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BRAIN PONS AND MEDULLA Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
PONS AND MEDULLA - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:93.8 nTPM
HPA:93.8 nTPM
FANTOM5:122.0 Scaled Tags Per Million
Pig:107.7 nTPM
Mouse:30.0 nTPM
Allen mouse:1.0 Expression energy

PONS AND MEDULLA - HPA Brain RNA-seq
Max nTPM 93.8
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 44.1
2090 Male, age 80, both hemispheres 48.3
1984 Male, age 76, both hemispheres 48.0
2301 Female, age 85, both hemispheres 46.4
2188 Female, age 91, both hemispheres 33.8
Area postrema
nTPM: 69.3
2306 Male, age 80, both hemispheres 76.5
2799 Male, age 61, both hemispheres 73.0
2054 Male, age 76, both hemispheres 58.3
Cuneate nuclei
nTPM: 48.3
2131 Male, age 76, both hemispheres 55.1
2381 Male, age 80, both hemispheres 46.1
2376 Male, age 61, both hemispheres 43.8
Dorsal cochlear nucleus
nTPM: 52.5
2378 Male, age 80, both hemispheres 60.8
2802 Male, age 74, right hemisphere 60.4
2058 Male, age 76, both hemispheres 50.2
2370 Male, age 61, both hemispheres 49.9
2187 Female, age 91, both hemispheres 41.1
Dorsal medullary reticular nucleus
nTPM: 52.3
2373 Male, age 61, both hemispheres 60.7
2040 Female, age 85, both hemispheres 49.3
2088 Male, age 76, both hemispheres 46.8
Dorsal motor vagal complex
nTPM: 66.5
2643 Male, age 74, both hemispheres 79.8
2813 Female, age 72, unknown 74.1
2844 Male, age 55, unknown 71.8
2000 Male, age 74, unknown 69.2
2797 Male, age 61, both hemispheres 69.0
2185 Male, age 76, both hemispheres 68.3
2133 Female, age 91, both hemispheres 55.7
2807 Female, age 85, both hemispheres 44.0
Dorsal tegmental nucleus
nTPM: 52.1
2083 Male, age 80, both hemispheres 63.5
1936 Male, age 76, left hemisphere 56.3
2326 Male, age 74, both hemispheres 49.1
2358 Male, age 61, both hemispheres 39.5
Dorsolateral tegmental area
nTPM: 47.0
2654 Male, age 80, both hemispheres 61.1
2141 Male, age 76, both hemispheres 57.0
2751 Female, age 85, both hemispheres 39.7
2360 Male, age 74, both hemispheres 39.2
2337 Male, age 61, both hemispheres 38.1
Gigantocellular reticular nuclei, medullary
nTPM: 48.2
2314 Male, age 61, both hemispheres 78.9
2462 Male, age 74, both hemispheres 47.6
2022 Male, age 76, right hemisphere 46.3
1876 Female, age 85, both hemispheres 45.4
2387 Female, age 91, both hemispheres 38.5
2310 Male, age 80, both hemispheres 32.9
Gigantocellular reticular nuclei, pars
nTPM: 54.4
2336 Male, age 61, both hemispheres 69.9
2084 Female, age 85, both hemispheres 63.7
2330 Male, age 80, both hemispheres 52.0
2706 Male, age 80, both hemispheres 49.6
2168 Male, age 76, both hemispheres 36.6
Inferior olive
nTPM: 93.8
2628 Female, age 91, both hemispheres 106.4
2563 Male, age 74, both hemispheres 104.2
2085 Female, age 85, both hemispheres 100.6
2178 Male, age 61, both hemispheres 81.1
2379 Male, age 80, both hemispheres 76.6
Kolliker-Fuse nucleus
nTPM: 51.3
2315 Male, age 76, right hemisphere 76.9
2163 Male, age 80, both hemispheres 40.8
2793 Female, age 91, left hemisphere 36.2
Lateral lemniscal nuclei
nTPM: 32.1
2169 Male, age 76, both hemispheres 36.0
2746 Female, age 85, left hemisphere 34.2
2453 Male, age 74, right hemisphere 31.5
2320 Female, age 91, left hemisphere 30.9
2036 Male, age 80, both hemispheres 27.8
Lateral medullary reticular nucleus
nTPM: 67.4
2804 Female, age 91, both hemispheres 87.0
2374 Male, age 61, both hemispheres 86.3
2852 Male, age 80, both hemispheres 67.7
2190 Female, age 85, both hemispheres 58.5
2305 Male, age 74, both hemispheres 54.7
2044 Male, age 76, both hemispheres 50.0
Lateral parabrachial nucleus
nTPM: 45.4
2139 Female, age 85, right hemisphere 60.1
2792 Male, age 76, both hemispheres 49.1
2013 Male, age 80, both hemispheres 41.4
2790 Male, age 61, both hemispheres 31.0
Lateral vestibular nucleus
nTPM: 54.5
2311 Male, age 80, both hemispheres 63.1
2184 Male, age 76, both hemispheres 45.9
Locus coeruleus
nTPM: 53.6
2123 Female, age 91, both hemispheres 62.7
1980 Male, age 76, both hemispheres 58.5
2317 Female, age 72, unknown 55.4
2014 Male, age 55, unknown 53.5
2720 Male, age 74, both hemispheres 51.2
