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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:159.7 nTPM
HPA:159.7 nTPM
GTEx:142.6 nTPM
FANTOM5:132.7 Scaled Tags Per Million
Pig:85.0 nTPM
Mouse:53.3 nTPM
Allen mouse:0.4 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 159.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 152.8
1870 Female, age 42, unknown 162.3
1830 Male, age 51, unknown 156.5
1833 Male, age 53, unknown 156.1
2411 Female, age 72, unknown 155.0
2828 Female, age 72, unknown 153.7
1827 Male, age 72, unknown 153.3
2019 Male, age 18, unknown 151.8
2666 Male, age 74, left hemisphere 149.0
2219 Male, age 76, both hemispheres 148.1
2586 Male, age 75, left hemisphere 142.3
Dorsal raphe nucleus
nTPM: 153.8
2298 Female, age 72, unknown 157.1
2750 Male, age 76, both hemispheres 155.3
1828 Male, age 53, unknown 153.4
2047 Male, age 72, unknown 152.6
2016 Female, age 72, unknown 150.6
Inferior colliculus
nTPM: 152.3
2849 Male, age 72, unknown 155.3
2097 Female, age 72, unknown 152.5
1848 Female, age 42, unknown 150.7
1890 Male, age 53, unknown 150.6
Median raphe nucleus
nTPM: 159.7
2220 Male, age 76, midline 159.7
Pedunculopontine tegmental nucleus
nTPM: 159.5
2338 Male, age 61, both hemispheres 166.5
2334 Male, age 80, both hemispheres 159.3
1921 Female, age 85, both hemispheres 152.7
Periaquaductal grey, anterior
nTPM: 150.4
1947 Male, age 18, unknown 152.5
2502 Female, age 75, unknown 149.6
1795 Male, age 51, unknown 149.3
Periaquaductal grey, dorsal
nTPM: 151.9
2850 Male, age 76, both hemispheres 160.9
1831 Male, age 72, unknown 151.3
1840 Male, age 53, unknown 148.5
2464 Female, age 72, unknown 146.8
Periaquaductal grey, lateral
nTPM: 153.8
2272 Male, age 74, both hemispheres 157.8
2140 Male, age 76, both hemispheres 153.1
2053 Male, age 18, unknown 150.5
Pretectal area
nTPM: 153.7
2273 Male, age 74, both hemispheres 158.8
1815 Male, age 53, unknown 157.9
1817 Female, age 42, unknown 157.9
2667 Female, age 75, unknown 157.3
2224 Female, age 72, unknown 154.8
2825 Male, age 18, unknown 153.7
1944 Female, age 72, unknown 152.5
2407 Male, age 75, both hemispheres 151.4
2007 Male, age 72, unknown 150.2
1816 Male, age 51, unknown 148.3
2316 Male, age 76, right hemisphere 147.2
Red nucleus
nTPM: 157.1
2823 Male, age 76, right hemisphere 164.9
1821 Female, age 72, unknown 163.3
1954 Female, age 42, unknown 160.9
1904 Male, age 53, unknown 160.7
1865 Male, age 51, unknown 159.4
2725 Female, age 75, unknown 158.6
2227 Male, age 72, unknown 156.9
2503 Female, age 72, unknown 155.1
2769 Male, age 72, unknown 154.9
2785 Male, age 18, unknown 154.1
2584 Male, age 75, left hemisphere 151.7
2588 Male, age 74, left hemisphere 144.4
Substantia nigra
nTPM: 155.1
2699 Male, age 18, unknown 167.7
1916 Female, age 42, unknown 159.3
2665 Male, age 74, both hemispheres 155.9
1851 Male, age 51, unknown 155.2
1889 Female, age 72, unknown 155.0
1941 Male, age 53, unknown 154.8
2241 Male, age 72, unknown 154.4
2409 Female, age 72, unknown 152.2
2590 Female, age 75, unknown 149.5
2583 Male, age 75, right hemisphere 146.9
Superior colliculus
nTPM: 153.0
1913 Female, age 42, unknown 159.9
2587 Male, age 74, left hemisphere 158.7
1839 Male, age 51, unknown 155.9
1895 Male, age 76, right hemisphere 155.0
1995 Male, age 72, unknown 155.0
2668 Female, age 75, unknown 153.5
1796 Male, age 53, unknown 151.4
2087 Female, age 72, unknown 148.3
2261 Male, age 18, unknown 146.8
2664 Male, age 75, both hemispheres 145.8
Ventral tegmental area
nTPM: 155.0
2218 Male, age 76, both hemispheres 157.6
1915 Female, age 42, unknown 157.5
2410 Female, age 72, unknown 156.9
2223 Female, age 72, unknown 156.0
1942 Male, age 51, unknown 151.7
2021 Male, age 53, unknown 150.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 142.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 142.6
Samples: 139

Max nTPM: 361.5
Min nTPM: 66.4
Std nTPM: 41.6
Median nTPM: 133.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 361.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 295.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 273.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 246.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 236.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 231.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 224.4
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 213.1
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 206.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 204.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 201.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 199.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 194.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 192.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 191.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 187.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 181.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 176.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 176.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 175.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 174.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 172.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 171.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 171.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 171.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 167.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 167.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 167.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 166.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 166.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 165.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 164.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 164.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 162.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 162.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 161.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 161.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 160.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 159.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 159.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 159.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 157.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 156.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 154.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 150.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 150.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 149.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 148.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 148.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 147.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 145.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 144.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 144.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 143.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 143.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 143.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 141.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 141.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 140.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 139.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 139.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 139.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 138.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 137.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 136.2
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 136.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 135.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 135.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 134.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 133.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 133.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 132.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 132.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 132.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 132.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 130.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 130.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 130.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 129.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 128.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 127.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 127.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 127.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 126.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 126.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 125.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 123.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 123.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 122.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 122.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 122.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 122.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 121.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 121.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 121.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 120.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 120.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 120.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 120.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 116.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 116.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 116.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 115.7
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 115.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 115.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 114.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 114.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 114.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 113.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 112.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 110.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 110.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 109.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 109.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 109.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 107.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 107.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 105.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 105.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 104.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 103.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 103.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 102.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 101.8
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 100.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 99.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 99.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 98.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 97.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 97.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 97.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 96.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 96.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 94.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 93.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 92.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 91.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 87.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 66.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 132.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 132.7
FF:10158-103A5 76 years, female 132.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 85.0
Pig sample Sample description nTPM
Midbrain
nTPM: 76.3
Samples: 4

Max nTPM: 100.3
Min nTPM: 65.4
Sample A Female 100.3
Sample B Female 73.4
Sample C Male 65.4
Sample D Male 66.2
Periaqueductal gray
nTPM: 71.4
Samples: 3

Max nTPM: 77.9
Min nTPM: 66.8
Sample B Female 69.5
Sample C Male 77.9
Sample D Male 66.8
Substantia nigra
nTPM: 80.6
Samples: 4

Max nTPM: 90.2
Min nTPM: 75.1
Sample A Female 90.2
Sample B Female 75.1
Sample C Male 75.7
Sample D Male 81.4
Superior colliculi
nTPM: 85.0
Samples: 4

Max nTPM: 95.2
Min nTPM: 76.8
Sample A Female 95.2
Sample B Female 88.2
Sample C Male 79.8
Sample D Male 76.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 53.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 53.3
Samples: 4

Max nTPM: 56.7
Min nTPM: 49.3
Sample A Male 53.4
Sample B Male 56.7
Sample C Female 49.3
Sample D Female 53.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.4
67767459 Antisense, RP_040916_02_A09, Mouse strain C57BL/6J (56 days, male) 0.4

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