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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:448.3 nTPM
HPA:448.3 nTPM
GTEx:574.4 nTPM
FANTOM5:396.5 Scaled Tags Per Million
Pig:123.4 nTPM
Mouse:623.0 nTPM
Allen mouse:11.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 448.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 408.0
2586 Male, age 75, left hemisphere 433.3
2219 Male, age 76, both hemispheres 418.8
1827 Male, age 72, unknown 417.5
2828 Female, age 72, unknown 408.9
2411 Female, age 72, unknown 406.3
1833 Male, age 53, unknown 404.5
2666 Male, age 74, left hemisphere 403.0
2019 Male, age 18, unknown 400.8
1870 Female, age 42, unknown 400.4
1830 Male, age 51, unknown 386.7
Dorsal raphe nucleus
nTPM: 423.2
2298 Female, age 72, unknown 441.8
2047 Male, age 72, unknown 437.1
1828 Male, age 53, unknown 426.9
2750 Male, age 76, both hemispheres 414.3
2016 Female, age 72, unknown 395.9
Inferior colliculus
nTPM: 406.6
2097 Female, age 72, unknown 412.9
2849 Male, age 72, unknown 412.2
1890 Male, age 53, unknown 408.9
1848 Female, age 42, unknown 392.3
Median raphe nucleus
nTPM: 446.6
2220 Male, age 76, midline 446.6
Pedunculopontine tegmental nucleus
nTPM: 419.1
2334 Male, age 80, both hemispheres 435.7
1921 Female, age 85, both hemispheres 421.0
2338 Male, age 61, both hemispheres 400.6
Periaquaductal grey, anterior
nTPM: 421.8
1795 Male, age 51, unknown 431.7
1947 Male, age 18, unknown 427.4
2502 Female, age 75, unknown 406.2
Periaquaductal grey, dorsal
nTPM: 406.8
2850 Male, age 76, both hemispheres 431.7
1840 Male, age 53, unknown 407.1
1831 Male, age 72, unknown 402.3
2464 Female, age 72, unknown 386.3
Periaquaductal grey, lateral
nTPM: 404.6
2272 Male, age 74, both hemispheres 411.9
2053 Male, age 18, unknown 401.8
2140 Male, age 76, both hemispheres 400.1
Pretectal area
nTPM: 421.7
1816 Male, age 51, unknown 448.5
1817 Female, age 42, unknown 448.3
1944 Female, age 72, unknown 442.2
2007 Male, age 72, unknown 437.3
2667 Female, age 75, unknown 431.2
1815 Male, age 53, unknown 426.6
2224 Female, age 72, unknown 416.7
2825 Male, age 18, unknown 407.9
2273 Male, age 74, both hemispheres 407.5
2316 Male, age 76, right hemisphere 386.9
2407 Male, age 75, both hemispheres 385.1
Red nucleus
nTPM: 418.1
1821 Female, age 72, unknown 448.5
2725 Female, age 75, unknown 446.2
2503 Female, age 72, unknown 424.0
1954 Female, age 42, unknown 417.1
2769 Male, age 72, unknown 415.9
1904 Male, age 53, unknown 415.5
2227 Male, age 72, unknown 414.4
2785 Male, age 18, unknown 410.8
2588 Male, age 74, left hemisphere 407.7
1865 Male, age 51, unknown 407.6
2584 Male, age 75, left hemisphere 406.5
2823 Male, age 76, right hemisphere 402.5
Substantia nigra
nTPM: 448.3
1916 Female, age 42, unknown 510.8
1851 Male, age 51, unknown 477.8
2699 Male, age 18, unknown 466.2
2665 Male, age 74, both hemispheres 456.1
1889 Female, age 72, unknown 442.8
1941 Male, age 53, unknown 431.7
2409 Female, age 72, unknown 428.0
2583 Male, age 75, right hemisphere 424.7
2241 Male, age 72, unknown 422.2
2590 Female, age 75, unknown 422.2
Superior colliculus
nTPM: 403.8
1796 Male, age 53, unknown 431.0
2261 Male, age 18, unknown 410.7
2087 Female, age 72, unknown 409.8
2587 Male, age 74, left hemisphere 406.3
2668 Female, age 75, unknown 403.4
1895 Male, age 76, right hemisphere 399.5
1839 Male, age 51, unknown 396.6
1913 Female, age 42, unknown 395.9
2664 Male, age 75, both hemispheres 395.5
1995 Male, age 72, unknown 389.2
Ventral tegmental area
nTPM: 438.7
1915 Female, age 42, unknown 467.7
2410 Female, age 72, unknown 455.7
2218 Male, age 76, both hemispheres 455.3
2223 Female, age 72, unknown 423.6
1942 Male, age 51, unknown 418.9
2021 Male, age 53, unknown 410.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 574.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 574.4
Samples: 139