2162 Male, age 80, both hemispheres 49.1
2788 Male, age 74, unknown 45.0
Medial olivary nucleus
nTPM: 71.5
2138 Female, age 91, both hemispheres 94.8
1943 Male, age 61, both hemispheres 70.1
2851 Male, age 80, both hemispheres 68.6
1962 Male, age 76, both hemispheres 52.3
Medial parabrachial nucleus
nTPM: 40.1
2786 Male, age 76, both hemispheres 53.4
2156 Male, age 61, both hemispheres 41.3
2170 Female, age 91, both hemispheres 37.2
2463 Female, age 85, right hemisphere 34.3
2854 Male, age 80, both hemispheres 34.2
Medial periolivary nuclei
nTPM: 33.8
2791 Male, age 74, right hemisphere 42.4
2063 Male, age 76, both hemispheres 36.0
2458 Female, age 91, both hemispheres 31.6
2171 Female, age 85, both hemispheres 30.8
2081 Male, age 80, both hemispheres 28.1
Medial vestibular nucleus
nTPM: 55.3
2624 Male, age 61, both hemispheres 69.9
2801 Male, age 74, both hemispheres 59.3
2093 Male, age 80, both hemispheres 56.6
2134 Male, age 76, both hemispheres 54.7
2803 Female, age 91, both hemispheres 47.0
2743 Female, age 85, both hemispheres 43.9
Motor facial nucleus
nTPM: 40.0
2126 Male, age 61, both hemispheres 49.0
2795 Female, age 91, both hemispheres 43.7
2365 Male, age 74, right hemisphere 43.0
2062 Male, age 76, both hemispheres 38.5
2697 Female, age 85, both hemispheres 36.0
2327 Male, age 80, both hemispheres 29.7
Motor hypoglossal nucleus
nTPM: 54.0
2277 Male, age 76, both hemispheres 63.9
2125 Female, age 91, both hemispheres 55.1
2461 Male, age 61, both hemispheres 55.0
2182 Male, age 80, both hemispheres 50.3
2132 Female, age 85, both hemispheres 45.9
Motor trigeminal nucleus
nTPM: 41.0
2309 Male, age 76, both hemispheres 52.6
2335 Male, age 61, both hemispheres 48.9
2321 Female, age 91, both hemispheres 39.5
2560 Male, age 74, both hemispheres 36.6
2079 Male, age 80, both hemispheres 27.5
Nuclei of the trapezoid body
nTPM: 37.5
1983 Male, age 76, both hemispheres 52.9
2368 Female, age 91, both hemispheres 36.0
2159 Male, age 61, both hemispheres 35.4
2166 Male, age 80, both hemispheres 32.5
2735 Female, age 85, both hemispheres 30.8
Nucleus ambiguus
nTPM: 55.1
2071 Male, age 76, both hemispheres 71.0
2096 Female, age 85, both hemispheres 39.1
Nucleus cuneatus
nTPM: 62.1
2564 Male, age 74, both hemispheres 71.8
2805 Female, age 91, both hemispheres 67.1
2100 Male, age 76, both hemispheres 63.9
2562 Male, age 61, both hemispheres 63.1
2808 Female, age 85, both hemispheres 58.9
2380 Male, age 80, both hemispheres 47.7
Nucleus gracilis
nTPM: 66.9
2627 Male, age 74, both hemispheres 92.1
2299 Female, age 85, both hemispheres 55.7
2382 Male, age 80, both hemispheres 53.0
Nucleus raphe magnus
nTPM: 36.6
2051 Male, age 76, both hemispheres 48.2
2455 Male, age 74, both hemispheres 42.8
2328 Male, age 80, both hemispheres 41.5
2160 Male, age 61, both hemispheres 33.4
2172 Female, age 85, both hemispheres 27.5
2459 Female, age 91, both hemispheres 26.2
Nucleus raphe obscurus
nTPM: 59.3
2142 Male, age 76, midline 72.9
2800 Male, age 61, midline 52.8
2845 Female, age 85, midline 52.1
Nucleus raphe pallidus
nTPM: 58.6
1924 Male, age 61, midline 62.3
2183 Male, age 80, midline 60.3
2145 Male, age 76, midline 53.3
Nucleus tractus solitarii
nTPM: 48.6
2656 Male, age 76, both hemispheres 51.2
2144 Female, age 91, right hemisphere 50.2
2191 Female, age 85, both hemispheres 47.8
2307 Male, age 80, both hemispheres 45.0
Paramedian reticular nucleus
nTPM: 46.8
2313 Male, age 61, both hemispheres 62.7
2057 Male, age 80, both hemispheres 46.1
2052 Male, age 76, both hemispheres 41.9
2050 Female, age 85, both hemispheres 36.3
Parvicellular reticular nuclei
nTPM: 43.7
2119 Male, age 80, both hemispheres 51.4
2095 Male, age 76, both hemispheres 48.4
2558 Male, age 74, both hemispheres 31.1
Parvicellular reticular nuclei, medullary
nTPM: 59.6
2181 Male, age 80, left hemisphere 65.3
2091 Female, age 85, both hemispheres 63.7
2189 Female, age 91, both hemispheres 49.6
Peritrigeminal nucleus
nTPM: 62.5
2067 Female, age 85, both hemispheres 69.7
2136 Male, age 76, both hemispheres 61.9
2179 Male, age 61, both hemispheres 55.8
Pontine nuclei
nTPM: 33.0
2115 Male, age 80, left hemisphere 42.9
