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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:182.8 nTPM
HPA:182.8 nTPM
GTEx:35.5 nTPM
FANTOM5:395.9 Scaled Tags Per Million
Pig:165.3 nTPM
Mouse:72.0 nTPM
Allen mouse:2.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 182.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 165.2
2828 Female, age 72, unknown 194.2
1870 Female, age 42, unknown 184.1
2586 Male, age 75, left hemisphere 174.5
1830 Male, age 51, unknown 170.5
1833 Male, age 53, unknown 170.2
2411 Female, age 72, unknown 161.1
2019 Male, age 18, unknown 158.1
1827 Male, age 72, unknown 154.7
2666 Male, age 74, left hemisphere 143.6
2219 Male, age 76, both hemispheres 141.0
Dorsal raphe nucleus
nTPM: 153.4
2016 Female, age 72, unknown 176.2
2750 Male, age 76, both hemispheres 174.7
1828 Male, age 53, unknown 158.6
2047 Male, age 72, unknown 129.5
2298 Female, age 72, unknown 127.9
Inferior colliculus
nTPM: 149.8
2849 Male, age 72, unknown 157.1
1848 Female, age 42, unknown 154.7
1890 Male, age 53, unknown 145.9
2097 Female, age 72, unknown 141.6
Median raphe nucleus
nTPM: 125.4
2220 Male, age 76, midline 125.4
Pedunculopontine tegmental nucleus
nTPM: 129.5
2334 Male, age 80, both hemispheres 139.0
1921 Female, age 85, both hemispheres 135.8
2338 Male, age 61, both hemispheres 113.5
Periaquaductal grey, anterior
nTPM: 157.0
2502 Female, age 75, unknown 172.6
1795 Male, age 51, unknown 152.5
1947 Male, age 18, unknown 145.9
Periaquaductal grey, dorsal
nTPM: 146.5
2464 Female, age 72, unknown 157.0
1831 Male, age 72, unknown 144.7
2850 Male, age 76, both hemispheres 142.9
1840 Male, age 53, unknown 141.4
Periaquaductal grey, lateral
nTPM: 153.6
2053 Male, age 18, unknown 161.7
2140 Male, age 76, both hemispheres 152.6
2272 Male, age 74, both hemispheres 146.6
Pretectal area
nTPM: 157.9
2667 Female, age 75, unknown 183.7
2316 Male, age 76, right hemisphere 183.0
2273 Male, age 74, both hemispheres 164.5
2224 Female, age 72, unknown 163.5
1815 Male, age 53, unknown 160.5
2825 Male, age 18, unknown 155.9
2407 Male, age 75, both hemispheres 155.7
1817 Female, age 42, unknown 149.4
1944 Female, age 72, unknown 145.6
1816 Male, age 51, unknown 138.8
2007 Male, age 72, unknown 135.8
Red nucleus
nTPM: 182.8
2227 Male, age 72, unknown 208.9
2769 Male, age 72, unknown 207.9
1904 Male, age 53, unknown 200.7
2503 Female, age 72, unknown 198.6
1865 Male, age 51, unknown 194.9
1954 Female, age 42, unknown 187.5
2823 Male, age 76, right hemisphere 184.8
1821 Female, age 72, unknown 179.8
2785 Male, age 18, unknown 178.8
2588 Male, age 74, left hemisphere 162.9
2725 Female, age 75, unknown 155.6
2584 Male, age 75, left hemisphere 132.7
Substantia nigra
nTPM: 146.9
2699 Male, age 18, unknown 170.5
1851 Male, age 51, unknown 164.9
2409 Female, age 72, unknown 154.8
1916 Female, age 42, unknown 149.3
2590 Female, age 75, unknown 148.3
1889 Female, age 72, unknown 148.0
2583 Male, age 75, right hemisphere 146.9
2665 Male, age 74, both hemispheres 132.4
2241 Male, age 72, unknown 128.4
1941 Male, age 53, unknown 125.5
Superior colliculus
nTPM: 168.5
1995 Male, age 72, unknown 215.0
1913 Female, age 42, unknown 193.0
2664 Male, age 75, both hemispheres 188.2
1895 Male, age 76, right hemisphere 163.1
1839 Male, age 51, unknown 162.4
1796 Male, age 53, unknown 162.3
2587 Male, age 74, left hemisphere 153.8
2261 Male, age 18, unknown 151.7
2087 Female, age 72, unknown 148.2
2668 Female, age 75, unknown 146.9
Ventral tegmental area
nTPM: 156.1
2410 Female, age 72, unknown 165.1
2021 Male, age 53, unknown 163.5
2223 Female, age 72, unknown 163.1
1915 Female, age 42, unknown 158.2
1942 Male, age 51, unknown 147.1
2218 Male, age 76, both hemispheres 139.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 35.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 35.5
Samples: 139

