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IGFBP7
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BRAIN PONS Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Pons
PONS - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

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No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
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Consensus:146.4 nTPM
HPA:146.4 nTPM
FANTOM5:464.9 Scaled Tags Per Million
Pig:83.0 nTPM
Allen mouse:2.6 Expression energy

PONS - HPA Brain RNA-seq
Max nTPM 146.4
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 96.5
2301 Female, age 85, both hemispheres 107.5
2188 Female, age 91, both hemispheres 98.7
2090 Male, age 80, both hemispheres 95.7
1984 Male, age 76, both hemispheres 83.9
Dorsal cochlear nucleus
nTPM: 115.3
2802 Male, age 74, right hemisphere 135.1
2370 Male, age 61, both hemispheres 129.2
2378 Male, age 80, both hemispheres 112.7
2058 Male, age 76, both hemispheres 104.1
2187 Female, age 91, both hemispheres 95.4
Dorsal tegmental nucleus
nTPM: 129.8
2358 Male, age 61, both hemispheres 160.6
2083 Male, age 80, both hemispheres 121.2
1936 Male, age 76, left hemisphere 119.9
2326 Male, age 74, both hemispheres 117.4
Dorsolateral tegmental area
nTPM: 142.1
2337 Male, age 61, both hemispheres 245.6
2654 Male, age 80, both hemispheres 127.5
2751 Female, age 85, both hemispheres 122.2
2360 Male, age 74, both hemispheres 118.7
2141 Male, age 76, both hemispheres 96.3
Kolliker-Fuse nucleus
nTPM: 106.1
2315 Male, age 76, right hemisphere 117.4
2163 Male, age 80, both hemispheres 110.7
2793 Female, age 91, left hemisphere 90.1
Lateral lemniscal nuclei
nTPM: 108.4
2746 Female, age 85, left hemisphere 153.2
2453 Male, age 74, right hemisphere 102.4
2320 Female, age 91, left hemisphere 96.5
2169 Male, age 76, both hemispheres 95.2
2036 Male, age 80, both hemispheres 94.5
Lateral parabrachial nucleus
nTPM: 112.2
2790 Male, age 61, both hemispheres 123.7
2139 Female, age 85, right hemisphere 112.1
2013 Male, age 80, both hemispheres 108.7
2792 Male, age 76, both hemispheres 104.2
Lateral vestibular nucleus
nTPM: 108.6
2184 Male, age 76, both hemispheres 112.1
2311 Male, age 80, both hemispheres 105.0
Locus coeruleus
nTPM: 93.8
2317 Female, age 72, unknown 116.4
1980 Male, age 76, both hemispheres 109.3
2123 Female, age 91, both hemispheres 89.7
2162 Male, age 80, both hemispheres 88.2
2720 Male, age 74, both hemispheres 86.5
2788 Male, age 74, unknown 84.4
2014 Male, age 55, unknown 82.3
Medial olivary nucleus
nTPM: 146.4
1962 Male, age 76, both hemispheres 181.8
1943 Male, age 61, both hemispheres 163.9
2138 Female, age 91, both hemispheres 120.5
2851 Male, age 80, both hemispheres 119.3
Medial parabrachial nucleus
nTPM: 113.6
2156 Male, age 61, both hemispheres 131.8
2463 Female, age 85, right hemisphere 116.6
2786 Male, age 76, both hemispheres 110.9
2170 Female, age 91, both hemispheres 109.8
2854 Male, age 80, both hemispheres 99.0
Medial periolivary nuclei
nTPM: 100.3
2063 Male, age 76, both hemispheres 106.8
2081 Male, age 80, both hemispheres 104.6
2791 Male, age 74, right hemisphere 100.9
2171 Female, age 85, both hemispheres 98.1
2458 Female, age 91, both hemispheres 91.1
Motor facial nucleus
nTPM: 104.8
2795 Female, age 91, both hemispheres 126.1
2126 Male, age 61, both hemispheres 113.5
2062 Male, age 76, both hemispheres 111.7
2327 Male, age 80, both hemispheres 96.9
2365 Male, age 74, right hemisphere 94.6
2697 Female, age 85, both hemispheres 85.9
Motor trigeminal nucleus
nTPM: 116.1
2335 Male, age 61, both hemispheres 149.3
2309 Male, age 76, both hemispheres 120.2
2560 Male, age 74, both hemispheres 108.8
2079 Male, age 80, both hemispheres 106.6
2321 Female, age 91, both hemispheres 95.5
Nuclei of the trapezoid body
nTPM: 100.8
1983 Male, age 76, both hemispheres 116.1
2735 Female, age 85, both hemispheres 104.5
2368 Female, age 91, both hemispheres 100.8
2166 Male, age 80, both hemispheres 98.8
2159 Male, age 61, both hemispheres 83.5
Paramedian reticular nucleus
nTPM: 111.8
2313 Male, age 61, both hemispheres 120.7
