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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:501.9 nTPM
HPA:501.9 nTPM
GTEx:545.9 nTPM
FANTOM5:193.7 Scaled Tags Per Million
Pig:160.2 nTPM
Mouse:1407.7 nTPM
Allen mouse:7.3 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 501.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 485.7
2019 Male, age 18, unknown 498.7
2411 Female, age 72, unknown 497.4
1827 Male, age 72, unknown 494.7
1870 Female, age 42, unknown 491.1
1833 Male, age 53, unknown 483.2
2666 Male, age 74, left hemisphere 481.2
2219 Male, age 76, both hemispheres 479.8
1830 Male, age 51, unknown 478.9
2828 Female, age 72, unknown 477.2
2586 Male, age 75, left hemisphere 475.2
Dorsal raphe nucleus
nTPM: 492.5
2298 Female, age 72, unknown 507.6
1828 Male, age 53, unknown 494.6
2047 Male, age 72, unknown 491.4
2750 Male, age 76, both hemispheres 490.1
2016 Female, age 72, unknown 478.6
Inferior colliculus
nTPM: 497.3
2097 Female, age 72, unknown 512.8
1890 Male, age 53, unknown 502.8
1848 Female, age 42, unknown 490.6
2849 Male, age 72, unknown 483.0
Median raphe nucleus
nTPM: 489.2
2220 Male, age 76, midline 489.2
Pedunculopontine tegmental nucleus
nTPM: 501.9
1921 Female, age 85, both hemispheres 510.7
2334 Male, age 80, both hemispheres 500.6
2338 Male, age 61, both hemispheres 494.5
Periaquaductal grey, anterior
nTPM: 491.2
1947 Male, age 18, unknown 501.1
1795 Male, age 51, unknown 491.4
2502 Female, age 75, unknown 481.2
Periaquaductal grey, dorsal
nTPM: 482.9
2850 Male, age 76, both hemispheres 485.8
2464 Female, age 72, unknown 483.5
1831 Male, age 72, unknown 483.1
1840 Male, age 53, unknown 479.2
Periaquaductal grey, lateral
nTPM: 483.2
2272 Male, age 74, both hemispheres 495.0
2053 Male, age 18, unknown 481.6
2140 Male, age 76, both hemispheres 473.0
Pretectal area
nTPM: 500.4
1816 Male, age 51, unknown 524.0
2007 Male, age 72, unknown 518.8
1817 Female, age 42, unknown 517.2
1944 Female, age 72, unknown 510.9
1815 Male, age 53, unknown 505.3
2224 Female, age 72, unknown 501.9
2667 Female, age 75, unknown 501.7
2273 Male, age 74, both hemispheres 489.5
2316 Male, age 76, right hemisphere 480.6
2825 Male, age 18, unknown 480.5
2407 Male, age 75, both hemispheres 473.7
Red nucleus
nTPM: 493.2
1821 Female, age 72, unknown 514.4
2725 Female, age 75, unknown 512.9
2785 Male, age 18, unknown 496.8
2584 Male, age 75, left hemisphere 494.5
1865 Male, age 51, unknown 489.6
2503 Female, age 72, unknown 489.6
2823 Male, age 76, right hemisphere 489.5
1954 Female, age 42, unknown 489.2
2769 Male, age 72, unknown 486.6
2227 Male, age 72, unknown 485.5
2588 Male, age 74, left hemisphere 485.3
1904 Male, age 53, unknown 484.2
Substantia nigra
nTPM: 497.0
1889 Female, age 72, unknown 523.9
2241 Male, age 72, unknown 508.7
1916 Female, age 42, unknown 505.0
1851 Male, age 51, unknown 504.2
1941 Male, age 53, unknown 503.4
2665 Male, age 74, both hemispheres 489.7
2409 Female, age 72, unknown 488.1
2590 Female, age 75, unknown 484.5
2699 Male, age 18, unknown 484.0
2583 Male, age 75, right hemisphere 478.1
Superior colliculus
nTPM: 488.7
1796 Male, age 53, unknown 497.7
2087 Female, age 72, unknown 496.3
2261 Male, age 18, unknown 492.5
1895 Male, age 76, right hemisphere 491.2
2587 Male, age 74, left hemisphere 491.2
2668 Female, age 75, unknown 489.9
1913 Female, age 42, unknown 489.1
1839 Male, age 51, unknown 481.4
1995 Male, age 72, unknown 479.6
2664 Male, age 75, both hemispheres 478.1
Ventral tegmental area
nTPM: 493.7
2410 Female, age 72, unknown 510.2
2223 Female, age 72, unknown 499.0
1915 Female, age 42, unknown 497.6
2218 Male, age 76, both hemispheres 492.8
1942 Male, age 51, unknown 483.6
2021 Male, age 53, unknown 479.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 545.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 545.9
Samples: 139

