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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:81.1 nTPM
HPA:81.1 nTPM
GTEx:70.3 nTPM
FANTOM5:64.6 Scaled Tags Per Million
Pig:110.7 nTPM
Mouse:160.2 nTPM
Allen mouse:7.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 81.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 68.4
2666 Male, age 74, left hemisphere 75.0
2586 Male, age 75, left hemisphere 72.9
1827 Male, age 72, unknown 71.6
2411 Female, age 72, unknown 70.9
2219 Male, age 76, both hemispheres 68.5
2019 Male, age 18, unknown 67.8
1870 Female, age 42, unknown 66.4
2828 Female, age 72, unknown 66.2
1833 Male, age 53, unknown 64.9
1830 Male, age 51, unknown 59.7
Dorsal raphe nucleus
nTPM: 72.0
2298 Female, age 72, unknown 79.3
2047 Male, age 72, unknown 75.0
1828 Male, age 53, unknown 72.8
2750 Male, age 76, both hemispheres 69.9
2016 Female, age 72, unknown 63.1
Inferior colliculus
nTPM: 64.2
2097 Female, age 72, unknown 68.6
1890 Male, age 53, unknown 64.1
1848 Female, age 42, unknown 63.6
2849 Male, age 72, unknown 60.3
Median raphe nucleus
nTPM: 71.8
2220 Male, age 76, midline 71.8
Pedunculopontine tegmental nucleus
nTPM: 66.3
2334 Male, age 80, both hemispheres 72.2
1921 Female, age 85, both hemispheres 68.2
2338 Male, age 61, both hemispheres 58.5
Periaquaductal grey, anterior
nTPM: 69.1
1947 Male, age 18, unknown 71.8
1795 Male, age 51, unknown 68.5
2502 Female, age 75, unknown 66.9
Periaquaductal grey, dorsal
nTPM: 62.8
1840 Male, age 53, unknown 69.1
2464 Female, age 72, unknown 63.2
1831 Male, age 72, unknown 59.7
2850 Male, age 76, both hemispheres 59.2
Periaquaductal grey, lateral
nTPM: 58.2
2053 Male, age 18, unknown 60.2
2140 Male, age 76, both hemispheres 59.5
2272 Male, age 74, both hemispheres 55.0
Pretectal area
nTPM: 67.5
1816 Male, age 51, unknown 78.0
2007 Male, age 72, unknown 74.5
1817 Female, age 42, unknown 73.9
1944 Female, age 72, unknown 72.7
2667 Female, age 75, unknown 69.8
1815 Male, age 53, unknown 67.9
2825 Male, age 18, unknown 64.7
2224 Female, age 72, unknown 63.6
2316 Male, age 76, right hemisphere 60.2
2273 Male, age 74, both hemispheres 59.9
2407 Male, age 75, both hemispheres 56.8
Red nucleus
nTPM: 63.9
1821 Female, age 72, unknown 72.2
2725 Female, age 75, unknown 67.3
2588 Male, age 74, left hemisphere 66.5
2503 Female, age 72, unknown 65.0
1954 Female, age 42, unknown 64.1
2785 Male, age 18, unknown 64.0
2769 Male, age 72, unknown 63.7
2227 Male, age 72, unknown 62.1
2584 Male, age 75, left hemisphere 61.2
1865 Male, age 51, unknown 61.1
1904 Male, age 53, unknown 60.6
2823 Male, age 76, right hemisphere 58.5
Substantia nigra
nTPM: 81.1
1916 Female, age 42, unknown 103.4
1851 Male, age 51, unknown 92.5
2241 Male, age 72, unknown 87.9
2409 Female, age 72, unknown 83.1
2665 Male, age 74, both hemispheres 80.3
1941 Male, age 53, unknown 79.4
1889 Female, age 72, unknown 75.4
2699 Male, age 18, unknown 74.5
2583 Male, age 75, right hemisphere 68.1
2590 Female, age 75, unknown 66.0
Superior colliculus
nTPM: 64.7
2668 Female, age 75, unknown 72.4
1796 Male, age 53, unknown 69.6
2087 Female, age 72, unknown 68.3
2261 Male, age 18, unknown 65.8
1895 Male, age 76, right hemisphere 65.7
2664 Male, age 75, both hemispheres 63.7
2587 Male, age 74, left hemisphere 63.3
1839 Male, age 51, unknown 62.4
1913 Female, age 42, unknown 59.2
1995 Male, age 72, unknown 56.9
Ventral tegmental area
nTPM: 73.7
1915 Female, age 42, unknown 84.8
2410 Female, age 72, unknown 82.5
2218 Male, age 76, both hemispheres 75.2
1942 Male, age 51, unknown 69.5
2021 Male, age 53, unknown 65.9
2223 Female, age 72, unknown 64.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 70.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 70.3
Samples: 139

