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  • SH3BGRL3
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:340.4 nTPM
HPA:340.4 nTPM
GTEx:159.5 nTPM
FANTOM5:287.3 Scaled Tags Per Million
Pig:347.7 nTPM
Mouse:133.5 nTPM
Allen mouse:3.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 340.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 289.1
2019 Male, age 18, unknown 314.2
2411 Female, age 72, unknown 299.4
2219 Male, age 76, both hemispheres 297.2
2666 Male, age 74, left hemisphere 295.7
2828 Female, age 72, unknown 290.8
1830 Male, age 51, unknown 285.3
1833 Male, age 53, unknown 283.9
1870 Female, age 42, unknown 281.0
1827 Male, age 72, unknown 277.3
2586 Male, age 75, left hemisphere 266.0
Dorsal raphe nucleus
nTPM: 300.2
2750 Male, age 76, both hemispheres 313.1
2047 Male, age 72, unknown 311.2
2298 Female, age 72, unknown 304.6
1828 Male, age 53, unknown 296.4
2016 Female, age 72, unknown 275.7
Inferior colliculus
nTPM: 279.9
1890 Male, age 53, unknown 286.5
2097 Female, age 72, unknown 286.1
2849 Male, age 72, unknown 274.7
1848 Female, age 42, unknown 272.5
Median raphe nucleus
nTPM: 340.4
2220 Male, age 76, midline 340.4
Pedunculopontine tegmental nucleus
nTPM: 317.5
2338 Male, age 61, both hemispheres 358.1
2334 Male, age 80, both hemispheres 313.0
1921 Female, age 85, both hemispheres 281.6
Periaquaductal grey, anterior
nTPM: 283.1
1795 Male, age 51, unknown 289.1
1947 Male, age 18, unknown 281.5
2502 Female, age 75, unknown 278.7
Periaquaductal grey, dorsal
nTPM: 279.6
2850 Male, age 76, both hemispheres 296.5
2464 Female, age 72, unknown 276.3
1831 Male, age 72, unknown 274.1
1840 Male, age 53, unknown 271.3
Periaquaductal grey, lateral
nTPM: 287.1
2272 Male, age 74, both hemispheres 312.7
2140 Male, age 76, both hemispheres 284.4
2053 Male, age 18, unknown 264.3
Pretectal area
nTPM: 295.7
2007 Male, age 72, unknown 319.3
1817 Female, age 42, unknown 318.9
1944 Female, age 72, unknown 309.4
1815 Male, age 53, unknown 307.9
2273 Male, age 74, both hemispheres 300.5
2667 Female, age 75, unknown 296.2
1816 Male, age 51, unknown 295.5
2224 Female, age 72, unknown 286.1
2407 Male, age 75, both hemispheres 281.0
2825 Male, age 18, unknown 269.7
2316 Male, age 76, right hemisphere 268.6
Red nucleus
nTPM: 289.8
2785 Male, age 18, unknown 315.8
1865 Male, age 51, unknown 297.8
2725 Female, age 75, unknown 294.9
2823 Male, age 76, right hemisphere 294.7
1904 Male, age 53, unknown 292.1
2503 Female, age 72, unknown 290.6
1954 Female, age 42, unknown 289.9
2769 Male, age 72, unknown 284.5
2227 Male, age 72, unknown 283.6
1821 Female, age 72, unknown 281.2
2588 Male, age 74, left hemisphere 278.8
2584 Male, age 75, left hemisphere 273.9
Substantia nigra
nTPM: 319.9
1916 Female, age 42, unknown 378.9
1851 Male, age 51, unknown 339.4
2699 Male, age 18, unknown 336.0
1941 Male, age 53, unknown 330.2
1889 Female, age 72, unknown 317.0
2241 Male, age 72, unknown 316.9
2409 Female, age 72, unknown 305.1
2665 Male, age 74, both hemispheres 302.8
2590 Female, age 75, unknown 289.4
2583 Male, age 75, right hemisphere 283.2
Superior colliculus
nTPM: 285.9
2668 Female, age 75, unknown 306.5
2087 Female, age 72, unknown 298.1
2587 Male, age 74, left hemisphere 296.1
1913 Female, age 42, unknown 292.7
1995 Male, age 72, unknown 287.8
1796 Male, age 53, unknown 281.8
2261 Male, age 18, unknown 281.5
1839 Male, age 51, unknown 272.4
1895 Male, age 76, right hemisphere 271.8
2664 Male, age 75, both hemispheres 270.6
Ventral tegmental area
nTPM: 311.6
1915 Female, age 42, unknown 329.2
2218 Male, age 76, both hemispheres 328.7
2410 Female, age 72, unknown 322.0
2223 Female, age 72, unknown 300.1
2021 Male, age 53, unknown 295.4
1942 Male, age 51, unknown 294.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 159.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 159.5
Samples: 139

