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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:33.4 nTPM
HPA:33.4 nTPM
GTEx:76.4 nTPM
FANTOM5:41.4 Scaled Tags Per Million
Pig:30.7 nTPM
Mouse:58.2 nTPM
Allen mouse:3.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 33.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 30.4
2019 Male, age 18, unknown 35.2
2411 Female, age 72, unknown 32.3
2586 Male, age 75, left hemisphere 31.3
2666 Male, age 74, left hemisphere 31.1
1827 Male, age 72, unknown 30.7
1870 Female, age 42, unknown 29.5
2219 Male, age 76, both hemispheres 29.1
1833 Male, age 53, unknown 28.8
1830 Male, age 51, unknown 28.0
2828 Female, age 72, unknown 27.8
Dorsal raphe nucleus
nTPM: 30.3
2298 Female, age 72, unknown 33.5
1828 Male, age 53, unknown 32.0
2047 Male, age 72, unknown 29.6
2750 Male, age 76, both hemispheres 28.5
2016 Female, age 72, unknown 27.7
Inferior colliculus
nTPM: 31.2
2097 Female, age 72, unknown 34.2
1890 Male, age 53, unknown 33.0
1848 Female, age 42, unknown 29.5
2849 Male, age 72, unknown 28.1
Median raphe nucleus
nTPM: 30.0
2220 Male, age 76, midline 30.0
Pedunculopontine tegmental nucleus
nTPM: 30.3
1921 Female, age 85, both hemispheres 32.4
2334 Male, age 80, both hemispheres 30.3
2338 Male, age 61, both hemispheres 28.3
Periaquaductal grey, anterior
nTPM: 28.4
1795 Male, age 51, unknown 28.8
1947 Male, age 18, unknown 28.2
2502 Female, age 75, unknown 28.1
Periaquaductal grey, dorsal
nTPM: 29.3
1831 Male, age 72, unknown 31.1
1840 Male, age 53, unknown 29.2
2464 Female, age 72, unknown 28.5
2850 Male, age 76, both hemispheres 28.5
Periaquaductal grey, lateral
nTPM: 28.4
2053 Male, age 18, unknown 29.4
2272 Male, age 74, both hemispheres 29.1
2140 Male, age 76, both hemispheres 26.7
Pretectal area
nTPM: 33.4
1816 Male, age 51, unknown 40.4
1944 Female, age 72, unknown 37.8
1817 Female, age 42, unknown 37.7
2007 Male, age 72, unknown 37.0
1815 Male, age 53, unknown 35.0
2667 Female, age 75, unknown 31.8
2224 Female, age 72, unknown 30.5
2407 Male, age 75, both hemispheres 30.2
2316 Male, age 76, right hemisphere 29.7
2273 Male, age 74, both hemispheres 29.3
2825 Male, age 18, unknown 28.5
Red nucleus
nTPM: 30.4
1821 Female, age 72, unknown 34.0
2785 Male, age 18, unknown 33.1
2725 Female, age 75, unknown 31.0
2503 Female, age 72, unknown 30.8
1904 Male, age 53, unknown 30.4
2769 Male, age 72, unknown 30.1
1954 Female, age 42, unknown 29.9
1865 Male, age 51, unknown 29.6
2227 Male, age 72, unknown 29.6
2588 Male, age 74, left hemisphere 29.5
2823 Male, age 76, right hemisphere 29.5
2584 Male, age 75, left hemisphere 27.7
Substantia nigra
nTPM: 30.9
1889 Female, age 72, unknown 36.2
1916 Female, age 42, unknown 32.8
1851 Male, age 51, unknown 31.5
2241 Male, age 72, unknown 31.5
2583 Male, age 75, right hemisphere 30.4
2590 Female, age 75, unknown 30.3
2665 Male, age 74, both hemispheres 29.9
2409 Female, age 72, unknown 29.4
1941 Male, age 53, unknown 29.3
2699 Male, age 18, unknown 27.2
Superior colliculus
nTPM: 30.7
2087 Female, age 72, unknown 35.1
2668 Female, age 75, unknown 31.8
1895 Male, age 76, right hemisphere 31.4
2261 Male, age 18, unknown 31.1
1796 Male, age 53, unknown 30.6
1913 Female, age 42, unknown 30.2
2587 Male, age 74, left hemisphere 30.2
1995 Male, age 72, unknown 29.2
1839 Male, age 51, unknown 28.8
2664 Male, age 75, both hemispheres 28.3
Ventral tegmental area
nTPM: 30.2
2410 Female, age 72, unknown 33.3
1915 Female, age 42, unknown 31.3
2218 Male, age 76, both hemispheres 30.3
2223 Female, age 72, unknown 29.5
1942 Male, age 51, unknown 28.7
2021 Male, age 53, unknown 28.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 76.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 76.4
Samples: 139

Max nTPM: 120.3
Min nTPM: 44.9
Std nTPM: 14.6
Median nTPM: 74.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 120.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 115.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 111.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 107.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 107.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 107.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 105.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 102.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 101.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 101.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 98.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 97.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 97.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 96.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 96.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 95.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 95.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 95.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 95.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 95.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 93.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 90.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 90.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 88.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 87.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 87.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 87.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 87.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 87.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 87.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 87.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 86.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 86.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 86.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 85.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 85.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 85.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 85.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 85.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 84.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 84.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 84.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 84.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 83.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 83.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 83.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 81.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 81.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 81.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 79.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 79.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 78.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 78.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 77.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 77.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 76.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 76.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 76.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 75.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 75.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 75.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 75.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 75.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 75.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 75.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 75.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 74.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 74.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 74.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 74.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 74.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 74.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 73.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 73.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 73.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 73.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 72.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 72.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 72.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 72.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 72.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 72.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 72.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 71.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 71.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 70.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 70.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 70.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 70.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 69.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 69.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 69.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 69.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 68.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 68.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 68.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 68.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 68.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 67.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 67.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 67.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 66.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 66.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 66.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 66.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 66.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 65.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 65.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 65.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 65.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 64.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 64.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 63.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 62.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 62.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 62.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 62.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 62.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 61.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 61.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 61.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 60.3
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 60.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 60.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 60.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 59.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 59.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 58.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 57.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 57.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 57.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 56.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 56.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 55.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 53.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 50.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 49.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 45.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 44.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 41.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 41.4
FF:10158-103A5 76 years, female 41.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 30.7
Pig sample Sample description nTPM
Midbrain
nTPM: 29.1
Samples: 4

Max nTPM: 31.1
Min nTPM: 26.9
Sample A Female 27.8
Sample B Female 26.9
Sample C Male 31.1
Sample D Male 30.6
Periaqueductal gray
nTPM: 25.2
Samples: 3

Max nTPM: 26.1
Min nTPM: 24.0
Sample B Female 26.1
Sample C Male 24.0
Sample D Male 25.4
Substantia nigra
nTPM: 26.1
Samples: 4

Max nTPM: 28.2
Min nTPM: 24.3
Sample A Female 26.0
Sample B Female 24.3
Sample C Male 25.8
Sample D Male 28.2
Superior colliculi
nTPM: 30.7
Samples: 4

Max nTPM: 33.2
Min nTPM: 26.2
Sample A Female 32.2
Sample B Female 26.2
Sample C Male 33.2
Sample D Male 31.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 58.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 58.2
Samples: 4

Max nTPM: 65.1
Min nTPM: 55.3
Sample A Male 57.0
Sample B Male 55.3
Sample C Female 55.4
Sample D Female 65.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.3
79393535 Antisense, RP_071018_02_B02, Mouse strain C57BL/6J (56 days, male) 3.3

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