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RPL8
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:195.2 nTPM
HPA:195.2 nTPM
GTEx:579.7 nTPM
FANTOM5:177.7 Scaled Tags Per Million
Pig:324.4 nTPM
Mouse:473.1 nTPM
Allen mouse:12.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 195.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 175.7
2586 Male, age 75, left hemisphere 189.3
1870 Female, age 42, unknown 182.3
2828 Female, age 72, unknown 180.7
2019 Male, age 18, unknown 178.8
2666 Male, age 74, left hemisphere 176.2
1827 Male, age 72, unknown 175.3
2411 Female, age 72, unknown 174.1
2219 Male, age 76, both hemispheres 169.5
1830 Male, age 51, unknown 165.9
1833 Male, age 53, unknown 165.1
Dorsal raphe nucleus
nTPM: 180.8
2298 Female, age 72, unknown 197.0
2750 Male, age 76, both hemispheres 183.7
1828 Male, age 53, unknown 180.7
2016 Female, age 72, unknown 175.6
2047 Male, age 72, unknown 167.1
Inferior colliculus
nTPM: 175.9
2097 Female, age 72, unknown 185.2
1890 Male, age 53, unknown 183.8
1848 Female, age 42, unknown 171.5
2849 Male, age 72, unknown 162.9
Median raphe nucleus
nTPM: 180.5
2220 Male, age 76, midline 180.5
Pedunculopontine tegmental nucleus
nTPM: 191.2
2338 Male, age 61, both hemispheres 202.4
2334 Male, age 80, both hemispheres 200.2
1921 Female, age 85, both hemispheres 171.0
Periaquaductal grey, anterior
nTPM: 195.2
2502 Female, age 75, unknown 214.4
1795 Male, age 51, unknown 189.1
1947 Male, age 18, unknown 181.9
Periaquaductal grey, dorsal
nTPM: 171.5
1831 Male, age 72, unknown 179.3
1840 Male, age 53, unknown 176.6
2464 Female, age 72, unknown 166.0
2850 Male, age 76, both hemispheres 164.4
Periaquaductal grey, lateral
nTPM: 171.6
2272 Male, age 74, both hemispheres 177.8
2053 Male, age 18, unknown 168.8
2140 Male, age 76, both hemispheres 168.4
Pretectal area
nTPM: 176.5
2007 Male, age 72, unknown 192.4
1817 Female, age 42, unknown 189.3
1816 Male, age 51, unknown 185.4
2224 Female, age 72, unknown 185.2
2316 Male, age 76, right hemisphere 178.4
1944 Female, age 72, unknown 175.2
2273 Male, age 74, both hemispheres 173.4
1815 Male, age 53, unknown 172.4
2825 Male, age 18, unknown 168.0
2667 Female, age 75, unknown 162.1
2407 Male, age 75, both hemispheres 159.3
Red nucleus
nTPM: 186.7
2503 Female, age 72, unknown 228.5
2769 Male, age 72, unknown 195.4
2227 Male, age 72, unknown 195.0
2785 Male, age 18, unknown 193.0
1904 Male, age 53, unknown 188.5
1865 Male, age 51, unknown 187.4
1821 Female, age 72, unknown 186.6
2725 Female, age 75, unknown 181.2
2584 Male, age 75, left hemisphere 178.1
1954 Female, age 42, unknown 173.6
2588 Male, age 74, left hemisphere 173.1
2823 Male, age 76, right hemisphere 159.7
Substantia nigra
nTPM: 182.9
1851 Male, age 51, unknown 208.9
1916 Female, age 42, unknown 202.2
2699 Male, age 18, unknown 189.5
1889 Female, age 72, unknown 184.3
2665 Male, age 74, both hemispheres 184.3
2590 Female, age 75, unknown 178.5
1941 Male, age 53, unknown 176.9
2409 Female, age 72, unknown 169.9
2583 Male, age 75, right hemisphere 167.6
2241 Male, age 72, unknown 166.7
Superior colliculus
nTPM: 180.9
1796 Male, age 53, unknown 192.3
2587 Male, age 74, left hemisphere 189.7
1913 Female, age 42, unknown 188.4
2668 Female, age 75, unknown 187.8
2261 Male, age 18, unknown 186.2
1995 Male, age 72, unknown 183.3
2087 Female, age 72, unknown 181.5
2664 Male, age 75, both hemispheres 168.5
1895 Male, age 76, right hemisphere 168.1
1839 Male, age 51, unknown 163.3
Ventral tegmental area
nTPM: 187.6
1915 Female, age 42, unknown 199.5
2223 Female, age 72, unknown 195.1
1942 Male, age 51, unknown 186.7
2410 Female, age 72, unknown 186.6
2218 Male, age 76, both hemispheres 179.0
2021 Male, age 53, unknown 178.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 579.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 579.7
Samples: 139