1968 Male, age 76, left hemisphere 41.7
2109 Female, age 72, unknown 38.8
1863 Male, age 55, unknown 33.0
2787 Female, age 85, both hemispheres 33.0
2319 Female, age 91, both hemispheres 27.1
2727 Male, age 61, right hemisphere 24.5
2454 Male, age 74, left hemisphere 22.9
Pontine raphe nucleus
nTPM: 41.1
2853 Male, age 76, midline 57.0
2122 Female, age 85, midline 25.1
Posteroventral cochlear nucleus
nTPM: 39.5
2070 Male, age 76, both hemispheres 49.7
2341 Male, age 80, both hemispheres 39.9
2371 Male, age 61, both hemispheres 39.3
2752 Female, age 85, both hemispheres 36.2
2135 Female, age 91, both hemispheres 32.3
Prepositus hypoglossal nucleus
nTPM: 64.3
2086 Male, age 80, both hemispheres 79.9
2855 Female, age 85, right hemisphere 48.6
Principal sensory trigeminal nucleus
nTPM: 36.9
2324 Male, age 76, both hemispheres 56.4
2158 Male, age 61, both hemispheres 37.9
2367 Female, age 91, left hemisphere 28.7
2008 Male, age 80, left hemisphere 24.6
Reticular pontine nucleus, caudal
nTPM: 38.4
2092 Male, age 76, both hemispheres 56.6
2559 Male, age 74, both hemispheres 39.6
2457 Female, age 91, both hemispheres 29.2
2332 Male, age 80, right hemisphere 28.2
Reticular pontine nucleus, oral
nTPM: 37.5
1939 Male, age 80, both hemispheres 50.6
2167 Male, age 76, both hemispheres 46.2
2366 Female, age 91, both hemispheres 35.5
2012 Female, age 85, both hemispheres 35.2
2361 Male, age 74, both hemispheres 20.1
Reticulotegmental nucleus
nTPM: 44.2
2333 Male, age 80, both hemispheres 49.0
2452 Male, age 74, both hemispheres 44.4
2325 Male, age 76, both hemispheres 44.3
2322 Female, age 91, both hemispheres 39.2
Spinal trigeminal nucleus, caudal
nTPM: 56.1
2642 Male, age 74, both hemispheres 67.9
2308 Male, age 80, both hemispheres 58.8
2390 Female, age 91, both hemispheres 54.0
2312 Male, age 61, both hemispheres 53.7
2447 Male, age 76, both hemispheres 46.1
Spinal trigeminal nucleus, interpolar
nTPM: 47.7
2625 Male, age 61, both hemispheres 75.3
2033 Male, age 80, both hemispheres 48.2
2389 Female, age 91, both hemispheres 43.1
2066 Male, age 76, right hemisphere 36.7
2386 Female, age 85, both hemispheres 35.3
Spinal trigeminal nucleus, oral
nTPM: 48.1
1978 Male, age 76, both hemispheres 58.4
2737 Female, age 85, both hemispheres 44.8
2164 Male, age 80, both hemispheres 40.9
Spinal vestibular nucleus
nTPM: 53.4
2780 Male, age 80, both hemispheres 61.1
2796 Male, age 61, both hemispheres 55.5
2384 Male, age 74, both hemispheres 54.7
2748 Male, age 76, both hemispheres 50.1
2186 Female, age 91, both hemispheres 49.8
2806 Female, age 85, both hemispheres 49.2
Subcoeruleus area
nTPM: 39.3
2451 Male, age 74, both hemispheres 47.8
2323 Female, age 91, left hemisphere 40.4
1958 Male, age 80, both hemispheres 39.2
2369 Female, age 85, left hemisphere 37.0
2089 Male, age 76, left hemisphere 32.2
Superior olive
nTPM: 36.8
2364 Male, age 74, right hemisphere 43.3
2329 Male, age 80, right hemisphere 40.7
2020 Male, age 76, both hemispheres 36.8
2561 Female, age 91, both hemispheres 34.9
1875 Female, age 85, both hemispheres 28.1
Superior vestibular nucleus
nTPM: 60.6
2061 Male, age 76, both hemispheres 69.7
2015 Male, age 80, both hemispheres 61.9
2383 Male, age 74, both hemispheres 50.1
Ventral medullary reticular nucleus
nTPM: 52.5
2372 Male, age 61, both hemispheres 54.7
2060 Male, age 76, both hemispheres 50.3
Ventral periolivary nuclei
nTPM: 33.9
2023 Male, age 76, both hemispheres 42.3
2165 Male, age 80, both hemispheres 37.6
2130 Female, age 85, both hemispheres 28.8
2794 Female, age 91, left hemisphere 27.0
Ventrolateral medulla, A1-C1 cell groups
nTPM: 55.6
2180 Male, age 61, both hemispheres 65.8
2302 Female, age 91, both hemispheres 65.6
1986 Male, age 76, both hemispheres 53.1
2118 Male, age 80, both hemispheres 48.3
2741 Female, age 85, both hemispheres 45.0
Ventrolateral tegmental area, A5 NE cell group
nTPM: 36.5
1959 Male, age 76, both hemispheres 44.3
2840 Female, age 85, both hemispheres 41.4
2449 Male, age 74, both hemispheres 35.5
2161 Male, age 80, both hemispheres 32.6
2359 Male, age 61, both hemispheres 32.5
2456 Female, age 91, both hemispheres 32.4

