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  • ATP1A1
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:103.5 nTPM
HPA:103.5 nTPM
GTEx:114.7 nTPM
FANTOM5:137.0 Scaled Tags Per Million
Pig:232.6 nTPM
Mouse:127.7 nTPM
Allen mouse:11.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 103.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 79.3
2019 Male, age 18, unknown 118.1
2219 Male, age 76, both hemispheres 85.9
1827 Male, age 72, unknown 85.2
2411 Female, age 72, unknown 83.3
2666 Male, age 74, left hemisphere 74.1
1870 Female, age 42, unknown 71.5
1833 Male, age 53, unknown 70.2
1830 Male, age 51, unknown 69.4
2586 Male, age 75, left hemisphere 68.1
2828 Female, age 72, unknown 67.1
Dorsal raphe nucleus
nTPM: 70.0
2298 Female, age 72, unknown 80.9
2750 Male, age 76, both hemispheres 74.1
2047 Male, age 72, unknown 70.9
1828 Male, age 53, unknown 69.0
2016 Female, age 72, unknown 55.0
Inferior colliculus
nTPM: 88.5
2097 Female, age 72, unknown 98.3
1890 Male, age 53, unknown 91.3
1848 Female, age 42, unknown 87.1
2849 Male, age 72, unknown 77.2
Median raphe nucleus
nTPM: 76.6
2220 Male, age 76, midline 76.6
Pedunculopontine tegmental nucleus
nTPM: 94.1
2334 Male, age 80, both hemispheres 121.3
2338 Male, age 61, both hemispheres 86.1
1921 Female, age 85, both hemispheres 74.9
Periaquaductal grey, anterior
nTPM: 79.4
2502 Female, age 75, unknown 95.9
1795 Male, age 51, unknown 74.0
1947 Male, age 18, unknown 68.3
Periaquaductal grey, dorsal
nTPM: 63.8
2850 Male, age 76, both hemispheres 70.7
1840 Male, age 53, unknown 62.0
2464 Female, age 72, unknown 61.7
1831 Male, age 72, unknown 60.8
Periaquaductal grey, lateral
nTPM: 73.0
2272 Male, age 74, both hemispheres 90.9
2140 Male, age 76, both hemispheres 64.9
2053 Male, age 18, unknown 63.4
Pretectal area
nTPM: 93.6
2007 Male, age 72, unknown 126.7
1816 Male, age 51, unknown 124.5
1817 Female, age 42, unknown 124.2
1944 Female, age 72, unknown 110.2
1815 Male, age 53, unknown 100.2
2273 Male, age 74, both hemispheres 88.8
2407 Male, age 75, both hemispheres 85.2
2667 Female, age 75, unknown 81.2
2825 Male, age 18, unknown 66.8
2224 Female, age 72, unknown 62.3
2316 Male, age 76, right hemisphere 59.7
Red nucleus
nTPM: 86.8
2785 Male, age 18, unknown 112.7
1821 Female, age 72, unknown 112.2
1865 Male, age 51, unknown 87.7
2588 Male, age 74, left hemisphere 86.9
1954 Female, age 42, unknown 86.7
1904 Male, age 53, unknown 86.1
2725 Female, age 75, unknown 84.8
2584 Male, age 75, left hemisphere 83.5
2769 Male, age 72, unknown 77.5
2227 Male, age 72, unknown 76.6
2503 Female, age 72, unknown 75.6
2823 Male, age 76, right hemisphere 71.7
Substantia nigra
nTPM: 103.5
1941 Male, age 53, unknown 136.0
1916 Female, age 42, unknown 132.0
1851 Male, age 51, unknown 111.6
1889 Female, age 72, unknown 108.0
2241 Male, age 72, unknown 107.9
2665 Male, age 74, both hemispheres 93.7
2409 Female, age 72, unknown 92.5
2583 Male, age 75, right hemisphere 88.0
2590 Female, age 75, unknown 87.1
2699 Male, age 18, unknown 77.7
Superior colliculus
nTPM: 81.6
2087 Female, age 72, unknown 98.1
2261 Male, age 18, unknown 94.8
2587 Male, age 74, left hemisphere 91.4
2668 Female, age 75, unknown 87.3
1796 Male, age 53, unknown 84.9
1895 Male, age 76, right hemisphere 79.6
1913 Female, age 42, unknown 73.6
1995 Male, age 72, unknown 73.0
1839 Male, age 51, unknown 70.7
2664 Male, age 75, both hemispheres 62.9
Ventral tegmental area
nTPM: 87.0
2410 Female, age 72, unknown 111.0
1915 Female, age 42, unknown 96.1
2218 Male, age 76, both hemispheres 89.1
2223 Female, age 72, unknown 88.6
1942 Male, age 51, unknown 76.1
2021 Male, age 53, unknown 61.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 114.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 114.7
Samples: 139

