Expression of RPS2 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 516.27

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

5-year survival highⁱ N/A

5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

785.2

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	2838.4
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	2489.8
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	2225.9
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	1945.1
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	1619.4
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	1602.6
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	1477.0
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	1451.1
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	1391.4
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	1377.8
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	1336.9
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	1336.5
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	1335.4
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	1326.5
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	1316.3
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	1275.6
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	1257.9
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	1254.4
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	1250.5
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	1215.0
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	1213.9
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	1154.3
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	1139.3
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	1106.9
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	1102.4
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	1099.4
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	1081.2
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	1078.3
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	1075.1
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	1050.4
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	1048.4
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	1026.1
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	1009.2
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	997.4
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	993.9
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	988.8
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	978.2
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	941.1
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	932.1
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	924.4
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	923.6
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	921.2
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	915.7
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	912.1
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	906.7
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	902.0
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	875.3
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	849.1
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	826.4
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	822.2
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	818.5
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	816.8
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	806.8
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	804.5
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	804.2
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	801.8
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	800.6
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	800.4
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	798.9
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	794.2
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	792.6
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	779.2
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	776.5
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	763.3
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	745.6
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	743.9
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	741.7
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	741.7
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	741.5
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	735.2
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	727.4
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	726.7
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	726.4
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	719.1
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	716.0
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	715.2
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	712.9
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	712.6
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	707.7
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	702.2
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	694.8
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	694.5
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	688.2
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	683.4
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	680.7
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	666.5
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	662.3
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	661.5
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	653.9
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	652.9
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	652.9
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	650.4
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	643.7
TCGA-CL-4957-01A	79 years, female, dead, 425 days	641.3
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	640.7
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	639.6
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	638.8
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	638.1
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	637.2
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	630.4
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	630.0
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	626.8
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	623.4
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	619.1
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	616.9
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	610.2
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	608.6
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	604.4
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	595.7
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	576.7
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	566.1
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	562.6
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	555.6
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	547.2
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	541.3
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	539.6
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	535.3
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	532.7
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	530.1
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	522.7
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	518.0
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	514.5
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	513.8
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	513.1
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	492.8
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	491.2
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	490.7
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	488.8
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	488.4
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	488.1
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	485.9
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	476.2
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	472.4
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	471.2
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	458.0
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	448.7
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	436.6
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	436.1
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	432.7
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	431.1
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	430.7
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	429.8
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	428.6
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	420.0
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	418.9
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	409.5
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	408.6
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	369.6
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	358.5
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	352.5
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	349.7
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	313.4
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	299.1
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	297.5
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	294.8
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	294.8
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	292.4
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	291.4
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	253.0
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