Expression of RPLP2 in colorectal cancer

RECTUM ADENOCARCINOMA (READ) - Interactive survival scatter plotⁱ

The Survival Scatter plot shows the clinical status (i.e. dead or alive) for all individuals in the patient cohort, based on the same data that underlies the corresponding Kaplan-Meier plots. Patients that are alive at last time for follow-up are shown in blue and patients who have died during the study are shown in red.

The x-axis shows the expression levels (FPKM) of the investigated gene in the tumor tissue at the time of diagnosis. The y-axis shows the follow-up time after diagnosis (years). Both axes are complimented with kernel density curves demonstrating the data density over the axes. The top density plot shows the expression levels (FPKM) distribution among dead (red) and alive patients (blue). The right density plot shows the data density of the survived years of dead patients with high and low expression levels respectively, stratified using the cutoff indicated by the vertical dashed line through the Survival Scatter plot. This cutoff is automatically defined based on the FPKM cutoff that minimizes the p-score. The cutoff can be changed by dragging the vertical line or by entering a cutoff value in the square labeled "Current cut-off".

Under the Survival Scatter plot the p-score landscape (black curve; left axis) is shown together with dead median separation (red curve; right axis). Dead median separation is the difference in median mRNA expression between patients who have died with high and low expression, respectively. It is calculated as follows: median FPKM expression of dead patients with high expression - median FPKM expression of dead patients with low expression. This is intended to aid the user in visually exploring custom cutoffs and the associated p-scores and dead median separation.

Individual patient data is displayed and can be filtered by clicking on one or more of the category buttons on the top of the page. Categories describing expression level and patient information include: high, low, alive, dead, female, male and tumor stages. The scale of the x-axis can be toggled between linear and log-scale by clicking on the "x log" button. Mouse-over function shows TCGA ID, patient information and mRNA expression (FPKM) for each patient.

& Survival analysisⁱ

Stage:

Survival analysis

Current cut offⁱ :

