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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:761.8 nTPM
HPA:761.8 nTPM
GTEx:556.5 nTPM
FANTOM5:1496.7 Scaled Tags Per Million
Pig:656.6 nTPM
Mouse:338.5 nTPM
Allen mouse:14.8 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 761.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 619.6
2411 Female, age 72, unknown 806.3
1830 Male, age 51, unknown 731.2
1870 Female, age 42, unknown 720.3
1833 Male, age 53, unknown 701.3
2019 Male, age 18, unknown 687.5
2828 Female, age 72, unknown 616.3
2586 Male, age 75, left hemisphere 490.4
2666 Male, age 74, left hemisphere 489.5
1827 Male, age 72, unknown 489.2
2219 Male, age 76, both hemispheres 463.6
Dorsal raphe nucleus
nTPM: 483.3
2750 Male, age 76, both hemispheres 763.2
2016 Female, age 72, unknown 514.5
1828 Male, age 53, unknown 451.9
2298 Female, age 72, unknown 359.0
2047 Male, age 72, unknown 327.8
Inferior colliculus
nTPM: 444.2
1890 Male, age 53, unknown 460.3
1848 Female, age 42, unknown 457.3
2849 Male, age 72, unknown 433.8
2097 Female, age 72, unknown 425.5
Median raphe nucleus
nTPM: 386.0
2220 Male, age 76, midline 386.0
Pedunculopontine tegmental nucleus
nTPM: 511.5
2334 Male, age 80, both hemispheres 559.3
1921 Female, age 85, both hemispheres 493.5
2338 Male, age 61, both hemispheres 481.8
Periaquaductal grey, anterior
nTPM: 408.4
2502 Female, age 75, unknown 443.6
1947 Male, age 18, unknown 417.9
1795 Male, age 51, unknown 363.9
Periaquaductal grey, dorsal
nTPM: 363.8
2464 Female, age 72, unknown 511.5
1831 Male, age 72, unknown 376.6
1840 Male, age 53, unknown 290.3
2850 Male, age 76, both hemispheres 276.8
Periaquaductal grey, lateral
nTPM: 384.2
2272 Male, age 74, both hemispheres 431.7
2053 Male, age 18, unknown 425.1
2140 Male, age 76, both hemispheres 295.7
Pretectal area
nTPM: 447.9
2316 Male, age 76, right hemisphere 597.7
1815 Male, age 53, unknown 574.3
2407 Male, age 75, both hemispheres 565.0
1817 Female, age 42, unknown 460.0
2007 Male, age 72, unknown 452.3
2825 Male, age 18, unknown 451.6
2273 Male, age 74, both hemispheres 414.6
2667 Female, age 75, unknown 392.1
2224 Female, age 72, unknown 378.1
1944 Female, age 72, unknown 321.8
1816 Male, age 51, unknown 319.1
Red nucleus
nTPM: 761.8
1865 Male, age 51, unknown 881.7
1904 Male, age 53, unknown 880.1
1821 Female, age 72, unknown 840.0
2823 Male, age 76, right hemisphere 835.8
2769 Male, age 72, unknown 835.4
2227 Male, age 72, unknown 829.4
2785 Male, age 18, unknown 777.8
2503 Female, age 72, unknown 753.6
1954 Female, age 42, unknown 721.6
2588 Male, age 74, left hemisphere 672.1
2725 Female, age 75, unknown 560.0
2584 Male, age 75, left hemisphere 554.4
Substantia nigra
nTPM: 479.8
1851 Male, age 51, unknown 579.3
2590 Female, age 75, unknown 570.5
2583 Male, age 75, right hemisphere 566.1
2409 Female, age 72, unknown 545.1
1889 Female, age 72, unknown 497.6
2699 Male, age 18, unknown 460.4
2241 Male, age 72, unknown 421.8
1941 Male, age 53, unknown 404.6
1916 Female, age 42, unknown 391.0
2665 Male, age 74, both hemispheres 361.6
Superior colliculus
nTPM: 555.7
1995 Male, age 72, unknown 812.7
1913 Female, age 42, unknown 749.4
1895 Male, age 76, right hemisphere 642.6
2668 Female, age 75, unknown 585.7
1839 Male, age 51, unknown 554.5
2587 Male, age 74, left hemisphere 550.8
1796 Male, age 53, unknown 474.1
2664 Male, age 75, both hemispheres 419.1
2087 Female, age 72, unknown 384.8
2261 Male, age 18, unknown 383.4
Ventral tegmental area
nTPM: 530.8
2223 Female, age 72, unknown 645.8
2410 Female, age 72, unknown 645.7
1942 Male, age 51, unknown 486.8
1915 Female, age 42, unknown 483.7
2021 Male, age 53, unknown 478.8
2218 Male, age 76, both hemispheres 444.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 556.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 556.5
Samples: 139

