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EIF4A2
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  • EIF4A2
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:254.5 nTPM
HPA:254.5 nTPM
GTEx:202.1 nTPM
FANTOM5:399.8 Scaled Tags Per Million
Pig:522.5 nTPM
Mouse:847.3 nTPM
Allen mouse:22.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 254.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 231.8
1827 Male, age 72, unknown 247.6
2019 Male, age 18, unknown 242.5
2411 Female, age 72, unknown 242.3
1870 Female, age 42, unknown 240.9
2219 Male, age 76, both hemispheres 236.1
2666 Male, age 74, left hemisphere 229.0
1833 Male, age 53, unknown 224.0
2586 Male, age 75, left hemisphere 221.8
1830 Male, age 51, unknown 221.2
2828 Female, age 72, unknown 212.7
Dorsal raphe nucleus
nTPM: 234.7
2298 Female, age 72, unknown 263.6
2047 Male, age 72, unknown 234.6
1828 Male, age 53, unknown 229.5
2750 Male, age 76, both hemispheres 227.2
2016 Female, age 72, unknown 218.4
Inferior colliculus
nTPM: 254.1
2097 Female, age 72, unknown 274.4
1848 Female, age 42, unknown 248.5
1890 Male, age 53, unknown 247.7
2849 Male, age 72, unknown 246.0
Median raphe nucleus
nTPM: 254.5
2220 Male, age 76, midline 254.5
Pedunculopontine tegmental nucleus
nTPM: 250.2
1921 Female, age 85, both hemispheres 256.4
2334 Male, age 80, both hemispheres 251.3
2338 Male, age 61, both hemispheres 243.0
Periaquaductal grey, anterior
nTPM: 248.4
1947 Male, age 18, unknown 254.3
2502 Female, age 75, unknown 251.4
1795 Male, age 51, unknown 239.5
Periaquaductal grey, dorsal
nTPM: 236.5
1840 Male, age 53, unknown 248.3
2464 Female, age 72, unknown 234.2
1831 Male, age 72, unknown 232.8
2850 Male, age 76, both hemispheres 230.9
Periaquaductal grey, lateral
nTPM: 229.6
2053 Male, age 18, unknown 234.4
2272 Male, age 74, both hemispheres 231.4
2140 Male, age 76, both hemispheres 223.2
Pretectal area
nTPM: 249.1
1816 Male, age 51, unknown 271.2
2007 Male, age 72, unknown 266.1
1817 Female, age 42, unknown 265.0
1944 Female, age 72, unknown 260.5
2224 Female, age 72, unknown 260.1
1815 Male, age 53, unknown 245.7
2667 Female, age 75, unknown 244.9
2825 Male, age 18, unknown 238.7
2273 Male, age 74, both hemispheres 233.2
2407 Male, age 75, both hemispheres 227.4
2316 Male, age 76, right hemisphere 226.8
Red nucleus
nTPM: 231.9
1821 Female, age 72, unknown 264.4
2725 Female, age 75, unknown 242.8
2785 Male, age 18, unknown 236.9
1865 Male, age 51, unknown 233.5
1954 Female, age 42, unknown 233.0
2227 Male, age 72, unknown 228.0
2503 Female, age 72, unknown 227.3
2769 Male, age 72, unknown 226.9
1904 Male, age 53, unknown 226.1
2584 Male, age 75, left hemisphere 224.2
2588 Male, age 74, left hemisphere 220.7
2823 Male, age 76, right hemisphere 218.6
Substantia nigra
nTPM: 236.5
1889 Female, age 72, unknown 260.8
1941 Male, age 53, unknown 247.9
2241 Male, age 72, unknown 247.7
2409 Female, age 72, unknown 239.3
2665 Male, age 74, both hemispheres 237.6
1916 Female, age 42, unknown 233.6
1851 Male, age 51, unknown 232.7
2590 Female, age 75, unknown 229.9
2583 Male, age 75, right hemisphere 224.8
2699 Male, age 18, unknown 210.4
Superior colliculus
nTPM: 236.0
1895 Male, age 76, right hemisphere 254.5
2587 Male, age 74, left hemisphere 246.8
2261 Male, age 18, unknown 246.3
1796 Male, age 53, unknown 246.1
1839 Male, age 51, unknown 239.7
2087 Female, age 72, unknown 237.4
2668 Female, age 75, unknown 229.1
2664 Male, age 75, both hemispheres 223.3
1913 Female, age 42, unknown 223.2
1995 Male, age 72, unknown 213.2
Ventral tegmental area
nTPM: 235.8
2223 Female, age 72, unknown 243.2
2410 Female, age 72, unknown 240.3
1915 Female, age 42, unknown 239.5
2218 Male, age 76, both hemispheres 233.3
1942 Male, age 51, unknown 232.0
2021 Male, age 53, unknown 226.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 202.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 202.1
Samples: 139

