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  • ATP1B1
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:264.3 nTPM
HPA:264.3 nTPM
GTEx:351.0 nTPM
FANTOM5:705.5 Scaled Tags Per Million
Pig:586.3 nTPM
Mouse:1419.0 nTPM
Allen mouse:22.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 264.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 211.1
2019 Male, age 18, unknown 301.1
2411 Female, age 72, unknown 290.4
1827 Male, age 72, unknown 226.5
2219 Male, age 76, both hemispheres 225.4
1833 Male, age 53, unknown 201.4
1870 Female, age 42, unknown 196.2
1830 Male, age 51, unknown 193.7
2666 Male, age 74, left hemisphere 183.1
2828 Female, age 72, unknown 174.1
2586 Male, age 75, left hemisphere 119.3
Dorsal raphe nucleus
nTPM: 188.5
1828 Male, age 53, unknown 223.7
2750 Male, age 76, both hemispheres 216.2
2298 Female, age 72, unknown 200.1
2047 Male, age 72, unknown 169.8
2016 Female, age 72, unknown 132.8
Inferior colliculus
nTPM: 209.5
2097 Female, age 72, unknown 258.9
1848 Female, age 42, unknown 221.5
1890 Male, age 53, unknown 212.2
2849 Male, age 72, unknown 145.3
Median raphe nucleus
nTPM: 206.7
2220 Male, age 76, midline 206.7
Pedunculopontine tegmental nucleus
nTPM: 256.0
2334 Male, age 80, both hemispheres 277.6
1921 Female, age 85, both hemispheres 256.9
2338 Male, age 61, both hemispheres 233.6
Periaquaductal grey, anterior
nTPM: 189.4
1947 Male, age 18, unknown 221.3
1795 Male, age 51, unknown 174.7
2502 Female, age 75, unknown 172.2
Periaquaductal grey, dorsal
nTPM: 137.7
1831 Male, age 72, unknown 167.9
2464 Female, age 72, unknown 157.0
1840 Male, age 53, unknown 113.5
2850 Male, age 76, both hemispheres 112.5
Periaquaductal grey, lateral
nTPM: 159.1
2272 Male, age 74, both hemispheres 228.3
2053 Male, age 18, unknown 152.0
2140 Male, age 76, both hemispheres 96.9
Pretectal area
nTPM: 238.1
2007 Male, age 72, unknown 334.7
1817 Female, age 42, unknown 329.3
1944 Female, age 72, unknown 329.0
1816 Male, age 51, unknown 317.5
1815 Male, age 53, unknown 271.3
2273 Male, age 74, both hemispheres 213.4
2667 Female, age 75, unknown 183.3
2407 Male, age 75, both hemispheres 175.3
2224 Female, age 72, unknown 164.7
2825 Male, age 18, unknown 151.1
2316 Male, age 76, right hemisphere 149.1
Red nucleus
nTPM: 264.3
1821 Female, age 72, unknown 390.6
1954 Female, age 42, unknown 289.7
1865 Male, age 51, unknown 276.9
2785 Male, age 18, unknown 265.4
2725 Female, age 75, unknown 264.4
2823 Male, age 76, right hemisphere 254.4
2227 Male, age 72, unknown 247.9
1904 Male, age 53, unknown 245.5
2769 Male, age 72, unknown 242.5
2503 Female, age 72, unknown 239.0
2588 Male, age 74, left hemisphere 232.4
2584 Male, age 75, left hemisphere 222.7
Substantia nigra
nTPM: 261.3
1941 Male, age 53, unknown 373.6
1889 Female, age 72, unknown 340.2
1916 Female, age 42, unknown 329.4
2241 Male, age 72, unknown 277.7
1851 Male, age 51, unknown 260.4
2409 Female, age 72, unknown 255.1
2590 Female, age 75, unknown 222.0
2583 Male, age 75, right hemisphere 206.9
2699 Male, age 18, unknown 187.4
2665 Male, age 74, both hemispheres 159.7
Superior colliculus
nTPM: 212.4
2668 Female, age 75, unknown 308.4
2087 Female, age 72, unknown 290.4
1895 Male, age 76, right hemisphere 259.5
2261 Male, age 18, unknown 230.3
2587 Male, age 74, left hemisphere 227.2
1913 Female, age 42, unknown 182.4
1839 Male, age 51, unknown 182.1
1796 Male, age 53, unknown 180.7
1995 Male, age 72, unknown 159.6
2664 Male, age 75, both hemispheres 102.9
Ventral tegmental area
nTPM: 222.5
2410 Female, age 72, unknown 319.8
2218 Male, age 76, both hemispheres 271.3
1915 Female, age 42, unknown 234.7
2223 Female, age 72, unknown 190.7
1942 Male, age 51, unknown 177.9
2021 Male, age 53, unknown 140.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 351.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 351.0
Samples: 139