Max nTPM: 574.9
Min nTPM: 27.0
Std nTPM: 63.4
Median nTPM: 101.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 574.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 351.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 322.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 241.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 225.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 218.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 216.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 208.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 207.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 185.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 182.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 181.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 180.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 178.6
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 177.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 172.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 170.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 168.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 168.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 167.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 156.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 154.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 154.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 153.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 148.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 148.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 147.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 147.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 145.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 144.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 134.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 133.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 132.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 132.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 131.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 130.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 130.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 129.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 128.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 128.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 126.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 126.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 126.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 124.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 123.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 123.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 122.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 120.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 120.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 118.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 118.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 117.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 117.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 115.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 112.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 111.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 111.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 109.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 109.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 109.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 108.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 108.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 107.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 106.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 105.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 105.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 103.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 102.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 101.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 101.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 101.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 99.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 98.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 97.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 97.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 96.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 95.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 93.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 93.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 91.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 91.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 90.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 89.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 89.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 89.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 87.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 87.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 87.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 86.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 85.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 85.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 84.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 84.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 84.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 83.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 83.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 83.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 82.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 82.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 81.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 79.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 78.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 78.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 77.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 77.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 77.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 77.4
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 76.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 76.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 76.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 75.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 75.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 73.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 72.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 71.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 70.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 69.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 68.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 66.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 66.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 65.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 64.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 64.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 63.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 63.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 62.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 61.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 58.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 56.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 55.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 55.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 55.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 53.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 53.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 51.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 49.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 42.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 34.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 27.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 137.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 137.0
FF:10158-103A5 76 years, female 137.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 232.6
Pig sample Sample description nTPM
Midbrain
nTPM: 232.6
Samples: 4

Max nTPM: 296.2
Min nTPM: 102.1
Sample A Female 290.3
Sample B Female 102.1
Sample C Male 296.2
Sample D Male 241.8
Periaqueductal gray
nTPM: 107.4
Samples: 3

Max nTPM: 133.7
Min nTPM: 93.3
Sample B Female 93.3
Sample C Male 133.7
Sample D Male 95.2
Substantia nigra
nTPM: 145.6
Samples: 4

Max nTPM: 195.6
Min nTPM: 100.5
Sample A Female 195.6
Sample B Female 100.5
Sample C Male 151.8
Sample D Male 134.6
Superior colliculi
nTPM: 220.8
Samples: 4

Max nTPM: 276.8
Min nTPM: 148.4
Sample A Female 253.7
Sample B Female 148.4
Sample C Male 276.8
Sample D Male 204.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 127.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 127.7
Samples: 4

Max nTPM: 133.1
Min nTPM: 119.9
Sample A Male 119.9
Sample B Male 126.3
Sample C Female 133.1
Sample D Female 131.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 11.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 11.3
71836844 Antisense, RP_051017_02_C07, Mouse strain C57BL/6J (56 days, male) 14.7
100055054 Antisense, RP_080110_01_A05, Mouse strain C57BL/6J (56 days, male) 13.9
100055069 Antisense, RP_080110_01_A05, Mouse strain C57BL/6J (56 days, male) 13.2
100055045 Antisense, RP_080110_01_A05, Mouse strain C57BL/6J (56 days, male) 13.2
68157413 Antisense, RP_041116_02_F06, Mouse strain C57BL/6J (56 days, male) 5.2

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