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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:327.9 nTPM
HPA:327.9 nTPM
GTEx:830.4 nTPM
FANTOM5:864.0 Scaled Tags Per Million
Pig:167.5 nTPM
Mouse:19.1 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 327.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 298.8
1830 Male, age 51, unknown 320.4
1833 Male, age 53, unknown 318.6
2411 Female, age 72, unknown 305.9
1870 Female, age 42, unknown 305.3
2828 Female, age 72, unknown 301.1
2219 Male, age 76, both hemispheres 293.4
2586 Male, age 75, left hemisphere 290.8
2666 Male, age 74, left hemisphere 290.5
2019 Male, age 18, unknown 289.5
1827 Male, age 72, unknown 272.7
Dorsal raphe nucleus
nTPM: 272.6
2750 Male, age 76, both hemispheres 341.3
2016 Female, age 72, unknown 270.4
1828 Male, age 53, unknown 266.1
2047 Male, age 72, unknown 244.0
2298 Female, age 72, unknown 241.1
Inferior colliculus
nTPM: 266.0
2849 Male, age 72, unknown 291.2
1848 Female, age 42, unknown 273.6
1890 Male, age 53, unknown 256.7
2097 Female, age 72, unknown 242.6
Median raphe nucleus
nTPM: 285.6
2220 Male, age 76, midline 285.6
Pedunculopontine tegmental nucleus
nTPM: 274.7
2334 Male, age 80, both hemispheres 302.9
2338 Male, age 61, both hemispheres 261.8
1921 Female, age 85, both hemispheres 259.3
Periaquaductal grey, anterior
nTPM: 257.9
2502 Female, age 75, unknown 261.6
1947 Male, age 18, unknown 256.2
1795 Male, age 51, unknown 256.0
Periaquaductal grey, dorsal
nTPM: 255.7
2464 Female, age 72, unknown 271.4
1831 Male, age 72, unknown 259.0
1840 Male, age 53, unknown 246.8
2850 Male, age 76, both hemispheres 245.5
Periaquaductal grey, lateral
nTPM: 259.4
2053 Male, age 18, unknown 273.3
2272 Male, age 74, both hemispheres 265.5
2140 Male, age 76, both hemispheres 239.4
Pretectal area
nTPM: 257.4
2316 Male, age 76, right hemisphere 281.9
1815 Male, age 53, unknown 272.2
2825 Male, age 18, unknown 265.8
2407 Male, age 75, both hemispheres 261.7
2224 Female, age 72, unknown 259.9
1817 Female, age 42, unknown 257.9
2273 Male, age 74, both hemispheres 253.1
2667 Female, age 75, unknown 248.7
2007 Male, age 72, unknown 247.9
1944 Female, age 72, unknown 243.4
1816 Male, age 51, unknown 238.8
Red nucleus
nTPM: 327.9
2769 Male, age 72, unknown 365.6
2227 Male, age 72, unknown 360.9
2503 Female, age 72, unknown 356.5
2588 Male, age 74, left hemisphere 348.2
1865 Male, age 51, unknown 339.5
2823 Male, age 76, right hemisphere 338.0
1904 Male, age 53, unknown 337.7
2785 Male, age 18, unknown 310.2
1954 Female, age 42, unknown 310.1
1821 Female, age 72, unknown 297.8
2584 Male, age 75, left hemisphere 289.9
2725 Female, age 75, unknown 279.8
Substantia nigra
nTPM: 267.4
2590 Female, age 75, unknown 294.8
2665 Male, age 74, both hemispheres 287.4
2583 Male, age 75, right hemisphere 285.6
2699 Male, age 18, unknown 279.5
1851 Male, age 51, unknown 276.3
1889 Female, age 72, unknown 262.9
1941 Male, age 53, unknown 256.4
1916 Female, age 42, unknown 249.1
2241 Male, age 72, unknown 241.8
2409 Female, age 72, unknown 240.7
Superior colliculus
nTPM: 276.6
1913 Female, age 42, unknown 304.2
1995 Male, age 72, unknown 296.4
2587 Male, age 74, left hemisphere 289.2
2668 Female, age 75, unknown 288.4
1839 Male, age 51, unknown 281.8
1895 Male, age 76, right hemisphere 268.4
1796 Male, age 53, unknown 265.6
2664 Male, age 75, both hemispheres 259.0
2087 Female, age 72, unknown 258.9
2261 Male, age 18, unknown 253.8
Ventral tegmental area
nTPM: 293.4
2223 Female, age 72, unknown 350.4
2218 Male, age 76, both hemispheres 293.4
2410 Female, age 72, unknown 293.2
2021 Male, age 53, unknown 289.7
1942 Male, age 51, unknown 273.6
1915 Female, age 42, unknown 260.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 830.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 830.4
Samples: 139

Max nTPM: 2645.5
Min nTPM: 102.6
Std nTPM: 486.3
Median nTPM: 731.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 2645.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 2412.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 2322.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 2057.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 2040.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 2008.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1951.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1895.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 1890.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1822.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 1748.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1739.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 1613.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1485.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1423.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1409.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1405.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1390.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1370.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 1345.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1317.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1272.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1247.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1182.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1152.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1127.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1120.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1113.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1113.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1070.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1042.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1032.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1031.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1009.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1006.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 993.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 989.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 980.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 972.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 965.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 937.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 927.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 906.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 905.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 890.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 880.6
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 873.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 868.1
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 864.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 838.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 837.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 835.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 812.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 810.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 809.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 789.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 786.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 773.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 770.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 765.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 760.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 759.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 758.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 756.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 753.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 745.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 745.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 740.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 734.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 731.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 711.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 709.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 704.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 703.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 698.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 681.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 671.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 661.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 654.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 641.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 634.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 624.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 620.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 614.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 613.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 612.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 607.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 599.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 591.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 591.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 577.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 577.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 575.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 569.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 568.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 567.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 546.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 543.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 532.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 527.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 513.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 508.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 503.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 499.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 491.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 479.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 469.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 467.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 451.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 448.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 445.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 442.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 441.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 437.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 437.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 419.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 414.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 408.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 406.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 403.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 396.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 392.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 388.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 380.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 373.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 371.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 360.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 359.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 317.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 314.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 289.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 287.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 281.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 263.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 242.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 218.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 205.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 179.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 102.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 864.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 864.0
FF:10158-103A5 76 years, female 864.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 167.5
Pig sample Sample description nTPM
Midbrain
nTPM: 167.5
Samples: 4

Max nTPM: 414.8
Min nTPM: 58.2
Sample A Female 414.8
Sample B Female 125.5
Sample C Male 71.4
Sample D Male 58.2
Periaqueductal gray
nTPM: 79.6
Samples: 3

Max nTPM: 83.6
Min nTPM: 72.1
Sample B Female 83.6
Sample C Male 72.1
Sample D Male 83.2
Substantia nigra
nTPM: 130.4
Samples: 4

Max nTPM: 200.8
Min nTPM: 83.8
Sample A Female 123.9
Sample B Female 83.8
Sample C Male 113.1
Sample D Male 200.8
Superior colliculi
nTPM: 99.1
Samples: 4

Max nTPM: 131.8
Min nTPM: 57.9
Sample A Female 90.3
Sample B Female 57.9
Sample C Male 116.4
Sample D Male 131.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 19.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 19.1
Samples: 4

Max nTPM: 25.5
Min nTPM: 14.2
Sample A Male 25.5
Sample B Male 18.0
Sample C Female 14.2
Sample D Female 18.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
73712816 Antisense, RP_051206_02_D12, Mouse strain C57BL/6J (56 days, male) 0.1

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