Expression of RPL8 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 1656.74

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

5-year survival highⁱ N/A

5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

1519.7

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	6299.2
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	4800.6
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	3786.4
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	3776.8
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	3431.5
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	3381.0
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	3192.7
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	3183.7
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	3168.3
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	2995.1
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	2967.6
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	2904.5
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	2684.8
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	2505.7
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	2489.4
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	2464.2
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	2462.8
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	2458.4
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	2392.1
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	2372.9
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	2301.4
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	2259.7
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	2210.6
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	2207.7
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	2174.4
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	2164.8
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	2162.5
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	2148.0
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	2109.4
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	2097.5
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	2070.8
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	2023.9
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	2009.3
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	2003.6
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	1983.9
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	1910.8
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	1876.6
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	1853.2
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	1843.4
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	1838.6
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	1837.5
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	1829.6
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	1807.4
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	1766.4
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	1756.6
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	1751.4
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	1695.2
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	1673.2
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	1660.1
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	1653.4
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	1643.9
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	1621.5
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	1605.5
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	1595.9
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	1588.0
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	1581.1
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	1544.1
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	1539.9
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	1539.2
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	1524.9
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	1511.8
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	1504.0
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	1497.6
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	1484.4
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	1470.4
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	1468.7
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	1435.1
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	1426.0
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	1422.2
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	1409.7
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	1406.7
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	1405.9
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	1395.9
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	1376.8
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	1369.0
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	1361.5
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	1358.7
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	1329.1
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	1317.4
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	1313.7
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	1293.9
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	1290.7
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	1284.4
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	1282.6
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	1280.4
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	1265.1
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	1259.7
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	1246.0
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	1244.0
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	1242.1
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	1230.7
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	1229.9
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	1208.6
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	1183.0
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	1182.3
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	1151.9
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	1146.8
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	1139.7
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	1109.1
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	1106.4
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	1084.3
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	1081.7
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	1073.6
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	1068.5
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	1042.8
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	1039.5
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	1033.6
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	1027.4
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	1025.3
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	1019.9
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	1011.2
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	1006.9
TCGA-CL-4957-01A	79 years, female, dead, 425 days	1006.7
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	1003.2
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	1001.7
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	997.2
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	996.7
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	993.2
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	988.9
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	988.0
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	984.7
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	982.0
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	974.3
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	966.0
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	960.4
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	955.8
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	954.3
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	945.0
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	941.5
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	914.8
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	897.2
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	882.4
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	872.9
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	866.1
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	861.1
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	859.5
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	851.9
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	835.4
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	821.6
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	818.7
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	792.4
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	787.7
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	755.6
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	751.5
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	731.0
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	717.6
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	717.0
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	711.3
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	700.0
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	670.2
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	661.7
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	607.4
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	574.5
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	574.4
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	541.7
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	536.9
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	468.7
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	442.0
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	439.8
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