Best expression cut offⁱ : 514.54

Median expressionⁱ : N/A

Median follow up timeⁱ : N/A

P scoreⁱ N/A

5-year survival highⁱ N/A

5-year survival lowⁱ N/A

TCGA RNA samplesⁱ

Average FPKM

560.9

Number of samples

159

Samples

Sample	Description	FPKM
TCGA-DC-6155-01A	31 years, female, white, stage:iiia, alive, 425 days	3534.2
TCGA-AG-3728-01A	73 years, male, stage:iiib, alive, 912 days	1202.9
TCGA-AG-3611-01A	72 years, male, stage:iia, alive, 424 days	1158.0
TCGA-AG-3591-01A	66 years, female, stage:iia, alive, 1035 days	1152.0
TCGA-DY-A1H8-01A	77 years, female, white, stage:iiia, dead, 992 days	1139.9
TCGA-AG-A02G-01A	66 years, male, stage:iv, dead, 1185 days	1114.0
TCGA-DY-A1DD-01A	77 years, female, white, stage:iiib, dead, 1741 days	1045.0
TCGA-AG-3605-01A	85 years, female, stage:iv, alive, 30 days	1041.0
TCGA-AG-3883-01A	69 years, male, stage:i, alive, 31 days	1028.5
TCGA-AG-3882-01A	66 years, female, stage:i, alive, 608 days	1019.0
TCGA-AG-3609-01A	65 years, female, stage:iiic, alive, 608 days	1012.5
TCGA-AG-3727-01A	78 years, female, stage:iii, alive, 30 days	978.6
TCGA-AG-3881-01A	83 years, female, stage:iia, alive, 579 days	961.1
TCGA-DY-A0XA-01A	57 years, female, white, stage:iia, alive, 3846 days	885.8
TCGA-AG-4007-01A	87 years, male, stage:iv, alive, 31 days	874.4
TCGA-AG-3999-01A	61 years, female, stage:iiic, alive, 853 days	843.9
TCGA-AG-3608-01A	79 years, female, stage:iia, alive, 485 days	791.8
TCGA-DY-A1DG-01A	75 years, male, white, stage:iva, dead, 1566 days	778.3
TCGA-EF-5830-01A	54 years, male, white, stage:iib, alive, 106 days	772.9
TCGA-AG-3612-01A	55 years, female, stage:iiib, alive, 608 days	771.3
TCGA-AG-A01N-01A	68 years, female, stage:iv, alive, 943 days	768.2
TCGA-G5-6233-01A	74 years, male, white, dead, 556 days	760.4
TCGA-AG-3887-01A	68 years, male, stage:iia, alive, 1124 days	757.4
TCGA-AG-3885-01A	71 years, female, stage:iiib, alive, 546 days	757.0
TCGA-AG-A00C-01A	49 years, female, stage:iiib, alive, 183 days	756.9
TCGA-BM-6198-01A	73 years, male, white, stage:iiib, alive, 646 days	755.1
TCGA-AG-3598-01A	69 years, male, stage:iia, alive, 1522 days	754.7
TCGA-DC-4745-01A	49 years, female, white, stage:iiib, alive, 639 days	754.5
TCGA-AG-3583-01A	66 years, male, stage:iv, dead, 610 days	748.0
TCGA-AG-3726-01A	63 years, female, stage:i, alive, 243 days	720.3
TCGA-AG-4005-01A	64 years, male, stage:iv, alive, 427 days	707.7
TCGA-AG-3587-01A	65 years, male, stage:i, alive, 1400 days	704.5
TCGA-EI-7002-01A	58 years, male, white, stage:iv, alive, 364 days	702.7
TCGA-EI-6883-01A	63 years, male, white, stage:iic, alive, 350 days	698.9
TCGA-CL-5918-01A	90 years, female, white, stage:iia, alive, 218 days	690.2
TCGA-AG-3909-01A	69 years, female, stage:iiib, alive, 608 days	688.7
TCGA-DC-4749-01A	57 years, male, white, stage:i, alive, 762 days	680.1
TCGA-AG-3902-01A	61 years, male, stage:iia, alive, 974 days	679.0
TCGA-AG-3574-01A	89 years, female, stage:ii, dead, 1096 days	666.8
TCGA-AG-A023-01A	62 years, female, stage:iv, dead, 1581 days	656.6
TCGA-DC-6154-01A	57 years, female, white, stage:iva, alive, 365 days	655.6
TCGA-AG-A025-01A	62 years, female, stage:i, alive, 1520 days	647.5
TCGA-AG-3894-01A	65 years, male, stage:iia, alive, 426 days	642.0
TCGA-AF-3913-01A	60 years, male, black or african american, stage:iv, dead, 316 days	640.8
TCGA-G5-6641-01A	67 years, male, white, stage:iiia, alive, 804 days	638.2
TCGA-AF-2693-01A	75 years, male, white, stage:i, alive, 1155 days	627.6
TCGA-AG-A02X-01A	77 years, male, stage:i, alive, 1247 days	622.5
TCGA-DC-5869-01A	62 years, female, black or african american, stage:iiib, alive, 943 days	618.8
TCGA-DC-6682-01A	57 years, male, white, stage:iia, alive, 762 days	615.4
TCGA-AF-4110-01A	77 years, male, white, stage:iva, alive, 912 days	613.3
TCGA-AG-A00Y-01A	68 years, male, stage:iia, alive, 700 days	610.7
