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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:98.4 nTPM
HPA:98.4 nTPM
GTEx:78.9 nTPM
FANTOM5:83.5 Scaled Tags Per Million
Pig:5.4 nTPM
Mouse:51.2 nTPM
Allen mouse:6.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 98.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 94.9
2666 Male, age 74, left hemisphere 111.0
2586 Male, age 75, left hemisphere 96.8
2411 Female, age 72, unknown 96.7
2019 Male, age 18, unknown 94.6
1833 Male, age 53, unknown 93.6
1830 Male, age 51, unknown 93.4
2828 Female, age 72, unknown 92.7
1870 Female, age 42, unknown 92.2
1827 Male, age 72, unknown 91.9
2219 Male, age 76, both hemispheres 86.5
Dorsal raphe nucleus
nTPM: 93.6
1828 Male, age 53, unknown 96.7
2047 Male, age 72, unknown 94.7
2750 Male, age 76, both hemispheres 93.5
2298 Female, age 72, unknown 92.8
2016 Female, age 72, unknown 90.3
Inferior colliculus
nTPM: 91.7
1890 Male, age 53, unknown 93.0
2097 Female, age 72, unknown 92.5
2849 Male, age 72, unknown 90.9
1848 Female, age 42, unknown 90.5
Median raphe nucleus
nTPM: 95.7
2220 Male, age 76, midline 95.7
Pedunculopontine tegmental nucleus
nTPM: 91.6
2334 Male, age 80, both hemispheres 96.3
1921 Female, age 85, both hemispheres 91.7
2338 Male, age 61, both hemispheres 86.8
Periaquaductal grey, anterior
nTPM: 90.6
1947 Male, age 18, unknown 91.8
2502 Female, age 75, unknown 90.8
1795 Male, age 51, unknown 89.1
Periaquaductal grey, dorsal
nTPM: 89.3
2464 Female, age 72, unknown 90.4
2850 Male, age 76, both hemispheres 90.2
1831 Male, age 72, unknown 89.0
1840 Male, age 53, unknown 87.6
Periaquaductal grey, lateral
nTPM: 88.8
2140 Male, age 76, both hemispheres 90.6
2272 Male, age 74, both hemispheres 88.3
2053 Male, age 18, unknown 87.5
Pretectal area
nTPM: 92.0
1817 Female, age 42, unknown 95.7
1944 Female, age 72, unknown 95.3
1816 Male, age 51, unknown 94.4
2667 Female, age 75, unknown 94.1
2007 Male, age 72, unknown 93.9
1815 Male, age 53, unknown 93.8
2407 Male, age 75, both hemispheres 92.0
2825 Male, age 18, unknown 90.4
2224 Female, age 72, unknown 88.1
2316 Male, age 76, right hemisphere 88.0
2273 Male, age 74, both hemispheres 85.8
Red nucleus
nTPM: 96.9
1821 Female, age 72, unknown 102.5
1954 Female, age 42, unknown 101.7
1904 Male, age 53, unknown 98.8
2503 Female, age 72, unknown 98.8
1865 Male, age 51, unknown 97.6
2769 Male, age 72, unknown 96.3
2785 Male, age 18, unknown 96.3
2823 Male, age 76, right hemisphere 96.1
2227 Male, age 72, unknown 95.4
2584 Male, age 75, left hemisphere 94.5
2588 Male, age 74, left hemisphere 93.8
2725 Female, age 75, unknown 91.5
Substantia nigra
nTPM: 98.4
1916 Female, age 42, unknown 110.5
2409 Female, age 72, unknown 103.7
2241 Male, age 72, unknown 101.8
1851 Male, age 51, unknown 99.9
2699 Male, age 18, unknown 99.9
1889 Female, age 72, unknown 97.6
2583 Male, age 75, right hemisphere 97.2
1941 Male, age 53, unknown 94.3
2665 Male, age 74, both hemispheres 92.0
2590 Female, age 75, unknown 87.8
Superior colliculus
nTPM: 93.0
2668 Female, age 75, unknown 109.1
2087 Female, age 72, unknown 95.5
1796 Male, age 53, unknown 93.5
2261 Male, age 18, unknown 92.4
1913 Female, age 42, unknown 91.5
1995 Male, age 72, unknown 91.1
1839 Male, age 51, unknown 90.4
2587 Male, age 74, left hemisphere 89.0
2664 Male, age 75, both hemispheres 88.8
1895 Male, age 76, right hemisphere 88.6
Ventral tegmental area
nTPM: 94.9
1915 Female, age 42, unknown 101.0
2410 Female, age 72, unknown 99.7
1942 Male, age 51, unknown 94.2
2218 Male, age 76, both hemispheres 91.8
2223 Female, age 72, unknown 91.4
2021 Male, age 53, unknown 91.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 78.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 78.9
Samples: 139

