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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:82.1 nTPM
HPA:82.1 nTPM
GTEx:62.1 nTPM
FANTOM5:81.7 Scaled Tags Per Million
Pig:54.8 nTPM
Mouse:55.5 nTPM
Allen mouse:2.3 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 82.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 78.2
1827 Male, age 72, unknown 82.2
2219 Male, age 76, both hemispheres 80.3
2666 Male, age 74, left hemisphere 79.4
1870 Female, age 42, unknown 79.2
2411 Female, age 72, unknown 79.2
1830 Male, age 51, unknown 78.4
1833 Male, age 53, unknown 78.4
2828 Female, age 72, unknown 78.3
2019 Male, age 18, unknown 74.2
2586 Male, age 75, left hemisphere 72.9
Dorsal raphe nucleus
nTPM: 79.9
2298 Female, age 72, unknown 85.3
2047 Male, age 72, unknown 84.3
2750 Male, age 76, both hemispheres 78.7
2016 Female, age 72, unknown 75.9
1828 Male, age 53, unknown 75.2
Inferior colliculus
nTPM: 80.0
1848 Female, age 42, unknown 82.6
2097 Female, age 72, unknown 80.1
2849 Male, age 72, unknown 79.9
1890 Male, age 53, unknown 77.4
Median raphe nucleus
nTPM: 82.1
2220 Male, age 76, midline 82.1
Pedunculopontine tegmental nucleus
nTPM: 78.8
2334 Male, age 80, both hemispheres 82.7
1921 Female, age 85, both hemispheres 79.7
2338 Male, age 61, both hemispheres 74.1
Periaquaductal grey, anterior
nTPM: 79.7
1947 Male, age 18, unknown 83.6
2502 Female, age 75, unknown 79.6
1795 Male, age 51, unknown 75.9
Periaquaductal grey, dorsal
nTPM: 78.7
1840 Male, age 53, unknown 80.9
2850 Male, age 76, both hemispheres 80.1
2464 Female, age 72, unknown 77.2
1831 Male, age 72, unknown 76.7
Periaquaductal grey, lateral
nTPM: 80.6
2272 Male, age 74, both hemispheres 81.3
2140 Male, age 76, both hemispheres 80.3
2053 Male, age 18, unknown 80.1
Pretectal area
nTPM: 80.5
1816 Male, age 51, unknown 86.5
2273 Male, age 74, both hemispheres 82.5
2407 Male, age 75, both hemispheres 81.7
1815 Male, age 53, unknown 81.0
1944 Female, age 72, unknown 80.9
2007 Male, age 72, unknown 80.8
2825 Male, age 18, unknown 79.9
2316 Male, age 76, right hemisphere 79.5
1817 Female, age 42, unknown 77.5
2224 Female, age 72, unknown 77.5
2667 Female, age 75, unknown 77.5
Red nucleus
nTPM: 77.2
1954 Female, age 42, unknown 79.9
1865 Male, age 51, unknown 79.2
1904 Male, age 53, unknown 79.1
2227 Male, age 72, unknown 77.8
2725 Female, age 75, unknown 77.5
2769 Male, age 72, unknown 77.4
2785 Male, age 18, unknown 77.3
2823 Male, age 76, right hemisphere 77.0
2503 Female, age 72, unknown 76.8
1821 Female, age 72, unknown 76.5
2588 Male, age 74, left hemisphere 74.4
2584 Male, age 75, left hemisphere 73.1
Substantia nigra
nTPM: 79.8
1916 Female, age 42, unknown 83.7
1889 Female, age 72, unknown 83.1
2665 Male, age 74, both hemispheres 82.9
2590 Female, age 75, unknown 81.0
1941 Male, age 53, unknown 80.9
1851 Male, age 51, unknown 79.5
2409 Female, age 72, unknown 78.6
2699 Male, age 18, unknown 78.2
2583 Male, age 75, right hemisphere 76.6
2241 Male, age 72, unknown 73.4
Superior colliculus
nTPM: 79.5
1895 Male, age 76, right hemisphere 83.3
2261 Male, age 18, unknown 82.3
1796 Male, age 53, unknown 82.2
2668 Female, age 75, unknown 80.7
2087 Female, age 72, unknown 78.9
1839 Male, age 51, unknown 78.7
1995 Male, age 72, unknown 78.7
2587 Male, age 74, left hemisphere 78.0
1913 Female, age 42, unknown 77.1
2664 Male, age 75, both hemispheres 75.5
Ventral tegmental area
nTPM: 78.8
2410 Female, age 72, unknown 83.1
2223 Female, age 72, unknown 79.7
2218 Male, age 76, both hemispheres 79.0
1915 Female, age 42, unknown 78.1
2021 Male, age 53, unknown 77.2
1942 Male, age 51, unknown 75.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 62.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 62.1
Samples: 139

