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A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Protein expressioni
On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max nTPM: 87.7
Min nTPM: 31.2
Std nTPM: 7.9
Median nTPM:
218_1
71 years, female
87.7
319_1
81 years, male
68.5
237_1
82 years, male
66.4
377_1
82 years, female
65.8
375_1
74 years, female
64.2
320_1
89 years, female
63.1
243_1
75 years, male
62.5
35_1
74 years, female
62.0
286_1
68 years, female
61.4
137_1
83 years, male
61.3
384_1
83 years, male
61.2
163_1
78 years, male
60.1
354_1
81 years, female
59.8
386_1
76 years, male
59.8
293_1
68 years, female
59.6
99_1
64 years, male
59.1
246_1
77 years, male
58.7
347_1
72 years, male
58.5
405_1
91 years, male
58.3
353_1
82 years, female
58.2
356_1
87 years, female
58.2
335_1
73 years, female
58.0
506_1
65 years, male
57.9
425_1
59 years, female
57.6
321_1
62 years, female
57.4
350_1
84 years, female
57.3
394_1
75 years, female
57.1
172_1
72 years, female
57.0
406_1
79 years, male
57.0
447_1
81 years, male
56.9
452_1
88 years, female
56.8
379_1
60 years, male
56.7
322_1
76 years, male
56.6
173_1
67 years, male
56.4
355_1
70 years, female
56.2
41_1
94 years, female
56.1
17_1
71 years, male
56.0
189_1
76 years, male
55.8
376_1
75 years, female
55.7
229_1
69 years, female
55.3
42_1
85 years, male
54.9
295_1
61 years, female
54.9
4_1
88 years, female
54.8
292_1
71 years, male
54.3
349_1
83 years, male
54.2
264_1
73 years, female
54.1
318_1
68 years, male
53.5
480_1
63 years, male
53.1
6_1
73 years, female
53.0
317_1
60 years, male
53.0
352_1
62 years, male
52.6
251_1
78 years, male
52.4
316_1
62 years, male
52.3
351_1
91 years, male
52.1
313_1
79 years, female
52.0
145_1
84 years, male
51.5
153_1
70 years, female
51.1
503_1
68 years, male
51.1
177_1
74 years, male
50.9
404_1
82 years, female
50.8
396_1
62 years, male
50.7
415_1
77 years, female
50.4
115_1
83 years, male
50.1
518_1
75 years, female
49.7
266_1
85 years, male
49.5
315_1
62 years, female
49.2
324_1
76 years, male
49.2
142_1
61 years, female
49.1
526_1
61 years, male
48.6
389_1
86 years, female
48.4
265_1
87 years, male
48.1
254_1
77 years, female
47.9
517_1
88 years, male
47.8
413_1
59 years, female
47.5
466_1
57 years, female
47.1
288_1
66 years, female
47.0
311_1
78 years, male
46.7
18_1
88 years, male
46.5
217_1
76 years, male
45.8
495_1
57 years, female
45.7
9_1
66 years, female
45.3
307_1
66 years, female
45.3
490_1
67 years, female
45.2
117_1
61 years, male
45.1
468_1
89 years, male
45.1
81_1
67 years, male
44.1
126_1
63 years, male
44.1
120_1
70 years, female
44.0
348_1
84 years, male
43.9
501_1
88 years, male
43.9
291_1
76 years, male
43.6
109_1
81 years, female
43.2
119_1
70 years, female
43.2
499_1
55 years, female
42.8
43_1
64 years, female
42.7
314_1
67 years, male
42.6
2_1
77 years, female
42.5
162_1
79 years, female
42.5
139_1
64 years, female
42.2
308_1
70 years, female
42.0
32_1
67 years, male
41.2
414_1
84 years, female
40.9
491_1
89 years, female
35.9
89_1
63 years, male
35.5
149_1
88 years, male
31.2
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RETINA - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
The Human Protein Atlas project is funded