Max nTPM: 1287.4
Min nTPM: 284.4
Std nTPM: 148.2
Median nTPM: 519.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1287.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1172.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 897.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 871.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 868.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 826.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 815.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 811.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 784.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 757.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 753.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 739.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 734.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 728.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 717.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 713.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 710.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 697.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 696.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 689.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 685.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 671.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 664.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 649.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 649.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 638.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 635.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 629.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 622.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 621.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 616.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 612.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 602.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 599.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 596.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 594.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 594.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 593.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 588.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 588.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 587.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 587.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 586.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 586.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 583.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 580.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 577.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 575.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 573.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 571.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 567.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 566.8
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 566.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 564.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 561.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 558.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 558.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 556.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 548.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 547.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 543.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 541.8
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 540.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 537.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 533.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 528.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 527.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 524.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 521.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 519.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 518.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 517.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 515.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 514.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 513.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 511.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 511.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 508.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 508.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 508.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 507.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 502.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 499.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 497.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 496.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 495.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 492.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 491.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 490.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 488.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 488.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 487.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 486.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 486.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 484.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 483.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 482.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 476.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 475.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 472.3
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 460.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 443.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 442.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 442.6
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 440.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 439.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 439.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 437.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 436.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 434.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 433.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 433.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 432.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 430.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 428.8
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 426.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 422.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 412.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 406.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 402.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 401.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 400.7
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 392.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 391.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 390.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 387.0
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 381.3
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 380.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 379.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 372.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 364.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 357.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 351.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 346.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 330.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 321.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 319.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 311.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 284.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 193.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 193.7
FF:10158-103A5 76 years, female 193.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 160.2
Pig sample Sample description nTPM
Midbrain
nTPM: 136.0
Samples: 4

Max nTPM: 149.9
Min nTPM: 122.3
Sample A Female 122.3
Sample B Female 130.0
Sample C Male 141.7
Sample D Male 149.9
Periaqueductal gray
nTPM: 100.9
Samples: 3

Max nTPM: 114.7
Min nTPM: 87.6
Sample B Female 100.3
Sample C Male 114.7
Sample D Male 87.6
Substantia nigra
nTPM: 132.7
Samples: 4

Max nTPM: 206.6
Min nTPM: 81.4
Sample A Female 206.6
Sample B Female 123.9
Sample C Male 118.9
Sample D Male 81.4
Superior colliculi
nTPM: 160.2
Samples: 4

Max nTPM: 226.2
Min nTPM: 120.2
Sample A Female 226.2
Sample B Female 125.1
Sample C Male 169.2
Sample D Male 120.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1407.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 1407.7
Samples: 4

Max nTPM: 1522.0
Min nTPM: 1292.9
Sample A Male 1493.6
Sample B Male 1322.2
Sample C Female 1292.9
Sample D Female 1522.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 7.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.3
67862431 Antisense, RP_041018_01_C03, Mouse strain C57BL/6J (56 days, male) 7.3
68203444 Antisense, RP_041018_01_C03, Mouse strain C57BL/6J (56 days, male) 5.1

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