Max nTPM: 98.9
Min nTPM: 7.0
Std nTPM: 16.5
Median nTPM: 31.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 98.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 96.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 94.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 78.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 75.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 75.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 71.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 69.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 68.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 68.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 63.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 61.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 60.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 60.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 55.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 55.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 53.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 52.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 51.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 50.4
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 49.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 49.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 48.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 47.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 45.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 45.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 45.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 44.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 44.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 43.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 43.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 43.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 43.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 42.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 42.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 41.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 40.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 40.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 40.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 39.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 39.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 37.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 37.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 36.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 36.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 36.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 35.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 35.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 35.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 35.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 35.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 35.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 35.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 35.3
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 35.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 35.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 34.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 34.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 33.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 33.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 33.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 32.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 32.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 32.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 31.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 31.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 31.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 31.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 31.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 31.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 31.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 30.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 30.7
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 30.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 30.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 30.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 30.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 30.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 29.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 29.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 29.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 29.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 28.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 28.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 28.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 27.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 27.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 27.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 27.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 27.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 27.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 27.1
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 26.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 26.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 26.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 26.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 26.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 26.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 25.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 24.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 24.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 24.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 24.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 23.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 23.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 23.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 23.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 23.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 23.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 23.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 22.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 22.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 22.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 22.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 22.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 22.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 22.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 21.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 21.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 21.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 21.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 21.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 21.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 21.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 19.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 19.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 19.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 18.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 18.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 18.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 18.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 18.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 18.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 16.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 16.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 15.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 14.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 14.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 7.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 395.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 395.9
FF:10158-103A5 76 years, female 395.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 165.3
Pig sample Sample description nTPM
Midbrain
nTPM: 165.4
Samples: 4

Max nTPM: 272.0
Min nTPM: 117.4
Sample A Female 272.0
Sample B Female 150.3
Sample C Male 117.4
Sample D Male 121.7
Periaqueductal gray
nTPM: 126.8
Samples: 3

Max nTPM: 144.2
Min nTPM: 117.8
Sample B Female 144.2
Sample C Male 117.8
Sample D Male 118.3
Substantia nigra
nTPM: 155.3
Samples: 4

Max nTPM: 233.0
Min nTPM: 106.8
Sample A Female 152.2
Sample B Female 106.8
Sample C Male 129.1
Sample D Male 233.0
Superior colliculi
nTPM: 128.6
Samples: 4

Max nTPM: 159.8
Min nTPM: 65.7
Sample A Female 151.5
Sample B Female 65.7
Sample C Male 137.3
Sample D Male 159.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 72.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 72.0
Samples: 4

Max nTPM: 74.8
Min nTPM: 66.6
Sample A Male 74.4
Sample B Male 66.6
Sample C Female 72.1
Sample D Female 74.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.5
35 Antisense, RP_Baylor_103286, Mouse strain C57BL/6J (56 days, male) 2.5
36 Antisense, RP_Baylor_103286, Mouse strain C57BL/6J (56 days, male) 0.1

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