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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:155.6 nTPM
HPA:155.6 nTPM
GTEx:222.2 nTPM
FANTOM5:251.7 Scaled Tags Per Million
Pig:136.3 nTPM
Mouse:249.1 nTPM
Allen mouse:11.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 155.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 147.1
2586 Male, age 75, left hemisphere 230.5
2828 Female, age 72, unknown 158.6
2019 Male, age 18, unknown 157.6
1827 Male, age 72, unknown 151.6
2666 Male, age 74, left hemisphere 137.0
1833 Male, age 53, unknown 136.9
1870 Female, age 42, unknown 130.9
2219 Male, age 76, both hemispheres 126.7
1830 Male, age 51, unknown 126.4
2411 Female, age 72, unknown 115.3
Dorsal raphe nucleus
nTPM: 140.0
2047 Male, age 72, unknown 155.8
2298 Female, age 72, unknown 146.1
1828 Male, age 53, unknown 144.1
2016 Female, age 72, unknown 127.8
2750 Male, age 76, both hemispheres 126.4
Inferior colliculus
nTPM: 147.0
2849 Male, age 72, unknown 162.9
1848 Female, age 42, unknown 144.7
2097 Female, age 72, unknown 140.3
1890 Male, age 53, unknown 140.2
Median raphe nucleus
nTPM: 155.6
2220 Male, age 76, midline 155.6
Pedunculopontine tegmental nucleus
nTPM: 134.5
2334 Male, age 80, both hemispheres 138.4
2338 Male, age 61, both hemispheres 133.3
1921 Female, age 85, both hemispheres 131.9
Periaquaductal grey, anterior
nTPM: 145.2
1795 Male, age 51, unknown 157.1
1947 Male, age 18, unknown 143.6
2502 Female, age 75, unknown 134.9
Periaquaductal grey, dorsal
nTPM: 142.5
2850 Male, age 76, both hemispheres 157.1
1840 Male, age 53, unknown 148.3
1831 Male, age 72, unknown 136.4
2464 Female, age 72, unknown 128.2
Periaquaductal grey, lateral
nTPM: 135.3
2140 Male, age 76, both hemispheres 142.0
2272 Male, age 74, both hemispheres 139.5
2053 Male, age 18, unknown 124.4
Pretectal area
nTPM: 154.3
1817 Female, age 42, unknown 182.0
1816 Male, age 51, unknown 173.4
1944 Female, age 72, unknown 166.5
2007 Male, age 72, unknown 166.2
2407 Male, age 75, both hemispheres 158.9
2667 Female, age 75, unknown 157.9
1815 Male, age 53, unknown 157.1
2273 Male, age 74, both hemispheres 148.6
2224 Female, age 72, unknown 137.7
2825 Male, age 18, unknown 137.3
2316 Male, age 76, right hemisphere 111.6
Red nucleus
nTPM: 135.6
2584 Male, age 75, left hemisphere 160.0
2785 Male, age 18, unknown 153.3
2725 Female, age 75, unknown 142.6
1821 Female, age 72, unknown 136.9
1954 Female, age 42, unknown 135.8
2769 Male, age 72, unknown 134.6
1865 Male, age 51, unknown 132.4
2503 Female, age 72, unknown 129.2
2227 Male, age 72, unknown 127.7
2823 Male, age 76, right hemisphere 126.3
1904 Male, age 53, unknown 126.1
2588 Male, age 74, left hemisphere 122.0
Substantia nigra
nTPM: 155.2
1916 Female, age 42, unknown 178.5
2583 Male, age 75, right hemisphere 177.1
2665 Male, age 74, both hemispheres 166.8
1941 Male, age 53, unknown 164.3
1889 Female, age 72, unknown 157.4
1851 Male, age 51, unknown 155.7
2699 Male, age 18, unknown 151.8
2590 Female, age 75, unknown 142.7
2409 Female, age 72, unknown 130.6
2241 Male, age 72, unknown 127.4
Superior colliculus
nTPM: 147.9
2664 Male, age 75, both hemispheres 201.1
1796 Male, age 53, unknown 156.7
2087 Female, age 72, unknown 156.1
2668 Female, age 75, unknown 155.1
2261 Male, age 18, unknown 145.3
1995 Male, age 72, unknown 138.1
1839 Male, age 51, unknown 137.5
2587 Male, age 74, left hemisphere 135.6
1913 Female, age 42, unknown 129.0
1895 Male, age 76, right hemisphere 124.1
Ventral tegmental area
nTPM: 140.5
1915 Female, age 42, unknown 148.9
2218 Male, age 76, both hemispheres 144.6
1942 Male, age 51, unknown 140.3
2410 Female, age 72, unknown 139.8
2223 Female, age 72, unknown 138.9
2021 Male, age 53, unknown 130.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 222.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 222.2
Samples: 139