Max nTPM: 125.3
Min nTPM: 36.9
Std nTPM: 13.9
Median nTPM: 61.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 125.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 114.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 106.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 98.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 94.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 92.0
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 86.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 84.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 78.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 77.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 77.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 77.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 76.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 76.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 76.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 76.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 75.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 75.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 75.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 75.0
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 72.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 72.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 72.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 71.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 70.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 70.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 70.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 70.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 70.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 69.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 69.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 69.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 69.5
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 69.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 68.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 68.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 67.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 67.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 67.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 66.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 66.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 66.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 66.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 66.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 66.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 66.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 66.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 66.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 65.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 65.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 65.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 65.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 64.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 64.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 64.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 64.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 64.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 63.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 63.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 63.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 63.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 62.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 62.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 62.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 62.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 62.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 61.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 61.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 61.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 61.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 61.7
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 61.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 61.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 61.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 61.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 61.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 61.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 61.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 60.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 59.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 59.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 59.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 59.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 59.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 58.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 58.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 58.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 57.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 57.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 57.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 56.9
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 56.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 56.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 56.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 55.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 55.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 55.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 55.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 55.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 55.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 55.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 54.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 52.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 52.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 52.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 52.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 52.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 52.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 52.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 51.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 50.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 50.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 49.9
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 49.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 48.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 48.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 48.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 48.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 47.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 47.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 46.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 46.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 46.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 46.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 46.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 45.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 45.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 44.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 44.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 44.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 43.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 43.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 43.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 41.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 41.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 40.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 38.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 37.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 36.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 81.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 81.7
FF:10158-103A5 76 years, female 81.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 54.8
Pig sample Sample description nTPM
Midbrain
nTPM: 51.0
Samples: 4

Max nTPM: 60.3
Min nTPM: 39.7
Sample A Female 60.3
Sample B Female 39.7
Sample C Male 58.7
Sample D Male 45.4
Periaqueductal gray
nTPM: 42.4
Samples: 3

Max nTPM: 47.8
Min nTPM: 38.2
Sample B Female 41.3
Sample C Male 47.8
Sample D Male 38.2
Substantia nigra
nTPM: 47.4
Samples: 4

Max nTPM: 52.8
Min nTPM: 41.4
Sample A Female 52.8
Sample B Female 46.0
Sample C Male 49.2
Sample D Male 41.4
Superior colliculi
nTPM: 54.8
Samples: 4

Max nTPM: 57.3
Min nTPM: 51.0
Sample A Female 56.3
Sample B Female 57.3
Sample C Male 54.6
Sample D Male 51.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 55.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 55.5
Samples: 4

Max nTPM: 59.3
Min nTPM: 48.4
Sample A Male 48.4
Sample B Male 59.3
Sample C Female 58.6
Sample D Female 55.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.3
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.3
68667270 Antisense, RP_050201_01_H11, Mouse strain C57BL/6J (56 days, male) 2.3

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