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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:132.6 nTPM
HPA:132.6 nTPM
GTEx:120.5 nTPM
FANTOM5:144.2 Scaled Tags Per Million
Pig:124.2 nTPM
Mouse:134.5 nTPM
Allen mouse:2.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 132.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 126.6
2019 Male, age 18, unknown 139.1
2828 Female, age 72, unknown 137.7
2666 Male, age 74, left hemisphere 132.1
2586 Male, age 75, left hemisphere 128.9
1827 Male, age 72, unknown 128.7
2411 Female, age 72, unknown 123.6
1833 Male, age 53, unknown 123.0
1870 Female, age 42, unknown 122.0
1830 Male, age 51, unknown 120.5
2219 Male, age 76, both hemispheres 110.7
Dorsal raphe nucleus
nTPM: 132.6
2298 Female, age 72, unknown 138.9
1828 Male, age 53, unknown 134.4
2047 Male, age 72, unknown 132.6
2016 Female, age 72, unknown 130.9
2750 Male, age 76, both hemispheres 126.2
Inferior colliculus
nTPM: 130.6
2097 Female, age 72, unknown 142.8
1890 Male, age 53, unknown 128.6
1848 Female, age 42, unknown 126.3
2849 Male, age 72, unknown 124.8
Median raphe nucleus
nTPM: 124.7
2220 Male, age 76, midline 124.7
Pedunculopontine tegmental nucleus
nTPM: 122.9
2334 Male, age 80, both hemispheres 129.7
1921 Female, age 85, both hemispheres 123.0
2338 Male, age 61, both hemispheres 116.0
Periaquaductal grey, anterior
nTPM: 131.1
2502 Female, age 75, unknown 136.0
1795 Male, age 51, unknown 131.7
1947 Male, age 18, unknown 125.5
Periaquaductal grey, dorsal
nTPM: 125.7
2850 Male, age 76, both hemispheres 132.8
1840 Male, age 53, unknown 126.9
2464 Female, age 72, unknown 124.5
1831 Male, age 72, unknown 118.6
Periaquaductal grey, lateral
nTPM: 127.4
2140 Male, age 76, both hemispheres 136.7
2272 Male, age 74, both hemispheres 123.4
2053 Male, age 18, unknown 122.2
Pretectal area
nTPM: 130.8
1817 Female, age 42, unknown 144.3
2007 Male, age 72, unknown 140.3
1816 Male, age 51, unknown 134.3
1944 Female, age 72, unknown 133.7
1815 Male, age 53, unknown 132.4
2273 Male, age 74, both hemispheres 130.1
2667 Female, age 75, unknown 128.8
2316 Male, age 76, right hemisphere 128.3
2224 Female, age 72, unknown 125.6
2825 Male, age 18, unknown 122.1
2407 Male, age 75, both hemispheres 118.9
Red nucleus
nTPM: 131.1
1954 Female, age 42, unknown 140.5
1821 Female, age 72, unknown 139.6
2785 Male, age 18, unknown 137.9
2769 Male, age 72, unknown 134.3
2227 Male, age 72, unknown 132.9
2503 Female, age 72, unknown 132.3
1904 Male, age 53, unknown 131.1
2725 Female, age 75, unknown 128.8
2588 Male, age 74, left hemisphere 127.8
1865 Male, age 51, unknown 125.6
2823 Male, age 76, right hemisphere 125.2
2584 Male, age 75, left hemisphere 116.7
Substantia nigra
nTPM: 127.3
1916 Female, age 42, unknown 144.1
1889 Female, age 72, unknown 134.8
1851 Male, age 51, unknown 133.0
2665 Male, age 74, both hemispheres 131.8
2699 Male, age 18, unknown 127.1
1941 Male, age 53, unknown 122.8
2583 Male, age 75, right hemisphere 121.8
2590 Female, age 75, unknown 121.0
2241 Male, age 72, unknown 120.6
2409 Female, age 72, unknown 115.6
Superior colliculus
nTPM: 126.0
2087 Female, age 72, unknown 131.3
2668 Female, age 75, unknown 130.3
1995 Male, age 72, unknown 128.3
1796 Male, age 53, unknown 128.1
2587 Male, age 74, left hemisphere 126.3
1839 Male, age 51, unknown 126.2
2261 Male, age 18, unknown 125.6
2664 Male, age 75, both hemispheres 122.2
1895 Male, age 76, right hemisphere 121.1
1913 Female, age 42, unknown 120.3
Ventral tegmental area
nTPM: 127.3
1915 Female, age 42, unknown 132.1
2410 Female, age 72, unknown 131.8
2021 Male, age 53, unknown 127.2
1942 Male, age 51, unknown 126.7
2218 Male, age 76, both hemispheres 124.9
2223 Female, age 72, unknown 121.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 120.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 120.5
Samples: 139

Max nTPM: 378.7
Min nTPM: 56.4
Std nTPM: 56.9
Median nTPM: 105.6
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 378.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 368.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 300.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 300.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 297.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 278.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 272.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 232.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 232.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 227.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 208.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 187.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 181.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 180.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 176.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 174.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 172.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 169.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 164.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 163.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 161.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 160.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 145.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 144.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 144.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 142.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 140.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 138.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 136.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 135.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 135.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 135.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 132.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 131.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 131.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 131.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 131.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 129.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 127.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 127.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 125.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 124.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 124.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 124.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 122.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 121.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 121.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 121.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 121.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 118.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 117.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 116.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 114.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 112.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 112.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 111.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 111.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 110.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 109.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 109.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 109.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 109.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 108.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 108.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 108.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 108.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 107.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 107.7
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 106.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 105.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 104.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 102.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 101.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 101.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 101.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 101.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 100.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 100.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 100.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 100.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 100.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 98.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 98.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 98.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 98.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 97.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 97.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 97.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 95.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 95.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 94.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 94.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 94.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 93.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 93.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 93.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 92.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 92.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 91.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 91.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 90.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 90.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 88.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 88.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 88.3
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 87.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 87.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 86.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 84.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 84.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 83.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 82.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 82.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 81.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 77.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 77.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 77.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 75.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 74.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 74.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 73.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 73.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 73.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 73.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 72.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 71.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 71.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 71.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 71.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 70.5
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 68.0
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 68.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 67.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 66.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 65.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 64.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 60.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 57.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 56.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 144.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 144.2
FF:10158-103A5 76 years, female 144.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 124.2
Pig sample Sample description nTPM
Midbrain
nTPM: 111.9
Samples: 4

Max nTPM: 123.2
Min nTPM: 94.9
Sample A Female 123.2
Sample B Female 106.8
Sample C Male 122.6
Sample D Male 94.9
Periaqueductal gray
nTPM: 101.8
Samples: 3

Max nTPM: 120.5
Min nTPM: 88.0
Sample B Female 97.0
Sample C Male 120.5
Sample D Male 88.0
Substantia nigra
nTPM: 124.2
Samples: 4

Max nTPM: 139.7
Min nTPM: 103.8
Sample A Female 135.9
Sample B Female 117.2
Sample C Male 139.7
Sample D Male 103.8
Superior colliculi
nTPM: 122.3
Samples: 4

Max nTPM: 139.9
Min nTPM: 111.1
Sample A Female 139.9
Sample B Female 118.3
Sample C Male 120.0
Sample D Male 111.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 134.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 134.4
Samples: 4

Max nTPM: 137.6
Min nTPM: 133.0
Sample A Male 133.3
Sample B Male 133.8
Sample C Female 133.0
Sample D Female 137.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.6
69873971 Antisense, RP_050512_02_D06, Mouse strain C57BL/6J (56 days, male) 2.6

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