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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:219.3 nTPM
HPA:219.3 nTPM
GTEx:151.4 nTPM
FANTOM5:489.2 Scaled Tags Per Million
Pig:125.5 nTPM
Mouse:144.0 nTPM
Allen mouse:3.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 219.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 190.8
2411 Female, age 72, unknown 208.1
1833 Male, age 53, unknown 203.6
2828 Female, age 72, unknown 202.1
1830 Male, age 51, unknown 201.3
1870 Female, age 42, unknown 198.8
1827 Male, age 72, unknown 193.6
2019 Male, age 18, unknown 188.2
2666 Male, age 74, left hemisphere 179.9
2219 Male, age 76, both hemispheres 176.4
2586 Male, age 75, left hemisphere 156.0
Dorsal raphe nucleus
nTPM: 194.2
2750 Male, age 76, both hemispheres 216.8
2016 Female, age 72, unknown 190.0
2047 Male, age 72, unknown 189.3
1828 Male, age 53, unknown 188.6
2298 Female, age 72, unknown 186.5
Inferior colliculus
nTPM: 194.8
1848 Female, age 42, unknown 198.2
2849 Male, age 72, unknown 197.2
2097 Female, age 72, unknown 192.4
1890 Male, age 53, unknown 191.3
Median raphe nucleus
nTPM: 219.3
2220 Male, age 76, midline 219.3
Pedunculopontine tegmental nucleus
nTPM: 192.3
2334 Male, age 80, both hemispheres 200.0
1921 Female, age 85, both hemispheres 198.1
2338 Male, age 61, both hemispheres 178.8
Periaquaductal grey, anterior
nTPM: 183.6
1947 Male, age 18, unknown 193.6
1795 Male, age 51, unknown 179.2
2502 Female, age 75, unknown 177.9
Periaquaductal grey, dorsal
nTPM: 202.4
2850 Male, age 76, both hemispheres 226.6
2464 Female, age 72, unknown 200.3
1831 Male, age 72, unknown 197.5
1840 Male, age 53, unknown 185.1
Periaquaductal grey, lateral
nTPM: 199.6
2140 Male, age 76, both hemispheres 214.9
2053 Male, age 18, unknown 196.3
2272 Male, age 74, both hemispheres 187.7
Pretectal area
nTPM: 193.7
2667 Female, age 75, unknown 218.7
2316 Male, age 76, right hemisphere 202.2
1815 Male, age 53, unknown 199.7
2407 Male, age 75, both hemispheres 194.4
2273 Male, age 74, both hemispheres 194.3
2825 Male, age 18, unknown 193.2
1817 Female, age 42, unknown 190.5
1944 Female, age 72, unknown 189.9
2224 Female, age 72, unknown 189.4
1816 Male, age 51, unknown 179.5
2007 Male, age 72, unknown 178.5
Red nucleus
nTPM: 206.5
2823 Male, age 76, right hemisphere 227.2
1904 Male, age 53, unknown 218.1
1954 Female, age 42, unknown 216.4
1821 Female, age 72, unknown 213.3
1865 Male, age 51, unknown 211.0
2503 Female, age 72, unknown 209.9
2725 Female, age 75, unknown 209.8
2227 Male, age 72, unknown 204.3
2769 Male, age 72, unknown 204.2
2588 Male, age 74, left hemisphere 193.6
2785 Male, age 18, unknown 188.4
2584 Male, age 75, left hemisphere 182.0
Substantia nigra
nTPM: 196.8
2699 Male, age 18, unknown 219.0
2409 Female, age 72, unknown 217.8
1851 Male, age 51, unknown 200.6
2241 Male, age 72, unknown 198.2
2590 Female, age 75, unknown 194.6
2583 Male, age 75, right hemisphere 193.6
1916 Female, age 42, unknown 193.3
1889 Female, age 72, unknown 191.7
1941 Male, age 53, unknown 188.8
2665 Male, age 74, both hemispheres 170.6
Superior colliculus
nTPM: 189.1
1913 Female, age 42, unknown 209.1
1995 Male, age 72, unknown 206.0
1895 Male, age 76, right hemisphere 200.7
2087 Female, age 72, unknown 192.9
1839 Male, age 51, unknown 190.6
2587 Male, age 74, left hemisphere 190.1
1796 Male, age 53, unknown 185.7
2261 Male, age 18, unknown 178.4
2668 Female, age 75, unknown 172.0
2664 Male, age 75, both hemispheres 165.1
Ventral tegmental area
nTPM: 196.3
2410 Female, age 72, unknown 210.4
2021 Male, age 53, unknown 199.9
2218 Male, age 76, both hemispheres 197.2
1915 Female, age 42, unknown 192.6
1942 Male, age 51, unknown 192.0
2223 Female, age 72, unknown 185.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 151.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 151.4
Samples: 139