Max nTPM: 338.5
Min nTPM: 36.0
Std nTPM: 48.0
Median nTPM: 64.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 338.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 329.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 260.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 223.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 202.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 191.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 177.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 170.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 162.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 156.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 146.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 131.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 131.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 130.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 128.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 122.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 113.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 106.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 106.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 103.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 102.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 101.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 99.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 96.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 96.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 92.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 90.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 90.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 87.9
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 87.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 86.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 86.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 85.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 84.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 82.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 82.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 81.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 81.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 80.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 80.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 80.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 80.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 79.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 79.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 75.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 74.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 74.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 73.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 72.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 71.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 71.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 71.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 70.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 70.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 70.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 69.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 69.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 68.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 67.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 67.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 67.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 67.0
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 67.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 66.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 66.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 65.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 65.9
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 65.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 65.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 64.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 64.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 63.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 63.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 63.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 63.0
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 62.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 62.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 61.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 61.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 61.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 61.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 60.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 60.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 60.5
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 59.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 58.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 58.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 58.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 58.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 57.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 57.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 57.7
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 57.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 57.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 57.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 57.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 55.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 55.8
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 55.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 55.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 54.0
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 53.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 53.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 52.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 52.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 52.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 52.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 52.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 52.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 51.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 50.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 50.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 50.4
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 49.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 49.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 49.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 49.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 47.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 47.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 47.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 47.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 47.0
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 46.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 46.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 45.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 45.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 45.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 45.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 44.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 44.4
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 43.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 43.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 42.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 42.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 40.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 39.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 39.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 36.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 36.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 83.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 83.5
FF:10158-103A5 76 years, female 83.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 5.4
Pig sample Sample description nTPM
Midbrain
nTPM: 4.8
Samples: 4

Max nTPM: 5.8
Min nTPM: 3.4
Sample A Female 4.2
Sample B Female 5.8
Sample C Male 3.4
Sample D Male 5.6
Periaqueductal gray
nTPM: 5.4
Samples: 3

Max nTPM: 5.8
Min nTPM: 5.2
Sample B Female 5.2
Sample C Male 5.2
Sample D Male 5.8
Substantia nigra
nTPM: 5.5
Samples: 4

Max nTPM: 7.6
Min nTPM: 3.9
Sample A Female 3.9
Sample B Female 4.1
Sample C Male 6.2
Sample D Male 7.6
Superior colliculi
nTPM: 4.4
Samples: 4

Max nTPM: 5.2
Min nTPM: 2.9
Sample A Female 2.9
Sample B Female 4.3
Sample C Male 5.0
Sample D Male 5.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 51.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 51.2
Samples: 4

Max nTPM: 53.9
Min nTPM: 48.1
Sample A Male 53.9
Sample B Male 48.1
Sample C Female 49.8
Sample D Female 52.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 6.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 6.9
564779 Antisense, RP_040826_01_F06, Mouse strain C57BL/6J (56 days, male) 6.9

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