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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:468.0 nTPM
HPA:468.0 nTPM
FANTOM5:227.4 Scaled Tags Per Million
Pig:223.5 nTPM
Allen mouse:6.4 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 468.0
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 278.8
2301 Female, age 85, both hemispheres 491.9
2188 Female, age 91, both hemispheres 431.5
2090 Male, age 80, both hemispheres 124.3
1984 Male, age 76, both hemispheres 67.6
Dorsal cochlear nucleus
nTPM: 165.4
2187 Female, age 91, both hemispheres 255.0
2378 Male, age 80, both hemispheres 235.3
2802 Male, age 74, right hemisphere 123.2
2058 Male, age 76, both hemispheres 109.8
2370 Male, age 61, both hemispheres 103.6
Dorsal tegmental nucleus
nTPM: 263.6
2326 Male, age 74, both hemispheres 339.8
2083 Male, age 80, both hemispheres 303.0
2358 Male, age 61, both hemispheres 206.5
1936 Male, age 76, left hemisphere 205.0
Dorsolateral tegmental area
nTPM: 167.1
2751 Female, age 85, both hemispheres 289.4
2337 Male, age 61, both hemispheres 288.7
2141 Male, age 76, both hemispheres 109.5
2654 Male, age 80, both hemispheres 97.4
2360 Male, age 74, both hemispheres 50.5
Kolliker-Fuse nucleus
nTPM: 230.7
2793 Female, age 91, left hemisphere 442.2
2163 Male, age 80, both hemispheres 205.0
2315 Male, age 76, right hemisphere 44.9
Lateral lemniscal nuclei
nTPM: 212.9
2320 Female, age 91, left hemisphere 369.9
2169 Male, age 76, both hemispheres 323.1
2453 Male, age 74, right hemisphere 311.3
2746 Female, age 85, left hemisphere 60.5
2036 Male, age 80, both hemispheres 0.0
Lateral parabrachial nucleus
nTPM: 106.6
2792 Male, age 76, both hemispheres 284.0
2139 Female, age 85, right hemisphere 74.9
2790 Male, age 61, both hemispheres 36.8
2013 Male, age 80, both hemispheres 30.8
Lateral vestibular nucleus
nTPM: 468.0
2311 Male, age 80, both hemispheres 515.5
2184 Male, age 76, both hemispheres 420.5
Locus coeruleus
nTPM: 128.2
2317 Female, age 72, unknown 212.8
2720 Male, age 74, both hemispheres 199.5
2162 Male, age 80, both hemispheres 196.6
2788 Male, age 74, unknown 119.6
2014 Male, age 55, unknown 86.1
1980 Male, age 76, both hemispheres 77.1
2123 Female, age 91, both hemispheres 5.8
Medial olivary nucleus
nTPM: 107.8
2851 Male, age 80, both hemispheres 213.2
1962 Male, age 76, both hemispheres 91.5
1943 Male, age 61, both hemispheres 82.4
2138 Female, age 91, both hemispheres 43.9
Medial parabrachial nucleus
nTPM: 206.0
2170 Female, age 91, both hemispheres 339.8
2156 Male, age 61, both hemispheres 305.3
2854 Male, age 80, both hemispheres 230.6
2786 Male, age 76, both hemispheres 154.7
2463 Female, age 85, right hemisphere 0.0
Medial periolivary nuclei
nTPM: 103.4
2458 Female, age 91, both hemispheres 281.0
2171 Female, age 85, both hemispheres 146.2
2063 Male, age 76, both hemispheres 66.2
2081 Male, age 80, both hemispheres 23.7
2791 Male, age 74, right hemisphere 0.0
Motor facial nucleus
nTPM: 137.3
2697 Female, age 85, both hemispheres 345.8
2327 Male, age 80, both hemispheres 188.7
2795 Female, age 91, both hemispheres 171.7
2365 Male, age 74, right hemisphere 73.4
2062 Male, age 76, both hemispheres 44.1
2126 Male, age 61, both hemispheres 0.0
Motor trigeminal nucleus
nTPM: 215.4
2309 Male, age 76, both hemispheres 370.2
2321 Female, age 91, both hemispheres 359.4
2335 Male, age 61, both hemispheres 154.1
2079 Male, age 80, both hemispheres 112.0
2560 Male, age 74, both hemispheres 81.6
Nuclei of the trapezoid body
nTPM: 155.0
1983 Male, age 76, both hemispheres 248.6
2368 Female, age 91, both hemispheres 238.6
2166 Male, age 80, both hemispheres 156.1
2159 Male, age 61, both hemispheres 81.0
2735 Female, age 85, both hemispheres 50.7
Paramedian reticular nucleus
nTPM: 131.5
2313 Male, age 61, both hemispheres 249.1
2052 Male, age 76, both hemispheres 130.5