PONS AND MEDULLA - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 122.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 122.0
FF:10182-103D2 60 years, female 135.4
FF:10165-103B3 76 years, female 108.6
Medulla oblongata
Scaled Tags Per Million: 103.6
FF:10038-101F2 18-64 years, mixed 125.4
FF:10155-103A2 76 years, female 100.2
FF:10174-103C3 60 years, female 85.3
Pons
Scaled Tags Per Million: 101.3
FF:10033-101E6 18-54 years, mixed 101.3

PONS AND MEDULLA - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 107.7
Pig sample Sample description nTPM
Medulla oblongata
nTPM: 93.7
Samples: 4

Max nTPM: 101.0
Min nTPM: 88.7
Sample A Female 89.5
Sample B Female 88.7
Sample C Male 95.4
Sample D Male 101.0
Pons
nTPM: 107.8
Samples: 4

Max nTPM: 148.0
Min nTPM: 82.5
Sample A Female 148.0
Sample B Female 82.5
Sample C Male 90.5
Sample D Male 110.0

PONS AND MEDULLA - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 30.0
Mouse sample Sample description nTPM
Pons and medulla
nTPM: 30.0
Samples: 4

Max nTPM: 31.3
Min nTPM: 27.6
Sample A Male 31.3
Sample B Male 27.6
Sample C Female 31.1
Sample D Female 30.1

PONS AND MEDULLA - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.0
Allen experiment id Experiment description Expression energy
Medulla oblongata
Expression energy: 1.0
69540411 Antisense, RP_050426_01_G02, Mouse strain C57BL/6J (56 days, male) 1.0
Pons
Expression energy: 0.7
69540411 Antisense, RP_050426_01_G02, Mouse strain C57BL/6J (56 days, male) 0.7

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