TCGA-AG-3725-01A	90 years, female, stage:iii, alive, 638 days	605.6
TCGA-CI-6623-01B	44 years, male, white, stage:i, alive, 1443 days	604.9
TCGA-AG-3896-01A	85 years, female, stage:i, alive, 31 days	604.2
TCGA-AG-3878-01A	64 years, male, stage:i, alive, 30 days	603.6
TCGA-DC-5337-01A	69 years, male, white, stage:i, alive, 792 days	589.8
TCGA-F5-6863-01A	71 years, female, white, stage:iiib, dead, 361 days	589.2
TCGA-AG-A00H-01A	75 years, male, stage:iia, alive, 790 days	577.2
TCGA-AH-6897-01A	48 years, male, white, stage:i, alive, 804 days	576.0
TCGA-AF-A56L-01A	48 years, female, black or african american, stage:iiic, alive, 2007 days	570.5
TCGA-AF-6672-01A	43 years, male, white, stage:iv, alive, 748 days	558.4
TCGA-AG-3582-01A	75 years, male, stage:iv, dead, 1096 days	552.6
TCGA-AF-2691-01A	48 years, female, white, stage:i, alive, 1309 days	546.2
TCGA-AG-A01J-01A	59 years, female, stage:iia, alive, 31 days	541.3
TCGA-CL-4957-01A	79 years, female, dead, 425 days	538.4
TCGA-AG-3599-01A	70 years, male, stage:i, alive, 366 days	533.9
TCGA-AG-4001-01A	74 years, female, stage:iia, alive, 1096 days	532.5
TCGA-DY-A1DC-01A	72 years, female, white, stage:iia, dead, 1258 days	529.6
TCGA-AG-A036-01A	71 years, male, stage:iii, alive, 3562 days	524.0
TCGA-AG-3575-01A	51 years, male, stage:ii, alive, 365 days	517.9
TCGA-AF-2690-01A	77 years, female, white, stage:iiic, dead, 524 days	517.7
TCGA-AF-5654-01A	73 years, female, white, stage:i, dead, 512 days	514.6
TCGA-DT-5265-01A	51 years, male, asian, stage:ii, alive, 384 days	514.4
TCGA-DC-6160-01A	68 years, male, white, stage:i, alive, 1339 days	513.4
TCGA-DC-6681-01A	70 years, female, white, stage:iva, alive, 790 days	512.0
TCGA-DY-A1DE-01A	56 years, female, white, stage:iia, alive, 3932 days	510.6
TCGA-AG-3898-01A	61 years, male, stage:iia, alive, 1461 days	508.8
TCGA-CI-6620-01A	41 years, female, white, stage:iva, alive, 1009 days	504.6
TCGA-F5-6861-01A	60 years, female, white, stage:iia, alive, 1160 days	502.3
TCGA-EF-5831-01A	72 years, male, white, stage:iia, alive, 127 days	501.3
TCGA-AG-A032-01A	68 years, male, stage:iiib, alive, 1157 days	500.5
TCGA-AG-3892-01A	57 years, female, stage:i, alive, 396 days	499.6
TCGA-AF-6655-01A	66 years, male, white, stage:iiia, alive, 609 days	492.3
TCGA-CI-6619-01B	41 years, male, white, stage:iv, alive, 184 days	489.8
TCGA-EI-6513-01A	59 years, male, white, stage:iiib, alive, 497 days	482.6
TCGA-CI-6622-01A	74 years, male, white, stage:iib, alive, 1362 days	481.6
TCGA-AG-3584-01A	60 years, male, stage:iv, dead, 730 days	480.7
TCGA-F5-6864-01A	74 years, female, white, stage:iiib, alive, 379 days	476.7
TCGA-AG-3592-01A	68 years, male, stage:iia, alive, 1035 days	476.6
TCGA-AG-3893-01A	74 years, male, stage:iiib, alive, 1065 days	473.9
TCGA-AG-3594-01A	77 years, male, stage:iia, dead, 61 days	467.2
TCGA-G5-6572-01A	56 years, male, white, dead, 1432 days	466.3
TCGA-EI-6514-01A	59 years, female, white, stage:iia, alive, 496 days	465.3
TCGA-AF-6136-01A	72 years, female, white, stage:iiib, alive, 741 days	464.2
TCGA-AG-3586-01A	72 years, female, stage:iii, alive, 31 days	463.2
TCGA-F5-6571-01A	62 years, female, white, stage:iia, alive, 1288 days	460.7
TCGA-AG-A014-01A	86 years, male, stage:i, alive, 485 days	460.6
TCGA-AG-3600-01A	62 years, male, stage:iiic, alive, 184 days	460.5
TCGA-AG-3580-01A	67 years, male, stage:i, alive, 244 days	455.2
TCGA-AG-A008-01A	50 years, female, stage:i, alive, 424 days	453.0
TCGA-EI-6917-01A	33 years, male, white, stage:iiia, alive, 531 days	452.8
TCGA-DC-6157-01A	48 years, male, black or african american, stage:i, alive, 1581 days	443.0
TCGA-AF-3911-01A	48 years, male, white, stage:iiic, alive, 1148 days	442.3
TCGA-AG-3890-01A	62 years, male, stage:i, alive, 518 days	441.3
TCGA-AF-A56N-01A	47 years, female, black or african american, stage:iia, alive, 360 days	437.7
