Expression of RPL13A in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 887.01

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

5-year survival highⁱ N/A

5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

1040.6

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	3298.8
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	2349.5
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	2140.1
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	2013.3
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	1839.3
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	1772.2
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	1684.6
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	1663.2
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	1638.6
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	1587.9
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	1584.2
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	1580.5
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	1526.1
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	1509.2
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	1501.1
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	1498.2
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	1482.2
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	1463.4
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	1449.5
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	1433.9
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	1418.1
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	1377.9
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	1376.2
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	1369.8
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	1346.5
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	1346.5
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	1338.0
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	1331.3
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	1303.5
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	1302.9
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	1299.5
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	1273.0
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	1271.9
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	1265.2
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	1264.5
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	1257.5
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	1251.2
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	1238.3
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	1236.3
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	1227.9
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	1215.5
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	1213.1
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	1203.0
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	1202.2
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	1200.4
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	1200.3
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	1197.6
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	1186.1
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	1181.1
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	1180.5
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	1165.1
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	1156.8
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	1150.7
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	1144.7
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	1128.4
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	1123.5
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	1122.7
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	1122.3
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	1120.7
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	1119.7
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	1119.3
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	1108.0
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	1095.9
TCGA-CL-4957-01A	79 years, female, dead, 425 days	1089.7
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	1076.7
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	1074.1
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	1067.0
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	1050.6
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	1047.8
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	1045.9
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	1043.1
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	1038.8
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	1023.4
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	1016.7
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	1004.1
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	996.8
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	990.0
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	989.7
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	986.6
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	984.9
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	984.7
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	984.5
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	984.5
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	984.0
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	981.5
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	980.6
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	979.5
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	973.7
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	971.3
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	955.4
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	948.1
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	940.2
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	940.0
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	930.9
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	926.3
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	924.2
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	923.7
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	920.4
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	910.4
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	906.2
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	900.7
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	890.6
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	889.4
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	888.3
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	885.7
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	882.7
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	878.3
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	867.4
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	866.9
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	859.5
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	855.4
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	854.5
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	848.6
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	844.8
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	839.3
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	825.8
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	814.6
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	810.5
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	785.7
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	785.4
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	779.8
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	777.6
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	774.5
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	774.0
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	746.8
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	745.1
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	725.3
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	702.8
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	701.3
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	699.0
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	694.3
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	690.7
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	687.1
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	681.5
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	664.9
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	655.0
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	654.4
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	639.0
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	634.5
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	621.8
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	612.4
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	608.2
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	597.8
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	576.3
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	573.8
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	561.1
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	560.3
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	547.5
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	546.6
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	533.2
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	522.4
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	512.6
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	499.1
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	494.5
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	486.5
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	465.4
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	450.6
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	430.8
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	419.3
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