Max nTPM: 297.5
Min nTPM: 61.2
Std nTPM: 44.9
Median nTPM: 152.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 297.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 279.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 260.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 255.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 248.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 246.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 242.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 242.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 235.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 232.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 230.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 227.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 226.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 225.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 222.8
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 222.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 222.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 222.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 214.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 212.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 212.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 211.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 211.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 207.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 205.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 204.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 200.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 199.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 199.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 195.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 194.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 194.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 194.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 191.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 190.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 190.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 188.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 185.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 185.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 184.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 183.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 182.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 182.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 179.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 178.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 175.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 174.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 171.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 166.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 166.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 164.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 162.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 160.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 159.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 159.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 158.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 157.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 157.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 156.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 155.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 155.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 154.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 154.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 154.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 154.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 154.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 153.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 153.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 152.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 152.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 149.3
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 148.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 148.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 147.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 147.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 147.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 147.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 146.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 146.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 146.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 145.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 145.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 144.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 143.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 141.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 140.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 140.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 140.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 139.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 137.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 136.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 136.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 135.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 134.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 133.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 133.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 133.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 133.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 132.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 132.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 131.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 131.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 130.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 130.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 130.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 129.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 129.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 129.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 128.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 127.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 126.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 126.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 125.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 124.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 120.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 119.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 119.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 118.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 114.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 112.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 110.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 110.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 109.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 106.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 106.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 104.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 103.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 101.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 98.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 98.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 97.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 93.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 92.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 90.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 88.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 88.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 88.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 73.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 61.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 287.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 287.3
FF:10158-103A5 76 years, female 287.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 347.7
Pig sample Sample description nTPM
Midbrain
nTPM: 318.8
Samples: 4

Max nTPM: 460.5
Min nTPM: 226.3
Sample A Female 460.5
Sample B Female 347.4
Sample C Male 241.0
Sample D Male 226.3
Periaqueductal gray
nTPM: 250.7
Samples: 3

Max nTPM: 267.3
Min nTPM: 233.3
Sample B Female 233.3
Sample C Male 251.4
Sample D Male 267.3
Substantia nigra
nTPM: 347.7
Samples: 4

Max nTPM: 470.2
Min nTPM: 241.0
Sample A Female 394.7
Sample B Female 241.0
Sample C Male 284.8
Sample D Male 470.2
Superior colliculi
nTPM: 311.5
Samples: 4

Max nTPM: 409.5
Min nTPM: 161.5
Sample A Female 409.5
Sample B Female 161.5
Sample C Male 281.2
Sample D Male 393.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 133.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 133.5
Samples: 4

Max nTPM: 144.6
Min nTPM: 124.1
Sample A Male 144.6
Sample B Male 124.1
Sample C Female 126.8
Sample D Female 138.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.0
69873708 Antisense, RP_050512_01_G10, Mouse strain C57BL/6J (56 days, male) 3.0

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