TCGA-AG-A026-01A	66 years, male, stage:ii, dead, 59 days	434.4
TCGA-AF-A56K-01A	56 years, male, black or african american, stage:iia, alive, 2635 days	426.3
TCGA-AG-3742-01A	85 years, female, stage:i, alive, 30 days	424.7
TCGA-CI-6621-01A	63 years, male, white, stage:iiib, alive, 419 days	424.3
TCGA-AG-A015-01A	64 years, female, stage:i, alive, 1096 days	422.3
TCGA-G5-6235-01A	72 years, male, white, stage:iiib, alive, 1696 days	420.9
TCGA-F5-6812-01A	67 years, male, white, stage:iia, alive, 1110 days	419.1
TCGA-F5-6814-01A	57 years, male, white, stage:iia, alive, 1131 days	414.5
TCGA-AH-6544-01A	60 years, male, white, alive, 1173 days	413.6
TCGA-AG-4008-01A	63 years, male, stage:iia, alive, 518 days	411.5
TCGA-AG-A016-01A	55 years, male, stage:iv, alive, 276 days	407.6
TCGA-EI-6881-01A	60 years, male, white, stage:iiia, alive, 499 days	406.9
TCGA-EI-6507-01A	60 years, male, white, stage:iia, alive, 607 days	398.7
TCGA-AG-3593-01A	72 years, female, stage:iia, alive, 1035 days	397.9
TCGA-EI-6506-01A	78 years, female, white, stage:iia, alive, 625 days	397.6
TCGA-AG-4022-01A	59 years, female, stage:ii, alive, 1400 days	394.2
TCGA-AG-A020-01A	57 years, female, stage:iii, alive, 31 days	391.7
TCGA-EI-6511-01A	52 years, male, white, stage:iiib, alive, 482 days	389.7
TCGA-DY-A1DF-01A	73 years, female, white, stage:iiic, dead, 734 days	387.0
TCGA-DC-6683-01A	43 years, male, white, stage:iiib, alive, 762 days	386.4
TCGA-EI-6510-01A	77 years, female, white, alive, 556 days	386.2
TCGA-F5-6811-01A	72 years, female, white, stage:iia, alive, 979 days	380.5
TCGA-EI-6884-01A	71 years, male, white, stage:iiia, alive, 328 days	373.9
TCGA-AG-3581-01A	63 years, male, stage:i, alive, 215 days	367.7
TCGA-AF-2687-01A	57 years, male, white, stage:iiic, alive, 1427 days	361.5
TCGA-AF-2692-01A	54 years, female, white, stage:iia, alive, 412 days	359.7
TCGA-AH-6903-01A	46 years, male, white, stage:iiib, alive, 592 days	348.9
TCGA-AF-3400-01A	54 years, male, white, stage:iia, alive, 1049 days	339.9
TCGA-EI-6512-01A	64 years, female, white, stage:iiib, alive, 538 days	335.4
TCGA-AG-3901-01A	67 years, female, stage:iiib, alive, 761 days	334.9
TCGA-AG-4021-01A	84 years, female, stage:iv, dead, 121 days	324.9
TCGA-AG-3731-01A	65 years, male, stage:iv, alive, 1126 days	320.9
TCGA-AH-6644-01A	73 years, male, white, alive, 838 days	313.9
TCGA-EI-6508-01A	48 years, female, white, stage:iiib, alive, 636 days	309.7
TCGA-F5-6702-01A	71 years, male, white, stage:iva, alive, 869 days	305.8
TCGA-AG-A02N-01A	67 years, male, stage:ii, alive, 1885 days	303.6
TCGA-EI-6885-01A	57 years, female, white, stage:iv, alive, 415 days	301.4
TCGA-F5-6813-01A	70 years, male, white, stage:iiic, dead, 598 days	297.1
TCGA-AH-6643-01A	50 years, male, white, stage:iiic, dead, 1314 days	292.1
TCGA-AG-3732-01A	78 years, female, stage:i, alive, 1003 days	291.8
TCGA-EI-6509-01A	53 years, male, white, stage:iiic, alive, 517 days	291.3
TCGA-AH-6547-01A	79 years, female, white, dead, 76 days	271.8
TCGA-F5-6465-01A	64 years, female, white, stage:iia, alive, 1506 days	269.1
TCGA-AG-A011-01A	80 years, male, stage:iia, alive, 1126 days	267.7
TCGA-AH-6549-01A	66 years, male, white, alive, 532 days	264.3
TCGA-EI-7004-01A	37 years, female, white, alive, 257 days	256.5
TCGA-F5-6464-01A	77 years, female, white, stage:iiic, dead, 303 days	252.6
TCGA-DC-6158-01A	70 years, male, white, stage:i, dead, 334 days	251.0
TCGA-AG-3578-01A	76 years, female, stage:iia, alive, 974 days	245.6
TCGA-EI-6882-01A	59 years, male, white, stage:iia, alive, 262 days	241.7
TCGA-CI-6624-01C	53 years, female, white, stage:i, alive, 1466 days	234.5
TCGA-CL-5917-01A	71 years, female, white, stage:iiic, alive, 2376 days	225.5
TCGA-DC-6156-01A	62 years, male, white, stage:iva, alive, 943 days	191.1
TCGA-AG-A002-01A	35 years, male, stage:i, alive, 638 days	184.4
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