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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 123.6
Min nTPM: 47.7
Std nTPM: 14.8
Median nTPM:
490_1
67 years, female
123.6
491_1
89 years, female
111.8
414_1
84 years, female
109.1
413_1
59 years, female
105.5
308_1
70 years, female
104.8
495_1
57 years, female
100.5
162_1
79 years, female
100.4
89_1
63 years, male
94.0
149_1
88 years, male
92.8
415_1
77 years, female
92.8
2_1
77 years, female
90.7
501_1
88 years, male
89.2
41_1
94 years, female
88.7
42_1
85 years, male
88.3
315_1
62 years, female
87.3
119_1
70 years, female
86.4
99_1
64 years, male
85.9
117_1
61 years, male
84.7
120_1
70 years, female
84.5
307_1
66 years, female
83.6
109_1
81 years, female
81.8
384_1
83 years, male
81.2
347_1
72 years, male
80.9
466_1
57 years, female
80.9
32_1
67 years, male
80.1
139_1
64 years, female
79.3
81_1
67 years, male
77.7
254_1
77 years, female
77.2
265_1
87 years, male
76.8
6_1
73 years, female
76.6
43_1
64 years, female
76.3
126_1
63 years, male
76.3
35_1
74 years, female
75.8
447_1
81 years, male
75.4
246_1
77 years, male
74.9
115_1
83 years, male
74.3
404_1
82 years, female
73.9
499_1
55 years, female
73.9
313_1
79 years, female
73.7
173_1
67 years, male
73.5
324_1
76 years, male
73.2
266_1
85 years, male
73.1
189_1
76 years, male
73.0
17_1
71 years, male
72.9
9_1
66 years, female
72.6
142_1
61 years, female
72.5
145_1
84 years, male
72.4
379_1
60 years, male
71.9
153_1
70 years, female
70.7
317_1
60 years, male
70.6
348_1
84 years, male
70.4
18_1
88 years, male
69.7
526_1
61 years, male
69.7
314_1
67 years, male
68.4
468_1
89 years, male
68.4
322_1
76 years, male
67.7
229_1
69 years, female
67.4
311_1
78 years, male
67.4
217_1
76 years, male
67.3
389_1
86 years, female
66.9
396_1
62 years, male
66.7
243_1
75 years, male
66.1
321_1
62 years, female
66.0
386_1
76 years, male
65.6
355_1
70 years, female
64.7
518_1
75 years, female
64.6
375_1
74 years, female
64.0
517_1
88 years, male
63.8
237_1
82 years, male
63.6
503_1
68 years, male
63.3
288_1
66 years, female
62.2
335_1
73 years, female
62.0
452_1
88 years, female
62.0
137_1
83 years, male
61.6
295_1
61 years, female
61.3
377_1
82 years, female
61.3
405_1
91 years, male
61.3
172_1
72 years, female
60.9
177_1
74 years, male
60.8
376_1
75 years, female
59.8
4_1
88 years, female
59.7
319_1
81 years, male
59.5
251_1
78 years, male
59.4
350_1
84 years, female
59.0
349_1
83 years, male
58.5
318_1
68 years, male
58.4
506_1
65 years, male
58.4
286_1
68 years, female
57.7
406_1
79 years, male
57.4
425_1
59 years, female
56.7
394_1
75 years, female
56.3
480_1
63 years, male
55.4
291_1
76 years, male
55.2
351_1
91 years, male
54.9
218_1
71 years, female
53.5
293_1
68 years, female
53.4
353_1
82 years, female
53.1
264_1
73 years, female
53.0
320_1
89 years, female
53.0
316_1
62 years, male
52.9
292_1
71 years, male
51.6
356_1
87 years, female
50.9
352_1
62 years, male
49.6
354_1
81 years, female
49.3
163_1
78 years, male
47.7
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