Max nTPM: 1320.8
Min nTPM: 222.0
Std nTPM: 176.0
Median nTPM: 555.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1320.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1305.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1007.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1001.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 946.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 937.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 915.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 915.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 847.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 845.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 812.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 803.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 799.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 798.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 779.7
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 766.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 750.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 749.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 742.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 740.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 740.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 733.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 732.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 729.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 700.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 700.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 697.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 696.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 689.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 679.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 672.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 670.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 665.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 664.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 660.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 657.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 656.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 653.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 650.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 648.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 644.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 643.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 643.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 642.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 641.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 640.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 639.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 633.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 630.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 624.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 623.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 616.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 615.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 613.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 611.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 608.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 607.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 603.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 601.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 600.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 598.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 582.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 581.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 578.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 570.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 569.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 560.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 559.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 556.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 555.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 553.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 553.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 549.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 537.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 537.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 534.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 531.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 531.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 526.4
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 524.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 520.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 516.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 516.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 514.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 509.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 507.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 503.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 502.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 500.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 498.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 497.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 492.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 492.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 491.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 489.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 484.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 482.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 478.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 476.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 476.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 467.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 465.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 462.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 462.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 460.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 460.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 457.2
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 453.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 449.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 447.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 446.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 446.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 439.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 431.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 431.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 430.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 426.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 423.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 416.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 415.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 415.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 413.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 403.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 399.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 398.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 391.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 390.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 384.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 363.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 354.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 354.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 339.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 334.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 329.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 327.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 305.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 279.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 264.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 222.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 177.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 177.7
FF:10158-103A5 76 years, female 177.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 324.4
Pig sample Sample description nTPM
Midbrain
nTPM: 288.1
Samples: 4

Max nTPM: 407.0
Min nTPM: 209.5
Sample A Female 407.0
Sample B Female 292.7
Sample C Male 243.3
Sample D Male 209.5
Periaqueductal gray
nTPM: 226.3
Samples: 3

Max nTPM: 246.7
Min nTPM: 206.3
Sample B Female 225.8
Sample C Male 246.7
Sample D Male 206.3
Substantia nigra
nTPM: 292.0
Samples: 4

Max nTPM: 365.4
Min nTPM: 249.6
Sample A Female 365.4
Sample B Female 294.4
Sample C Male 249.6
Sample D Male 258.7
Superior colliculi
nTPM: 324.5
Samples: 4

Max nTPM: 392.4
Min nTPM: 266.2
Sample A Female 369.8
Sample B Female 392.4
Sample C Male 269.4
Sample D Male 266.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 473.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 473.1
Samples: 4

Max nTPM: 532.1
Min nTPM: 422.1
Sample A Male 532.1
Sample B Male 459.5
Sample C Female 422.1
Sample D Female 478.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 12.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 12.7
69818338 Antisense, RP_050510_04_H06, Mouse strain C57BL/6J (56 days, male) 12.9
74749928 Antisense, RP_060220_04_F02, Mouse strain C57BL/6J (56 days, male) 12.6

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