Max nTPM: 357.9
Min nTPM: 71.2
Std nTPM: 41.6
Median nTPM: 147.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 357.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 273.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 236.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 235.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 228.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 228.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 223.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 219.5
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 218.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 214.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 213.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 211.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 209.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 209.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 207.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 204.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 200.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 196.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 196.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 194.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 193.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 189.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 188.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 187.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 185.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 183.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 179.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 179.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 178.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 178.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 176.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 176.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 176.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 173.4
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 172.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 172.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 172.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 171.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 171.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 171.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 171.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 169.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 169.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 169.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 167.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 167.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 166.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 166.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 165.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 164.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 164.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 164.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 163.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 163.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 160.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 156.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 152.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 152.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 152.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 151.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 150.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 149.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 149.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 149.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 149.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 148.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 148.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 148.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 148.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 147.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 145.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 144.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 143.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 143.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 142.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 141.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 140.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 140.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 139.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 138.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 138.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 137.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 134.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 133.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 133.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 131.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 131.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 130.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 130.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 128.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 128.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 128.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 128.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 128.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 128.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 127.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 127.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 127.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 126.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 126.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 125.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 125.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 124.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 124.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 124.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 123.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 121.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 120.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 119.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 118.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 117.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 116.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 116.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 114.6
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 114.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 114.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 114.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 114.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 114.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 112.3
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 111.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 111.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 110.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 108.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 108.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 105.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 103.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 101.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 97.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 97.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 96.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 96.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 93.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 92.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 88.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 86.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 80.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 74.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 71.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 489.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 489.2
FF:10158-103A5 76 years, female 489.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 125.5
Pig sample Sample description nTPM
Midbrain
nTPM: 123.2
Samples: 4

Max nTPM: 155.4
Min nTPM: 104.7
Sample A Female 155.4
Sample B Female 125.1
Sample C Male 104.7
Sample D Male 107.6
Periaqueductal gray
nTPM: 101.7
Samples: 3

Max nTPM: 111.8
Min nTPM: 96.3
Sample B Female 111.8
Sample C Male 96.9
Sample D Male 96.3
Substantia nigra
nTPM: 125.5
Samples: 4

Max nTPM: 133.1
Min nTPM: 113.2
Sample A Female 132.4
Sample B Female 113.2
Sample C Male 133.1
Sample D Male 123.3
Superior colliculi
nTPM: 115.6
Samples: 4

Max nTPM: 120.1
Min nTPM: 110.7
Sample A Female 112.8
Sample B Female 118.9
Sample C Male 120.1
Sample D Male 110.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 144.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 144.0
Samples: 4

Max nTPM: 153.6
Min nTPM: 137.4
Sample A Male 137.4
Sample B Male 140.5
Sample C Female 153.6
Sample D Female 144.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.1
67978473 Antisense, RP_040923_01_B10, Mouse strain C57BL/6J (56 days, male) 6.2
71991953 Antisense, RP_051012_03_G11, Mouse strain C57BL/6J (56 days, male) 0.0

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