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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:97.2 nTPM
HPA:97.2 nTPM
GTEx:104.6 nTPM
FANTOM5:51.5 Scaled Tags Per Million
Pig:56.8 nTPM
Mouse:100.7 nTPM
Allen mouse:8.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 97.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 90.1
2411 Female, age 72, unknown 94.8
1827 Male, age 72, unknown 94.6
2586 Male, age 75, left hemisphere 92.5
1870 Female, age 42, unknown 91.8
2019 Male, age 18, unknown 91.3
2219 Male, age 76, both hemispheres 90.7
2828 Female, age 72, unknown 87.7
1833 Male, age 53, unknown 87.4
1830 Male, age 51, unknown 85.3
2666 Male, age 74, left hemisphere 84.8
Dorsal raphe nucleus
nTPM: 94.2
2298 Female, age 72, unknown 102.0
2047 Male, age 72, unknown 99.3
2750 Male, age 76, both hemispheres 92.4
1828 Male, age 53, unknown 91.9
2016 Female, age 72, unknown 85.5
Inferior colliculus
nTPM: 90.8
2097 Female, age 72, unknown 94.6
1890 Male, age 53, unknown 91.2
1848 Female, age 42, unknown 90.0
2849 Male, age 72, unknown 87.7
Median raphe nucleus
nTPM: 94.5
2220 Male, age 76, midline 94.5
Pedunculopontine tegmental nucleus
nTPM: 91.9
1921 Female, age 85, both hemispheres 96.0
2334 Male, age 80, both hemispheres 94.6
2338 Male, age 61, both hemispheres 85.0
Periaquaductal grey, anterior
nTPM: 92.2
1947 Male, age 18, unknown 94.5
1795 Male, age 51, unknown 92.1
2502 Female, age 75, unknown 90.1
Periaquaductal grey, dorsal
nTPM: 88.2
1840 Male, age 53, unknown 91.6
2464 Female, age 72, unknown 88.0
1831 Male, age 72, unknown 86.8
2850 Male, age 76, both hemispheres 86.3
Periaquaductal grey, lateral
nTPM: 86.6
2272 Male, age 74, both hemispheres 89.4
2053 Male, age 18, unknown 86.8
2140 Male, age 76, both hemispheres 83.5
Pretectal area
nTPM: 93.0
1816 Male, age 51, unknown 99.1
2007 Male, age 72, unknown 97.8
1817 Female, age 42, unknown 96.2
2667 Female, age 75, unknown 95.3
1944 Female, age 72, unknown 95.2
2224 Female, age 72, unknown 94.6
1815 Male, age 53, unknown 92.2
2273 Male, age 74, both hemispheres 92.2
2825 Male, age 18, unknown 90.6
2407 Male, age 75, both hemispheres 86.1
2316 Male, age 76, right hemisphere 84.1
Red nucleus
nTPM: 89.4
1821 Female, age 72, unknown 98.2
1904 Male, age 53, unknown 90.7
2584 Male, age 75, left hemisphere 89.4
2785 Male, age 18, unknown 89.2
1865 Male, age 51, unknown 89.0
2725 Female, age 75, unknown 88.7
2769 Male, age 72, unknown 88.7
2503 Female, age 72, unknown 88.5
2227 Male, age 72, unknown 88.4
2588 Male, age 74, left hemisphere 88.4
1954 Female, age 42, unknown 88.2
2823 Male, age 76, right hemisphere 85.9
Substantia nigra
nTPM: 97.2
1851 Male, age 51, unknown 104.7
1916 Female, age 42, unknown 103.7
1941 Male, age 53, unknown 99.2
1889 Female, age 72, unknown 98.4
2409 Female, age 72, unknown 98.3
2665 Male, age 74, both hemispheres 95.9
2241 Male, age 72, unknown 95.6
2699 Male, age 18, unknown 93.0
2590 Female, age 75, unknown 92.2
2583 Male, age 75, right hemisphere 91.6
Superior colliculus
nTPM: 90.4
2668 Female, age 75, unknown 95.1
1796 Male, age 53, unknown 93.1
1895 Male, age 76, right hemisphere 92.7
2261 Male, age 18, unknown 92.0
2587 Male, age 74, left hemisphere 91.8
2087 Female, age 72, unknown 90.8
2664 Male, age 75, both hemispheres 88.5
1839 Male, age 51, unknown 87.7
1913 Female, age 42, unknown 87.4
1995 Male, age 72, unknown 84.8
Ventral tegmental area
nTPM: 95.2
2410 Female, age 72, unknown 103.5
1915 Female, age 42, unknown 99.4
2218 Male, age 76, both hemispheres 95.1
2223 Female, age 72, unknown 92.4
1942 Male, age 51, unknown 91.5
2021 Male, age 53, unknown 89.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 104.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 104.6
Samples: 139

Max nTPM: 204.5
Min nTPM: 55.7
Std nTPM: 28.8
Median nTPM: 99.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 204.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 188.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 180.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 180.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 179.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 172.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 169.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 163.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 162.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 160.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 152.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 151.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 147.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 146.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 145.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 141.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 138.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 137.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 136.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 136.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 135.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 133.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 131.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 131.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 130.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 128.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 124.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 123.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 123.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 122.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 121.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 121.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 121.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 120.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 119.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 118.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 117.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 117.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 115.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 113.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 112.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 111.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 111.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 109.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 109.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 108.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 108.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 108.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 106.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 105.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 104.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 104.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 104.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 103.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 103.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 103.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 103.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 102.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 102.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 102.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 102.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 102.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 102.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 102.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 101.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 101.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 100.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 100.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 99.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 99.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 99.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 97.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 97.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 97.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 96.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 95.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 95.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 94.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 94.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 94.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 93.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 93.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 93.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 93.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 92.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 91.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 91.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 90.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 90.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 90.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 89.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 89.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 89.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 88.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 88.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 87.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 87.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 87.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 87.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 86.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 86.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 85.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 84.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 84.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 83.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 83.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 83.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 82.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 82.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 82.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 82.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 81.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 80.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 80.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 80.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 80.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 80.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 76.9
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 76.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 76.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 75.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 75.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 75.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 75.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 74.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 74.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 74.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 72.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 72.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 71.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 71.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 70.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 70.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 68.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 65.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 64.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 62.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 57.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 55.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 51.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 51.5
FF:10158-103A5 76 years, female 51.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 56.8
Pig sample Sample description nTPM
Midbrain
nTPM: 55.4
Samples: 4

Max nTPM: 61.4
Min nTPM: 48.4
Sample A Female 56.6
Sample B Female 48.4
Sample C Male 61.4
Sample D Male 55.2
Periaqueductal gray
nTPM: 41.9
Samples: 3

Max nTPM: 49.4
Min nTPM: 36.9
Sample B Female 39.5
Sample C Male 49.4
Sample D Male 36.9
Substantia nigra
nTPM: 50.8
Samples: 4

Max nTPM: 73.4
Min nTPM: 37.0
Sample A Female 73.4
Sample B Female 37.0
Sample C Male 54.8
Sample D Male 37.8
Superior colliculi
nTPM: 56.8
Samples: 4

Max nTPM: 69.2
Min nTPM: 38.9
Sample A Female 69.2
Sample B Female 38.9
Sample C Male 63.4
Sample D Male 55.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 100.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 100.7
Samples: 4

Max nTPM: 111.4
Min nTPM: 94.3
Sample A Male 111.4
Sample B Male 99.6
Sample C Female 94.3
Sample D Female 97.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 8.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 8.3
69174493 Antisense, RP_050329_02_D09, Mouse strain C57BL/6J (56 days, male) 8.3

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