Max nTPM: 1087.0
Min nTPM: 254.2
Std nTPM: 154.3
Median nTPM: 572.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1087.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 965.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 933.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 933.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 906.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 887.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 885.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 863.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 845.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 819.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 767.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 759.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 756.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 751.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 749.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 731.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 731.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 725.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 724.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 724.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 723.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 723.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 722.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 720.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 716.3
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 712.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 711.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 702.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 700.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 694.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 691.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 683.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 681.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 679.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 677.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 676.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 670.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 667.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 644.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 643.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 640.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 638.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 636.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 632.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 631.7
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 628.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 624.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 622.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 622.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 621.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 619.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 619.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 616.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 614.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 613.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 611.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 607.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 604.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 602.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 594.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 591.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 589.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 588.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 584.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 584.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 584.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 582.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 578.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 578.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 572.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 565.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 565.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 564.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 560.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 560.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 553.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 550.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 544.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 542.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 540.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 536.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 535.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 532.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 529.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 527.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 527.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 526.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 522.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 522.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 519.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 513.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 505.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 504.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 503.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 502.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 499.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 496.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 486.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 485.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 482.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 470.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 466.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 463.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 462.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 460.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 458.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 457.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 455.8
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 452.7
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 451.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 451.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 450.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 444.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 441.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 435.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 433.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 430.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 427.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 425.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 417.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 406.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 403.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 401.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 400.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 381.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 368.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 367.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 352.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 346.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 342.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 328.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 326.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 316.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 310.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 300.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 298.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 278.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 273.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 254.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 396.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 396.5
FF:10158-103A5 76 years, female 396.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 123.4
Pig sample Sample description nTPM
Midbrain
nTPM: 101.6
Samples: 4

Max nTPM: 118.0
Min nTPM: 89.8
Sample A Female 97.0
Sample B Female 89.8
Sample C Male 118.0
Sample D Male 101.5
Periaqueductal gray
nTPM: 74.2
Samples: 3

Max nTPM: 87.3
Min nTPM: 67.2
Sample B Female 68.1
Sample C Male 87.3
Sample D Male 67.2
Substantia nigra
nTPM: 104.2
Samples: 4

Max nTPM: 158.0
Min nTPM: 64.5
Sample A Female 158.0
Sample B Female 76.8
Sample C Male 117.6
Sample D Male 64.5
Superior colliculi
nTPM: 123.4
Samples: 4

Max nTPM: 161.2
Min nTPM: 97.7
Sample A Female 161.2
Sample B Female 97.7
Sample C Male 133.8
Sample D Male 100.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 623.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 623.0
Samples: 4

Max nTPM: 699.3
Min nTPM: 539.1
Sample A Male 699.3
Sample B Male 588.5
Sample C Female 539.1
Sample D Female 665.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 11.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 11.8
69734572 Antisense, RP_050503_01_B10, Mouse strain C57BL/6J (56 days, male) 11.8

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