Max nTPM: 1928.3
Min nTPM: 39.2
Std nTPM: 279.6
Median nTPM: 285.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1928.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1500.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1188.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1042.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 1031.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 895.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 827.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 742.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 722.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 715.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 701.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 693.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 689.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 674.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 650.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 649.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 647.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 624.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 624.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 621.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 612.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 591.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 588.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 573.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 571.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 567.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 561.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 559.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 515.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 505.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 505.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 499.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 498.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 492.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 462.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 460.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 450.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 438.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 434.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 418.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 413.8
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 406.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 404.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 398.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 395.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 378.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 378.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 377.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 371.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 370.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 363.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 360.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 354.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 350.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 344.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 344.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 344.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 336.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 333.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 331.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 327.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 324.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 321.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 311.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 310.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 308.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 304.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 291.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 287.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 285.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 282.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 272.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 272.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 267.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 265.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 265.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 265.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 251.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 246.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 237.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 233.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 226.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 224.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 221.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 219.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 218.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 216.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 211.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 209.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 208.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 200.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 191.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 181.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 181.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 174.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 173.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 172.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 172.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 171.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 167.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 164.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 163.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 163.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 157.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 157.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 153.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 153.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 149.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 147.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 146.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 139.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 137.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 134.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 132.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 130.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 130.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 119.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 117.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 115.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 114.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 110.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 107.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 99.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 98.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 98.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 95.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 95.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 88.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 76.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 74.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 74.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 70.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 64.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 60.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 54.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 52.6
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 47.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 41.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 39.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 705.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 705.5
FF:10158-103A5 76 years, female 705.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 586.3
Pig sample Sample description nTPM
Midbrain
nTPM: 431.9
Samples: 4

Max nTPM: 695.4
Min nTPM: 175.4
Sample A Female 175.4
Sample B Female 253.9
Sample C Male 602.9
Sample D Male 695.4
Periaqueductal gray
nTPM: 249.6
Samples: 3

Max nTPM: 294.0
Min nTPM: 203.3
Sample B Female 251.4
Sample C Male 294.0
Sample D Male 203.3
Substantia nigra
nTPM: 319.7
Samples: 4

Max nTPM: 490.3
Min nTPM: 151.8
Sample A Female 490.3
Sample B Female 218.8
Sample C Male 417.8
Sample D Male 151.8
Superior colliculi
nTPM: 586.3
Samples: 4

Max nTPM: 771.9
Min nTPM: 319.4
Sample A Female 755.3
Sample B Female 319.4
Sample C Male 771.9
Sample D Male 498.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1419.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 1419.1
Samples: 4

Max nTPM: 1488.3
Min nTPM: 1318.3
Sample A Male 1318.3
Sample B Male 1460.4
Sample C Female 1488.3
Sample D Female 1409.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 22.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 22.7
68546368 Antisense, RP_050120_02_D04, Mouse strain C57BL/6J (56 days, male) 25.4
70919203 Antisense, RP_050712_04_D08, Mouse strain C57BL/6J (56 days, male) 20.1

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