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RPL15
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:935.2 nTPM
HPA:935.2 nTPM
GTEx:767.8 nTPM
FANTOM5:63.2 Scaled Tags Per Million
Pig:258.5 nTPM
Mouse:266.6 nTPM
Allen mouse:9.6 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 935.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 894.5
2586 Male, age 75, left hemisphere 968.6
1870 Female, age 42, unknown 921.3
2411 Female, age 72, unknown 912.0
2666 Male, age 74, left hemisphere 903.5
1827 Male, age 72, unknown 901.4
2828 Female, age 72, unknown 900.8
1833 Male, age 53, unknown 872.5
1830 Male, age 51, unknown 867.2
2019 Male, age 18, unknown 851.8
2219 Male, age 76, both hemispheres 846.1
Dorsal raphe nucleus
nTPM: 903.5
2298 Female, age 72, unknown 936.6
2047 Male, age 72, unknown 904.3
2750 Male, age 76, both hemispheres 901.5
2016 Female, age 72, unknown 897.6
1828 Male, age 53, unknown 877.5
Inferior colliculus
nTPM: 900.3
2097 Female, age 72, unknown 917.4
1848 Female, age 42, unknown 903.3
1890 Male, age 53, unknown 898.1
2849 Male, age 72, unknown 882.2
Median raphe nucleus
nTPM: 879.3
2220 Male, age 76, midline 879.3
Pedunculopontine tegmental nucleus
nTPM: 883.4
2334 Male, age 80, both hemispheres 912.8
1921 Female, age 85, both hemispheres 870.3
2338 Male, age 61, both hemispheres 867.1
Periaquaductal grey, anterior
nTPM: 935.2
2502 Female, age 75, unknown 991.4
1947 Male, age 18, unknown 926.3
1795 Male, age 51, unknown 887.9
Periaquaductal grey, dorsal
nTPM: 882.8
1840 Male, age 53, unknown 933.4
2464 Female, age 72, unknown 884.9
1831 Male, age 72, unknown 877.0
2850 Male, age 76, both hemispheres 836.0
Periaquaductal grey, lateral
nTPM: 861.5
2053 Male, age 18, unknown 926.9
2272 Male, age 74, both hemispheres 835.6
2140 Male, age 76, both hemispheres 822.0
Pretectal area
nTPM: 874.4
2825 Male, age 18, unknown 890.9
2316 Male, age 76, right hemisphere 889.8
1816 Male, age 51, unknown 889.2
2224 Female, age 72, unknown 884.8
2407 Male, age 75, both hemispheres 883.8
1817 Female, age 42, unknown 882.3
1815 Male, age 53, unknown 879.1
2007 Male, age 72, unknown 876.0
1944 Female, age 72, unknown 860.4
2273 Male, age 74, both hemispheres 843.1
2667 Female, age 75, unknown 838.7
Red nucleus
nTPM: 903.4
2503 Female, age 72, unknown 941.3
1821 Female, age 72, unknown 940.2
2584 Male, age 75, left hemisphere 932.3
2769 Male, age 72, unknown 928.9
2227 Male, age 72, unknown 915.5
1865 Male, age 51, unknown 913.7
1904 Male, age 53, unknown 912.7
2588 Male, age 74, left hemisphere 886.6
1954 Female, age 42, unknown 885.2
2725 Female, age 75, unknown 880.6
2785 Male, age 18, unknown 857.4
2823 Male, age 76, right hemisphere 846.8
Substantia nigra
nTPM: 916.2
1851 Male, age 51, unknown 980.6
2665 Male, age 74, both hemispheres 939.7
2590 Female, age 75, unknown 931.0
2699 Male, age 18, unknown 922.2
1916 Female, age 42, unknown 917.2
1889 Female, age 72, unknown 900.5
2241 Male, age 72, unknown 897.5
2409 Female, age 72, unknown 893.4
2583 Male, age 75, right hemisphere 893.4
1941 Male, age 53, unknown 886.9
Superior colliculus
nTPM: 899.2
2664 Male, age 75, both hemispheres 950.1
2587 Male, age 74, left hemisphere 939.0
2261 Male, age 18, unknown 900.1
1839 Male, age 51, unknown 899.4
2668 Female, age 75, unknown 897.8
1796 Male, age 53, unknown 891.0
1913 Female, age 42, unknown 891.0
1995 Male, age 72, unknown 886.3
1895 Male, age 76, right hemisphere 873.2
2087 Female, age 72, unknown 864.1
Ventral tegmental area
nTPM: 919.2
2410 Female, age 72, unknown 947.6
2021 Male, age 53, unknown 936.9
1915 Female, age 42, unknown 929.3
2223 Female, age 72, unknown 915.1
1942 Male, age 51, unknown 902.4
2218 Male, age 76, both hemispheres 884.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 767.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 767.8
Samples: 139

