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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
, antibody HPA042051
Photoreceptor cells
High
Limiting membrane
Not detected
Outer plexiform layer
Medium
Inner nuclear layer
Medium
Inner plexiform layer
Medium
Ganglion cells
Medium
Nerve fiber layer
Medium
RETINA - Extended tissue profilei
For selected proteins extended tissue profiling is performed in addition to standard tissue microarrays. The section below contains results from the extended profiling.
, antibody HPA044083
Pigment epithelial cells
Medium
Photoreceptor cells
Low
Limiting membrane
Not detected
Outer plexiform layer
Not detected
Inner nuclear layer
Medium
Inner plexiform layer
Not detected
Ganglion cells
Not detected
Nerve fiber layer
High
RETINA - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 551.7
Min nTPM: 105.9
Std nTPM: 83.1
Median nTPM:
394_1
75 years, female
551.7
506_1
65 years, male
466.6
4_1
88 years, female
447.3
354_1
81 years, female
436.2
189_1
76 years, male
426.0
452_1
88 years, female
424.6
264_1
73 years, female
410.8
351_1
91 years, male
395.5
406_1
79 years, male
394.3
319_1
81 years, male
382.1
308_1
70 years, female
380.4
177_1
74 years, male
372.6
163_1
78 years, male
365.1
376_1
75 years, female
360.7
349_1
83 years, male
360.1
384_1
83 years, male
350.0
115_1
83 years, male
347.4
246_1
77 years, male
345.4
375_1
74 years, female
342.9
286_1
68 years, female
339.1
350_1
84 years, female
334.9
265_1
87 years, male
333.9
379_1
60 years, male
326.3
355_1
70 years, female
311.5
173_1
67 years, male
308.4
501_1
88 years, male
307.7
137_1
83 years, male
307.3
405_1
91 years, male
307.3
389_1
86 years, female
304.8
109_1
81 years, female
304.2
353_1
82 years, female
297.4
295_1
61 years, female
296.5
356_1
87 years, female
295.9
447_1
81 years, male
295.8
396_1
62 years, male
295.1
120_1
70 years, female
294.0
517_1
88 years, male
292.3
42_1
85 years, male
288.3
386_1
76 years, male
288.3
503_1
68 years, male
284.3
172_1
72 years, female
280.1
126_1
63 years, male
279.1
518_1
75 years, female
277.8
318_1
68 years, male
273.7
119_1
70 years, female
273.0
292_1
71 years, male
271.2
313_1
79 years, female
270.9
352_1
62 years, male
270.4
377_1
82 years, female
267.0
288_1
66 years, female
262.2
314_1
67 years, male
262.2
315_1
62 years, female
260.4
243_1
75 years, male
256.3
324_1
76 years, male
253.9
320_1
89 years, female
252.8
266_1
85 years, male
252.0
413_1
59 years, female
249.9
254_1
77 years, female
249.6
468_1
89 years, male
248.1
404_1
82 years, female
244.3
35_1
74 years, female
240.9
18_1
88 years, male
240.7
17_1
71 years, male
237.4
229_1
69 years, female
236.5
316_1
62 years, male
230.3
6_1
73 years, female
229.1
99_1
64 years, male
229.1
526_1
61 years, male
227.7
425_1
59 years, female
226.9
291_1
76 years, male
223.7
9_1
66 years, female
223.1
153_1
70 years, female
223.0
142_1
61 years, female
222.8
414_1
84 years, female
221.3
217_1
76 years, male
219.0
145_1
84 years, male
215.3
89_1
63 years, male
213.1
149_1
88 years, male
212.3
317_1
60 years, male
211.5
311_1
78 years, male
209.4
348_1
84 years, male
207.5
117_1
61 years, male
207.4
81_1
67 years, male
203.5
480_1
63 years, male
201.7
162_1
79 years, female
201.3
251_1
78 years, male
200.1
335_1
73 years, female
196.7
347_1
72 years, male
184.3
499_1
55 years, female
181.4
237_1
82 years, male
180.5
32_1
67 years, male
176.9
321_1
62 years, female
173.7
293_1
68 years, female
173.5
466_1
57 years, female
170.5
218_1
71 years, female
166.8
41_1
94 years, female
156.9
491_1
89 years, female
155.7
322_1
76 years, male
154.1
2_1
77 years, female
145.9
415_1
77 years, female
139.9
307_1
66 years, female
136.2
139_1
64 years, female
126.4
43_1
64 years, female
117.8
495_1
57 years, female
106.6
490_1
67 years, female
105.9
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.