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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:211.1 nTPM
HPA:211.1 nTPM
GTEx:240.0 nTPM
FANTOM5:165.0 Scaled Tags Per Million
Pig:264.6 nTPM
Mouse:663.9 nTPM
Allen mouse:7.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 211.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 192.5
1827 Male, age 72, unknown 216.5
2411 Female, age 72, unknown 199.9
2666 Male, age 74, left hemisphere 198.8
2019 Male, age 18, unknown 197.3
2219 Male, age 76, both hemispheres 197.1
1870 Female, age 42, unknown 194.3
2828 Female, age 72, unknown 186.2
2586 Male, age 75, left hemisphere 186.0
1833 Male, age 53, unknown 177.7
1830 Male, age 51, unknown 171.1
Dorsal raphe nucleus
nTPM: 196.8
2298 Female, age 72, unknown 229.8
2047 Male, age 72, unknown 202.1
2750 Male, age 76, both hemispheres 196.4
1828 Male, age 53, unknown 191.4
2016 Female, age 72, unknown 164.3
Inferior colliculus
nTPM: 189.6
2097 Female, age 72, unknown 205.8
1848 Female, age 42, unknown 187.6
1890 Male, age 53, unknown 187.3
2849 Male, age 72, unknown 177.6
Median raphe nucleus
nTPM: 206.5
2220 Male, age 76, midline 206.5
Pedunculopontine tegmental nucleus
nTPM: 203.7
1921 Female, age 85, both hemispheres 210.8
2334 Male, age 80, both hemispheres 203.8
2338 Male, age 61, both hemispheres 196.4
Periaquaductal grey, anterior
nTPM: 205.8
1795 Male, age 51, unknown 217.6
1947 Male, age 18, unknown 209.1
2502 Female, age 75, unknown 190.7
Periaquaductal grey, dorsal
nTPM: 182.0
1831 Male, age 72, unknown 190.8
1840 Male, age 53, unknown 188.2
2850 Male, age 76, both hemispheres 176.4
2464 Female, age 72, unknown 172.5
Periaquaductal grey, lateral
nTPM: 177.5
2053 Male, age 18, unknown 185.0
2272 Male, age 74, both hemispheres 180.5
2140 Male, age 76, both hemispheres 166.9
Pretectal area
nTPM: 211.1
1816 Male, age 51, unknown 251.3
2007 Male, age 72, unknown 239.4
1944 Female, age 72, unknown 238.1
1817 Female, age 42, unknown 232.1
1815 Male, age 53, unknown 211.9
2667 Female, age 75, unknown 211.4
2224 Female, age 72, unknown 205.6
2273 Male, age 74, both hemispheres 193.6
2825 Male, age 18, unknown 183.9
2407 Male, age 75, both hemispheres 183.1
2316 Male, age 76, right hemisphere 171.8
Red nucleus
nTPM: 186.8
1821 Female, age 72, unknown 208.6
2725 Female, age 75, unknown 204.7
2785 Male, age 18, unknown 198.0
2588 Male, age 74, left hemisphere 193.5
2503 Female, age 72, unknown 189.7
2584 Male, age 75, left hemisphere 181.4
1954 Female, age 42, unknown 181.2
2227 Male, age 72, unknown 178.1
2769 Male, age 72, unknown 178.1
1904 Male, age 53, unknown 177.1
1865 Male, age 51, unknown 176.9
2823 Male, age 76, right hemisphere 174.8
Substantia nigra
nTPM: 210.5
1916 Female, age 42, unknown 244.6
1941 Male, age 53, unknown 234.9
1889 Female, age 72, unknown 233.1
1851 Male, age 51, unknown 226.5
2241 Male, age 72, unknown 205.4
2665 Male, age 74, both hemispheres 202.9
2409 Female, age 72, unknown 195.9
2699 Male, age 18, unknown 188.6
2583 Male, age 75, right hemisphere 186.8
2590 Female, age 75, unknown 186.5
Superior colliculus
nTPM: 193.6
1796 Male, age 53, unknown 216.2
2087 Female, age 72, unknown 209.3
2668 Female, age 75, unknown 207.7
2261 Male, age 18, unknown 206.1
2587 Male, age 74, left hemisphere 193.9
1895 Male, age 76, right hemisphere 186.6
1913 Female, age 42, unknown 185.3
1839 Male, age 51, unknown 182.6
2664 Male, age 75, both hemispheres 181.2
1995 Male, age 72, unknown 167.3
Ventral tegmental area
nTPM: 203.7
2218 Male, age 76, both hemispheres 220.4
2410 Female, age 72, unknown 219.9
1915 Female, age 42, unknown 217.6
2223 Female, age 72, unknown 192.6
1942 Male, age 51, unknown 190.5
2021 Male, age 53, unknown 181.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 240.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 240.0
Samples: 139

Max nTPM: 720.0
Min nTPM: 140.7
Std nTPM: 87.0
Median nTPM: 210.7
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 720.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 592.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 469.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 451.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 441.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 429.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 392.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 387.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 386.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 368.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 364.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 364.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 360.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 354.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 351.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 351.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 349.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 348.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 346.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 342.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 333.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 321.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 319.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 309.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 299.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 294.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 290.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 290.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 288.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 286.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 285.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 285.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 274.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 271.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 269.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 265.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 264.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 262.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 257.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 255.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 255.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 254.0
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 253.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 249.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 244.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 242.1
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 240.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 240.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 239.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 239.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 238.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 237.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 235.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 234.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 232.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 232.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 231.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 228.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 228.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 225.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 225.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 224.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 218.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 217.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 217.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 216.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 215.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 214.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 211.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 210.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 207.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 204.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 203.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 201.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 199.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 197.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 196.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 196.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 195.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 195.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 195.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 195.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 194.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 194.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 193.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 193.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 193.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 193.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 192.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 192.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 192.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 191.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 191.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 191.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 190.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 188.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 188.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 188.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 188.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 187.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 186.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 186.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 186.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 185.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 184.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 184.7
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 184.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 184.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 183.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 183.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 182.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 179.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 179.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 177.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 176.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 175.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 172.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 172.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 171.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 171.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 170.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 169.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 169.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 168.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 167.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 166.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 165.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 163.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 163.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 163.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 161.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 161.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 161.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 161.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 157.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 150.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 150.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 149.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 140.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 165.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 165.0
FF:10158-103A5 76 years, female 165.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 264.6
Pig sample Sample description nTPM
Midbrain
nTPM: 250.6
Samples: 4

Max nTPM: 334.7
Min nTPM: 192.6
Sample A Female 232.0
Sample B Female 192.6
Sample C Male 334.7
Sample D Male 243.1
Periaqueductal gray
nTPM: 182.2
Samples: 3

Max nTPM: 219.0
Min nTPM: 154.1
Sample B Female 173.6
Sample C Male 219.0
Sample D Male 154.1
Substantia nigra
nTPM: 223.9
Samples: 4

Max nTPM: 305.4
Min nTPM: 145.7
Sample A Female 305.4
Sample B Female 178.0
Sample C Male 266.4
Sample D Male 145.7
Superior colliculi
nTPM: 264.6
Samples: 4

Max nTPM: 324.6
Min nTPM: 209.5
Sample A Female 288.3
Sample B Female 209.5
Sample C Male 324.6
Sample D Male 236.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 663.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 664.0
Samples: 4

Max nTPM: 681.7
Min nTPM: 650.9
Sample A Male 657.1
Sample B Male 650.9
Sample C Female 666.1
Sample D Female 681.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 7.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.1
101 Antisense, RP_Baylor_102629, Mouse strain C57BL/6J (56 days, male) 7.1

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