Max nTPM: 1454.6
Min nTPM: 350.5
Std nTPM: 189.3
Median nTPM: 742.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1454.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1320.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1279.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1277.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 1215.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1150.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1144.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 1125.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1046.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1030.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1026.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1020.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 1001.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 994.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 993.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 993.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 985.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 982.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 978.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 975.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 966.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 966.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 961.9
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 960.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 954.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 950.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 940.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 915.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 912.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 911.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 905.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 903.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 900.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 893.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 888.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 872.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 871.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 868.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 866.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 862.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 862.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 860.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 841.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 834.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 832.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 825.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 821.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 814.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 812.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 804.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 803.5
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 802.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 802.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 800.0
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 799.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 797.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 795.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 793.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 791.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 767.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 765.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 764.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 762.6
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 758.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 750.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 750.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 747.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 746.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 744.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 742.7
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 742.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 739.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 728.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 725.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 712.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 709.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 709.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 699.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 697.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 690.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 689.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 684.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 684.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 684.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 683.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 680.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 674.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 672.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 670.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 669.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 657.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 656.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 652.8
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 652.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 646.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 645.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 643.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 643.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 640.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 639.2
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 632.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 631.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 628.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 628.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 624.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 623.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 614.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 613.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 613.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 612.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 610.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 603.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 601.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 599.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 598.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 593.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 589.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 581.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 579.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 579.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 579.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 577.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 575.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 572.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 570.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 564.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 562.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 551.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 547.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 543.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 542.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 540.8
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 532.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 509.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 508.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 498.2
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 487.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 460.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 350.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 63.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 63.2
FF:10158-103A5 76 years, female 63.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 258.5
Pig sample Sample description nTPM
Midbrain
nTPM: 243.6
Samples: 4

Max nTPM: 264.2
Min nTPM: 220.4
Sample A Female 256.9
Sample B Female 220.4
Sample C Male 264.2
Sample D Male 232.7
Periaqueductal gray
nTPM: 182.0
Samples: 3

Max nTPM: 207.7
Min nTPM: 157.0
Sample B Female 181.2
Sample C Male 207.7
Sample D Male 157.0
Substantia nigra
nTPM: 209.6
Samples: 4

Max nTPM: 263.3
Min nTPM: 169.8
Sample A Female 263.3
Sample B Female 193.7
Sample C Male 211.4
Sample D Male 169.8
Superior colliculi
nTPM: 258.5
Samples: 4

Max nTPM: 285.9
Min nTPM: 222.5
Sample A Female 285.9
Sample B Female 270.1
Sample C Male 255.6
Sample D Male 222.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 266.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 266.6
Samples: 4

Max nTPM: 291.1
Min nTPM: 231.4
Sample A Male 291.1
Sample B Male 258.4
Sample C Female 231.4
Sample D Female 285.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 9.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.6
69818299 Antisense, RP_050510_04_G12, Mouse strain C57BL/6J (56 days, male) 10.0
74882810 Antisense, RP_060315_04_H02, Mouse strain C57BL/6J (56 days, male) 9.2

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