Max nTPM: 170.2
Min nTPM: 35.1
Std nTPM: 23.5
Median nTPM: 63.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 170.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 147.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 146.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 137.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 124.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 122.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 120.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 114.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 110.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 109.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 105.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 105.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 104.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 102.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 102.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 98.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 98.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 97.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 95.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 93.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 92.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 92.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 90.2
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 89.9
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 89.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 89.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 87.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 87.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 87.1
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 86.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 85.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 85.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 83.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 82.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 82.1
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 81.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 80.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 78.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 78.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 77.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 75.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 74.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 74.0
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 73.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 73.4
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 72.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 72.6
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 72.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 71.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 71.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 71.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 71.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 70.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 70.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 70.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 69.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 69.2
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 68.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 68.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 68.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 68.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 68.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 67.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 66.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 65.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 65.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 64.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 64.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 63.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 63.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 62.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 61.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 61.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 61.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 61.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 61.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 61.2
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 60.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 60.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 60.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 60.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 60.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 59.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 59.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 59.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 59.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 58.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 58.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 58.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 58.4
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 58.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 57.9
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 57.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 57.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 57.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 57.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 57.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 56.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 56.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 56.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 56.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 56.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 55.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 55.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 54.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 54.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 54.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 52.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 52.1
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 52.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 51.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 51.6
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 51.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 51.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 51.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 50.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 50.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 50.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 49.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 49.5
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 49.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 49.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 49.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 47.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 47.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 47.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 47.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 47.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 47.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 47.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 45.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 45.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 42.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 41.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 40.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 39.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 37.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 37.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 35.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 64.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 64.6
FF:10158-103A5 76 years, female 64.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 110.7
Pig sample Sample description nTPM
Midbrain
nTPM: 106.2
Samples: 4

Max nTPM: 119.6
Min nTPM: 96.2
Sample A Female 107.0
Sample B Female 96.2
Sample C Male 119.6
Sample D Male 102.0
Periaqueductal gray
nTPM: 92.6
Samples: 3

Max nTPM: 113.7
Min nTPM: 74.4
Sample B Female 89.6
Sample C Male 113.7
Sample D Male 74.4
Substantia nigra
nTPM: 110.7
Samples: 4

Max nTPM: 148.0
Min nTPM: 74.5
Sample A Female 148.0
Sample B Female 84.9
Sample C Male 135.4
Sample D Male 74.5
Superior colliculi
nTPM: 108.0
Samples: 4

Max nTPM: 126.0
Min nTPM: 82.4
Sample A Female 126.0
Sample B Female 82.4
Sample C Male 117.9
Sample D Male 105.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 160.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 160.2
Samples: 4

Max nTPM: 162.3
Min nTPM: 156.7
Sample A Male 156.7
Sample B Male 159.8
Sample C Female 162.0
Sample D Female 162.3

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 7.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.0
68157415 Antisense, RP_041116_02_F08, Mouse strain C57BL/6J (56 days, male) 7.0

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