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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:130.2 nTPM
HPA:130.2 nTPM
GTEx:151.6 nTPM
FANTOM5:234.2 Scaled Tags Per Million
Pig:89.8 nTPM
Mouse:139.9 nTPM
Allen mouse:3.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 130.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 109.1
1870 Female, age 42, unknown 121.3
1833 Male, age 53, unknown 113.8
2411 Female, age 72, unknown 113.7
1830 Male, age 51, unknown 110.8
2219 Male, age 76, both hemispheres 108.1
2828 Female, age 72, unknown 107.5
2586 Male, age 75, left hemisphere 106.5
2019 Male, age 18, unknown 106.2
1827 Male, age 72, unknown 105.6
2666 Male, age 74, left hemisphere 97.3
Dorsal raphe nucleus
nTPM: 114.5
2298 Female, age 72, unknown 118.3
2750 Male, age 76, both hemispheres 115.8
2047 Male, age 72, unknown 114.9
2016 Female, age 72, unknown 111.7
1828 Male, age 53, unknown 111.6
Inferior colliculus
nTPM: 107.4
2097 Female, age 72, unknown 110.6
1890 Male, age 53, unknown 107.3
2849 Male, age 72, unknown 106.4
1848 Female, age 42, unknown 105.5
Median raphe nucleus
nTPM: 130.2
2220 Male, age 76, midline 130.2
Pedunculopontine tegmental nucleus
nTPM: 116.9
2338 Male, age 61, both hemispheres 125.2
2334 Male, age 80, both hemispheres 113.9
1921 Female, age 85, both hemispheres 111.7
Periaquaductal grey, anterior
nTPM: 106.3
1947 Male, age 18, unknown 107.8
1795 Male, age 51, unknown 106.0
2502 Female, age 75, unknown 105.1
Periaquaductal grey, dorsal
nTPM: 110.0
2850 Male, age 76, both hemispheres 121.3
1840 Male, age 53, unknown 108.5
2464 Female, age 72, unknown 105.3
1831 Male, age 72, unknown 104.9
Periaquaductal grey, lateral
nTPM: 111.0
2140 Male, age 76, both hemispheres 111.2
2272 Male, age 74, both hemispheres 111.0
2053 Male, age 18, unknown 110.8
Pretectal area
nTPM: 110.7
2273 Male, age 74, both hemispheres 121.2
2667 Female, age 75, unknown 118.1
2224 Female, age 72, unknown 115.3
1944 Female, age 72, unknown 112.0
1815 Male, age 53, unknown 110.6
2825 Male, age 18, unknown 109.3
1816 Male, age 51, unknown 108.2
1817 Female, age 42, unknown 108.1
2407 Male, age 75, both hemispheres 106.3
2316 Male, age 76, right hemisphere 106.1
2007 Male, age 72, unknown 102.9
Red nucleus
nTPM: 112.7
1821 Female, age 72, unknown 120.3
1904 Male, age 53, unknown 119.4
1954 Female, age 42, unknown 117.4
1865 Male, age 51, unknown 116.2
2725 Female, age 75, unknown 115.1
2503 Female, age 72, unknown 113.2
2823 Male, age 76, right hemisphere 113.1
2227 Male, age 72, unknown 112.5
2769 Male, age 72, unknown 111.0
2785 Male, age 18, unknown 108.2
2584 Male, age 75, left hemisphere 107.7
2588 Male, age 74, left hemisphere 98.8
Substantia nigra
nTPM: 118.7
2241 Male, age 72, unknown 139.3
1916 Female, age 42, unknown 131.5
2699 Male, age 18, unknown 124.4
1851 Male, age 51, unknown 123.0
2409 Female, age 72, unknown 120.9
1889 Female, age 72, unknown 116.2
1941 Male, age 53, unknown 115.8
2590 Female, age 75, unknown 111.0
2583 Male, age 75, right hemisphere 104.8
2665 Male, age 74, both hemispheres 99.9
Superior colliculus
nTPM: 107.6
2587 Male, age 74, left hemisphere 117.4
1913 Female, age 42, unknown 114.2
1995 Male, age 72, unknown 110.6
2087 Female, age 72, unknown 107.9
2261 Male, age 18, unknown 107.6
1796 Male, age 53, unknown 107.2
2668 Female, age 75, unknown 104.8
2664 Male, age 75, both hemispheres 102.7
1895 Male, age 76, right hemisphere 102.0
1839 Male, age 51, unknown 101.7
Ventral tegmental area
nTPM: 119.3
2223 Female, age 72, unknown 123.6
1915 Female, age 42, unknown 121.6
2410 Female, age 72, unknown 121.4
2218 Male, age 76, both hemispheres 120.4
1942 Male, age 51, unknown 117.6
2021 Male, age 53, unknown 111.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 151.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 151.6
Samples: 139

Max nTPM: 320.2
Min nTPM: 72.5
Std nTPM: 48.5
Median nTPM: 142.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 320.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 318.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 295.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 292.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 279.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 271.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 262.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 260.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 258.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 258.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 253.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 217.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 214.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 213.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 205.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 202.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 196.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 194.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 190.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 189.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 187.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 185.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 184.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 183.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 181.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 180.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 178.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 176.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 175.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 174.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 173.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 173.2
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 173.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 172.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 172.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 171.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 171.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 171.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 168.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 168.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 168.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 167.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 167.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 166.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 165.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 164.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 159.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 158.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 158.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 156.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 154.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 154.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 154.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 153.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 152.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 151.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 151.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 151.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 151.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 150.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 149.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 149.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 148.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 148.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 147.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 147.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 147.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 145.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 145.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 142.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 142.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 139.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 139.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 139.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 139.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 138.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 137.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 134.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 134.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 134.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 132.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 131.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 131.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 129.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 128.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 127.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 126.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 126.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 126.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 126.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 125.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 124.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 123.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 122.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 122.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 122.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 122.3
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 122.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 121.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 121.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 121.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 120.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 120.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 118.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 118.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 118.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 117.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 117.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 114.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 114.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 114.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 114.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 114.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 113.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 113.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 112.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 112.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 110.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 109.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 109.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 107.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 107.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 106.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 106.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 105.3
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 104.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 104.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 103.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 98.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 97.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 97.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 95.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 93.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 89.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 86.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 84.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 81.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 74.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 72.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 234.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 234.2
FF:10158-103A5 76 years, female 234.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 89.8
Pig sample Sample description nTPM
Midbrain
nTPM: 89.8
Samples: 4

Max nTPM: 148.7
Min nTPM: 55.4
Sample A Female 148.7
Sample B Female 66.3
Sample C Male 88.7
Sample D Male 55.4
Periaqueductal gray
nTPM: 57.4
Samples: 3

Max nTPM: 63.6
Min nTPM: 49.9
Sample B Female 49.9
Sample C Male 63.6
Sample D Male 58.8
Substantia nigra
nTPM: 82.6
Samples: 4

Max nTPM: 101.9
Min nTPM: 55.2
Sample A Female 101.9
Sample B Female 55.2
Sample C Male 92.3
Sample D Male 80.8
Superior colliculi
nTPM: 73.2
Samples: 4

Max nTPM: 91.7
Min nTPM: 46.8
Sample A Female 76.1
Sample B Female 46.8
Sample C Male 91.7
Sample D Male 78.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 139.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 139.9
Samples: 4

Max nTPM: 157.4
Min nTPM: 123.0
Sample A Male 157.4
Sample B Male 131.4
Sample C Female 123.0
Sample D Female 147.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.8
385777 Antisense, RP_040625_01_E05, Mouse strain C57BL/6J (56 days, male) 3.8

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