2057 Male, age 80, both hemispheres 118.5
2052 Male, age 76, both hemispheres 110.0
2050 Female, age 85, both hemispheres 98.0
Pontine nuclei
nTPM: 104.3
2115 Male, age 80, left hemisphere 122.8
1968 Male, age 76, left hemisphere 120.4
2787 Female, age 85, both hemispheres 110.1
2319 Female, age 91, both hemispheres 107.0
2109 Female, age 72, unknown 102.4
2454 Male, age 74, left hemisphere 98.3
1863 Male, age 55, unknown 92.0
2727 Male, age 61, right hemisphere 81.0
Pontine raphe nucleus
nTPM: 95.6
2853 Male, age 76, midline 99.3
2122 Female, age 85, midline 91.9
Posteroventral cochlear nucleus
nTPM: 115.2
2371 Male, age 61, both hemispheres 138.5
2070 Male, age 76, both hemispheres 124.7
2135 Female, age 91, both hemispheres 108.9
2341 Male, age 80, both hemispheres 102.9
2752 Female, age 85, both hemispheres 101.0
Principal sensory trigeminal nucleus
nTPM: 98.1
2324 Male, age 76, both hemispheres 120.0
2008 Male, age 80, left hemisphere 100.0
2367 Female, age 91, left hemisphere 89.8
2158 Male, age 61, both hemispheres 82.6
Reticular pontine nucleus, caudal
nTPM: 106.8
2092 Male, age 76, both hemispheres 114.1
2332 Male, age 80, right hemisphere 111.8
2559 Male, age 74, both hemispheres 106.9
2457 Female, age 91, both hemispheres 94.6
Reticular pontine nucleus, oral
nTPM: 101.4
1939 Male, age 80, both hemispheres 119.8
2012 Female, age 85, both hemispheres 105.0
2167 Male, age 76, both hemispheres 100.5
2366 Female, age 91, both hemispheres 96.8
2361 Male, age 74, both hemispheres 84.7
Reticulotegmental nucleus
nTPM: 115.8
2333 Male, age 80, both hemispheres 131.5
2452 Male, age 74, both hemispheres 122.2
2325 Male, age 76, both hemispheres 107.8
2322 Female, age 91, both hemispheres 101.7
Spinal trigeminal nucleus, oral
nTPM: 109.6
2164 Male, age 80, both hemispheres 116.1
1978 Male, age 76, both hemispheres 108.6
2737 Female, age 85, both hemispheres 104.2
Subcoeruleus area
nTPM: 105.4
2451 Male, age 74, both hemispheres 121.4
2369 Female, age 85, left hemisphere 116.7
1958 Male, age 80, both hemispheres 104.2
2323 Female, age 91, left hemisphere 94.2
2089 Male, age 76, left hemisphere 90.4
Superior olive
nTPM: 101.7
2329 Male, age 80, right hemisphere 110.6
2364 Male, age 74, right hemisphere 109.8
2020 Male, age 76, both hemispheres 104.7
2561 Female, age 91, both hemispheres 96.5
1875 Female, age 85, both hemispheres 87.2
Superior vestibular nucleus
nTPM: 110.1
2061 Male, age 76, both hemispheres 114.8
2015 Male, age 80, both hemispheres 113.0
2383 Male, age 74, both hemispheres 102.4
Ventral periolivary nuclei
nTPM: 100.3
2165 Male, age 80, both hemispheres 107.5
2023 Male, age 76, both hemispheres 104.0
2130 Female, age 85, both hemispheres 97.9
2794 Female, age 91, left hemisphere 91.8
Ventrolateral tegmental area, A5 NE cell group
nTPM: 113.5
2359 Male, age 61, both hemispheres 139.0
2840 Female, age 85, both hemispheres 116.2
2161 Male, age 80, both hemispheres 111.0
2456 Female, age 91, both hemispheres 107.4
1959 Male, age 76, both hemispheres 106.3
2449 Male, age 74, both hemispheres 101.0

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

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Max Scaled Tags Per Million 464.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 464.9
FF:10182-103D2 60 years, female 490.3
FF:10165-103B3 76 years, female 439.4
Pons
Scaled Tags Per Million: 340.1
FF:10033-101E6 18-54 years, mixed 340.1

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
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Average nTPM 83.0
Pig sample Sample description nTPM
Pons
nTPM: 83.0
Samples: 4

Max nTPM: 132.5
Min nTPM: 56.4
Sample A Female 132.5
Sample B Female 56.4
Sample C Male 60.6
Sample D Male 82.3

PONS - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

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Max Expression energy 2.6
Allen experiment id Experiment description Expression energy
Pons
Expression energy: 2.6
81654139 Antisense, RP_090205_01_B05, Mouse strain C57BL/6J (56 days, male) 2.6

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.