Max nTPM: 2285.5
Min nTPM: 156.9
Std nTPM: 342.4
Median nTPM: 459.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 2285.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 2142.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 1731.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1463.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1207.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 1205.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 1200.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1185.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1122.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1110.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1108.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1050.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1007.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 1001.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 991.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 986.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 957.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 937.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 876.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 822.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 801.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 788.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 787.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 772.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 743.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 733.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 730.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 717.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 714.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 707.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 706.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 702.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 696.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 692.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 683.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 642.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 639.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 634.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 629.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 607.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 596.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 592.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 590.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 590.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 590.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 585.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 585.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 583.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 580.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 575.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 560.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 544.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 522.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 512.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 510.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 509.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 505.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 505.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 499.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 498.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 496.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 490.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 481.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 479.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 475.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 470.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 469.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 466.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 465.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 459.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 459.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 457.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 453.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 453.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 449.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 448.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 441.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 440.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 438.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 438.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 435.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 432.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 429.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 425.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 424.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 423.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 409.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 409.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 401.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 400.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 398.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 393.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 387.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 384.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 382.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 381.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 379.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 375.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 374.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 363.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 359.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 336.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 332.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 326.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 324.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 317.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 313.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 311.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 308.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 307.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 305.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 304.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 303.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 302.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 298.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 290.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 290.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 290.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 289.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 288.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 277.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 274.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 273.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 271.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 263.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 260.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 260.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 257.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 248.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 224.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 217.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 209.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 207.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 205.1
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 202.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 194.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 171.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 170.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 156.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 1496.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1496.7
FF:10158-103A5 76 years, female 1496.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 656.6
Pig sample Sample description nTPM
Midbrain
nTPM: 656.6
Samples: 4

Max nTPM: 1455.6
Min nTPM: 270.2
Sample A Female 1455.6
Sample B Female 595.5
Sample C Male 270.2
Sample D Male 305.2
Periaqueductal gray
nTPM: 383.7
Samples: 3

Max nTPM: 476.6
Min nTPM: 276.0
Sample B Female 476.6
Sample C Male 276.0
Sample D Male 398.6
Substantia nigra
nTPM: 583.3
Samples: 4

Max nTPM: 949.3
Min nTPM: 341.5
Sample A Female 610.7
Sample B Female 341.5
Sample C Male 431.7
Sample D Male 949.3
Superior colliculi
nTPM: 483.2
Samples: 4

Max nTPM: 602.1
Min nTPM: 253.5
Sample A Female 602.1
Sample B Female 253.5
Sample C Male 476.9
Sample D Male 600.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 338.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 338.5
Samples: 4

Max nTPM: 362.9
Min nTPM: 297.9
Sample A Male 362.6
Sample B Male 297.9
Sample C Female 330.6
Sample D Female 362.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 14.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 14.8
77371841 Antisense, RP_070129_01_A04, Mouse strain C57BL/6J (56 days, male) 17.5
79488913 Antisense, RP_070129_01_A04, Mouse strain C57BL/6J (56 days, male) 14.8
1175 Antisense, RP_040407_02_H04, Mouse strain C57BL/6J (56 days, male) 12.2
1176 Antisense, RP_040407_02_H04, Mouse strain C57BL/6J (56 days, male) 10.4

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