Max nTPM: 626.9
Min nTPM: 77.2
Std nTPM: 80.6
Median nTPM: 211.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 626.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 474.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 464.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 430.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 414.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 397.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 390.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 369.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 367.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 346.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 343.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 325.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 321.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 315.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 315.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 315.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 306.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 305.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 301.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 299.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 295.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 284.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 277.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 276.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 271.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 268.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 266.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 265.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 265.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 264.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 263.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 261.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 258.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 258.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 254.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 252.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 250.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 249.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 246.6
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 245.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 242.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 242.0
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 240.9
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 239.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 239.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 238.7
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 237.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 237.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 236.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 235.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 231.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 230.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 227.1
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 226.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 226.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 225.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 225.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 222.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 221.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 220.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 219.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 218.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 216.1
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 215.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 214.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 213.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 213.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 213.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 212.2
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 211.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 210.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 207.6
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 207.3
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 206.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 205.3
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 205.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 203.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 203.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 200.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 200.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 199.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 199.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 196.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 196.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 192.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 190.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 190.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 190.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 189.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 185.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 184.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 184.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 183.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 181.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 179.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 176.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 175.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 175.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 175.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 174.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 173.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 172.7
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 169.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 168.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 168.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 168.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 166.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 166.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 161.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 160.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 158.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 156.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 155.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 154.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 153.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 153.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 153.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 152.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 151.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 151.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 150.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 148.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 148.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 144.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 143.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 143.3
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 141.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 138.9
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 138.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 138.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 134.1
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 127.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 124.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 105.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 102.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 101.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 95.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 92.9
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 77.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 251.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 251.7
FF:10158-103A5 76 years, female 251.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 136.3
Pig sample Sample description nTPM
Midbrain
nTPM: 117.3
Samples: 4

Max nTPM: 193.8
Min nTPM: 73.8
Sample A Female 73.8
Sample B Female 75.9
Sample C Male 193.8
Sample D Male 125.5
Periaqueductal gray
nTPM: 84.7
Samples: 3

Max nTPM: 112.3
Min nTPM: 67.4
Sample B Female 67.4
Sample C Male 112.3
Sample D Male 74.5
Substantia nigra
nTPM: 95.4
Samples: 4

Max nTPM: 128.6
Min nTPM: 50.9
Sample A Female 128.6
Sample B Female 75.5
Sample C Male 126.4
Sample D Male 50.9
Superior colliculi
nTPM: 136.3
Samples: 4

Max nTPM: 183.7
Min nTPM: 83.6
Sample A Female 145.3
Sample B Female 83.6
Sample C Male 183.7
Sample D Male 132.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 249.1
Mouse sample Sample description nTPM
Midbrain
nTPM: 249.1
Samples: 4

Max nTPM: 263.8
Min nTPM: 240.3
Sample A Male 245.1
Sample B Male 240.3
Sample C Female 263.8
Sample D Female 247.1

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 11.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 11.6
68162255 Antisense, RP_041122_02_E12, Mouse strain C57BL/6J (56 days, male) 21.9
1948 Antisense, RP_040507_01_F08, Mouse strain C57BL/6J (56 days, male) 1.2

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