2050 Female, age 85, both hemispheres 100.2
2057 Male, age 80, both hemispheres 46.1
Pontine nuclei
nTPM: 109.8
2319 Female, age 91, both hemispheres 407.6
2787 Female, age 85, both hemispheres 147.6
2454 Male, age 74, left hemisphere 134.5
1863 Male, age 55, unknown 117.7
1968 Male, age 76, left hemisphere 59.8
2115 Male, age 80, left hemisphere 10.4
2727 Male, age 61, right hemisphere 0.9
2109 Female, age 72, unknown 0.0
Pontine raphe nucleus
nTPM: 240.9
2853 Male, age 76, midline 314.9
2122 Female, age 85, midline 166.9
Posteroventral cochlear nucleus
nTPM: 219.8
2341 Male, age 80, both hemispheres 431.2
2371 Male, age 61, both hemispheres 253.2
2135 Female, age 91, both hemispheres 223.6
2752 Female, age 85, both hemispheres 191.2
2070 Male, age 76, both hemispheres 0.0
Principal sensory trigeminal nucleus
nTPM: 189.8
2367 Female, age 91, left hemisphere 400.8
2324 Male, age 76, both hemispheres 332.6
2008 Male, age 80, left hemisphere 25.9
2158 Male, age 61, both hemispheres 0.0
Reticular pontine nucleus, caudal
nTPM: 212.4
2457 Female, age 91, both hemispheres 401.3
2559 Male, age 74, both hemispheres 185.9
2092 Male, age 76, both hemispheres 149.9
2332 Male, age 80, right hemisphere 112.4
Reticular pontine nucleus, oral
nTPM: 234.3
2366 Female, age 91, both hemispheres 503.1
2167 Male, age 76, both hemispheres 297.4
1939 Male, age 80, both hemispheres 201.3
2012 Female, age 85, both hemispheres 126.0
2361 Male, age 74, both hemispheres 43.9
Reticulotegmental nucleus
nTPM: 423.5
2452 Male, age 74, both hemispheres 506.9
2325 Male, age 76, both hemispheres 413.3
2322 Female, age 91, both hemispheres 389.9
2333 Male, age 80, both hemispheres 384.0
Spinal trigeminal nucleus, oral
nTPM: 169.3
2164 Male, age 80, both hemispheres 238.1
1978 Male, age 76, both hemispheres 138.0
2737 Female, age 85, both hemispheres 131.9
Subcoeruleus area
nTPM: 251.6
2451 Male, age 74, both hemispheres 557.2
2323 Female, age 91, left hemisphere 317.5
2369 Female, age 85, left hemisphere 167.2
2089 Male, age 76, left hemisphere 111.1
1958 Male, age 80, both hemispheres 105.0
Superior olive
nTPM: 155.1
2329 Male, age 80, right hemisphere 250.6
2020 Male, age 76, both hemispheres 248.8
2561 Female, age 91, both hemispheres 161.4
1875 Female, age 85, both hemispheres 106.3
2364 Male, age 74, right hemisphere 8.2
Superior vestibular nucleus
nTPM: 122.0
2015 Male, age 80, both hemispheres 179.3
2383 Male, age 74, both hemispheres 161.5
2061 Male, age 76, both hemispheres 25.2
Ventral periolivary nuclei
nTPM: 94.8
2165 Male, age 80, both hemispheres 239.5
2794 Female, age 91, left hemisphere 136.8
2023 Male, age 76, both hemispheres 3.0
2130 Female, age 85, both hemispheres 0.0
Ventrolateral tegmental area, A5 NE cell group
nTPM: 202.7
2840 Female, age 85, both hemispheres 236.2
2456 Female, age 91, both hemispheres 231.2
2359 Male, age 61, both hemispheres 211.9
2161 Male, age 80, both hemispheres 189.8
1959 Male, age 76, both hemispheres 177.2
2449 Male, age 74, both hemispheres 169.8

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 227.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 138.8
FF:10182-103D2 60 years, female 179.9
FF:10165-103B3 76 years, female 97.7
Pons
Scaled Tags Per Million: 227.4
FF:10033-101E6 18-54 years, mixed 227.4

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 223.5
Pig sample Sample description nTPM
Pons
nTPM: 223.5
Samples: 4

Max nTPM: 354.7
Min nTPM: 176.6
Sample A Female 354.7
Sample B Female 176.6
Sample C Male 185.7
Sample D Male 177.1

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 6.4
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 6.4
71358557 Antisense, RP_050725_03_E06, Mouse strain C57BL/6J (56 days, male) 7.3
68798938 Antisense, RP_050217_01_F04, Mouse strain C57BL/6J (56 days, male) 5.6

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.