, unknown 154.2
1915 Female, age 42, unknown 153.5
1942 Male, age 51, unknown 147.2
2218 Male, age 76, both hemispheres 144.0
2021 Male, age 53, unknown 140.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 194.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 194.3
Samples: 139

Max nTPM: 518.0
Min nTPM: 86.2
Std nTPM: 73.4
Median nTPM: 179.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 518.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 488.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 481.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 430.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 370.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 370.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 348.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 311.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 299.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 295.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 293.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 285.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 282.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 278.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 277.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 276.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 273.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 271.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 254.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 253.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 250.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 249.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 246.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 244.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 244.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 239.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 237.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 234.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 229.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 222.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 221.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 220.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 219.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 219.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 216.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 216.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 212.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 211.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 211.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 210.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 209.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 207.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 206.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 206.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 205.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 201.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 200.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 197.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 195.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 194.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 193.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 192.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 192.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 191.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 191.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 190.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 189.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 189.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 187.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 187.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 186.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 184.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 184.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 183.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 182.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 182.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 182.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 182.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 180.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 179.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 179.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 178.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 177.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 176.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 175.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 175.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 175.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 174.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 174.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 173.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 172.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 171.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 171.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 170.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 170.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 169.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 168.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 167.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 165.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 164.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 164.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 158.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 158.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 158.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 157.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 156.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 154.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 154.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 153.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 152.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 151.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 149.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 149.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 149.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 149.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 148.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 147.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 145.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 144.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 143.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 140.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 139.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 137.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 136.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 134.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 134.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 133.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 133.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 133.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 131.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 130.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 129.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 129.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 129.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 127.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 125.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 121.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 119.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 118.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 115.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 112.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 112.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 111.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 108.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 107.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 100.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 97.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 90.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 86.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 361.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 361.7
FF:10158-103A5 76 years, female 361.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 166.3
Pig sample Sample description nTPM
Midbrain
nTPM: 166.3
Samples: 4

Max nTPM: 244.0
Min nTPM: 125.1
Sample A Female 244.0
Sample B Female 163.1
Sample C Male 132.9
Sample D Male 125.1
Periaqueductal gray
nTPM: 125.6
Samples: 3

Max nTPM: 134.8
Min nTPM: 119.3
Sample B Female 134.8
Sample C Male 119.3
Sample D Male 122.8
Substantia nigra
nTPM: 165.4
Samples: 4

Max nTPM: 233.4
Min nTPM: 111.1
Sample A Female 161.2
Sample B Female 111.1
Sample C Male 155.8
Sample D Male 233.4
Superior colliculi
nTPM: 143.2
Samples: 4

Max nTPM: 171.7
Min nTPM: 87.7
Sample A Female 143.4
Sample B Female 87.7
Sample C Male 169.9
Sample D Male 171.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 180.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 180.2
Samples: 4

Max nTPM: 189.4
Min nTPM: 169.7
Sample A Male 189.4
Sample B Male 169.7
Sample C Female 181.2
Sample D Female 180.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 16.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 16.4
69529292 Antisense, RP_050421_03_H11, Mouse strain C57BL/6J (56 days, male) 16.4

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