Max nTPM: 694.6
Min nTPM: 90.8
Std nTPM: 86.1
Median nTPM: 184.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 694.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 556.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 522.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 416.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 401.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 363.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 360.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 328.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 324.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 316.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 316.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 309.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 308.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 305.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 297.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 289.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 289.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 284.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 283.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 279.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 279.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 277.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 259.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 257.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 256.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 251.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 242.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 242.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 237.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 229.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 226.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 226.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 224.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 223.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 222.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 221.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 220.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 220.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 218.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 216.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 215.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 214.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 211.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 211.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 211.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 210.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 204.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 204.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 202.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 200.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 200.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 199.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 198.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 198.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 197.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 196.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 196.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 195.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 192.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 189.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 188.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 188.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 188.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 188.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 186.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 186.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 186.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 185.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 185.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 184.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 183.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 183.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 182.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 181.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 180.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 180.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 179.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 179.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 179.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 179.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 178.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 177.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 177.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 176.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 176.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 175.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 175.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 174.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 173.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 169.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 169.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 167.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 167.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 163.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 162.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 161.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 157.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 155.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 155.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 154.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 153.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 153.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 150.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 145.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 144.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 144.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 144.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 143.5
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 143.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 142.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 142.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 141.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 140.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 140.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 138.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 137.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 137.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 136.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 136.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 135.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 135.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 133.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 128.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 127.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 126.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 123.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 123.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 116.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 116.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 111.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 108.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 107.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 103.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 102.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 101.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 98.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 95.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 94.3
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 90.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 399.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 399.8
FF:10158-103A5 76 years, female 399.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 522.5
Pig sample Sample description nTPM
Midbrain
nTPM: 476.6
Samples: 4

Max nTPM: 545.1
Min nTPM: 392.9
Sample A Female 448.9
Sample B Female 392.9
Sample C Male 545.1
Sample D Male 519.3
Periaqueductal gray
nTPM: 350.5
Samples: 3

Max nTPM: 393.6
Min nTPM: 327.2
Sample B Female 330.7
Sample C Male 393.6
Sample D Male 327.2
Substantia nigra
nTPM: 396.5
Samples: 4

Max nTPM: 585.5
Min nTPM: 245.1
Sample A Female 585.5
Sample B Female 365.6
Sample C Male 389.9
Sample D Male 245.1
Superior colliculi
nTPM: 522.5
Samples: 4

Max nTPM: 613.4
Min nTPM: 439.2
Sample A Female 613.4
Sample B Female 439.2
Sample C Male 565.9
Sample D Male 471.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 847.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 847.4
Samples: 4

Max nTPM: 859.3
Min nTPM: 838.1
Sample A Male 843.9
Sample B Male 859.3
Sample C Female 838.1
Sample D Female 848.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 22.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 22.3
71381013 Antisense, RP_050428_02_F12, Mouse strain C57BL/6J (56 days, male) 22.3

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