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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:207.5 nTPM
HPA:207.5 nTPM
GTEx:285.6 nTPM
FANTOM5:139.0 Scaled Tags Per Million
Pig:130.5 nTPM
Mouse:484.9 nTPM
Allen mouse:10.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 207.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 182.1
2019 Male, age 18, unknown 215.0
1827 Male, age 72, unknown 184.4
2219 Male, age 76, both hemispheres 181.9
2828 Female, age 72, unknown 180.9
2586 Male, age 75, left hemisphere 180.4
1833 Male, age 53, unknown 179.3
1870 Female, age 42, unknown 178.1
2411 Female, age 72, unknown 177.9
1830 Male, age 51, unknown 171.8
2666 Male, age 74, left hemisphere 171.7
Dorsal raphe nucleus
nTPM: 184.8
1828 Male, age 53, unknown 201.2
2298 Female, age 72, unknown 190.1
2047 Male, age 72, unknown 187.1
2750 Male, age 76, both hemispheres 180.3
2016 Female, age 72, unknown 165.4
Inferior colliculus
nTPM: 186.8
1890 Male, age 53, unknown 196.8
2097 Female, age 72, unknown 191.0
1848 Female, age 42, unknown 187.8
2849 Male, age 72, unknown 171.6
Median raphe nucleus
nTPM: 179.2
2220 Male, age 76, midline 179.2
Pedunculopontine tegmental nucleus
nTPM: 182.8
2334 Male, age 80, both hemispheres 186.4
1921 Female, age 85, both hemispheres 186.1
2338 Male, age 61, both hemispheres 175.7
Periaquaductal grey, anterior
nTPM: 177.8
1947 Male, age 18, unknown 181.6
1795 Male, age 51, unknown 179.8
2502 Female, age 75, unknown 171.9
Periaquaductal grey, dorsal
nTPM: 168.4
1831 Male, age 72, unknown 174.2
2850 Male, age 76, both hemispheres 170.8
1840 Male, age 53, unknown 166.1
2464 Female, age 72, unknown 162.4
Periaquaductal grey, lateral
nTPM: 173.7
2272 Male, age 74, both hemispheres 190.4
2053 Male, age 18, unknown 167.0
2140 Male, age 76, both hemispheres 163.7
Pretectal area
nTPM: 200.1
1817 Female, age 42, unknown 231.0
2007 Male, age 72, unknown 230.8
1944 Female, age 72, unknown 226.6
1816 Male, age 51, unknown 219.3
2667 Female, age 75, unknown 213.7
1815 Male, age 53, unknown 201.2
2273 Male, age 74, both hemispheres 188.6
2224 Female, age 72, unknown 176.3
2407 Male, age 75, both hemispheres 173.8
2825 Male, age 18, unknown 170.3
2316 Male, age 76, right hemisphere 169.2
Red nucleus
nTPM: 196.4
1821 Female, age 72, unknown 223.0
2725 Female, age 75, unknown 208.7
2785 Male, age 18, unknown 208.5
1865 Male, age 51, unknown 196.6
2503 Female, age 72, unknown 194.8
2823 Male, age 76, right hemisphere 193.5
2769 Male, age 72, unknown 193.4
1954 Female, age 42, unknown 193.3
2588 Male, age 74, left hemisphere 191.3
2227 Male, age 72, unknown 189.4
1904 Male, age 53, unknown 185.1
2584 Male, age 75, left hemisphere 178.9
Substantia nigra
nTPM: 207.5
1916 Female, age 42, unknown 240.8
1889 Female, age 72, unknown 224.2
1941 Male, age 53, unknown 217.9
1851 Male, age 51, unknown 213.7
2409 Female, age 72, unknown 209.2
2241 Male, age 72, unknown 209.1
2665 Male, age 74, both hemispheres 194.4
2699 Male, age 18, unknown 193.6
2590 Female, age 75, unknown 191.0
2583 Male, age 75, right hemisphere 181.1
Superior colliculus
nTPM: 182.1
2087 Female, age 72, unknown 212.2
1895 Male, age 76, right hemisphere 197.8
2587 Male, age 74, left hemisphere 189.6
1796 Male, age 53, unknown 184.5
2261 Male, age 18, unknown 182.1
2668 Female, age 75, unknown 176.9
1839 Male, age 51, unknown 175.0
1913 Female, age 42, unknown 168.9
2664 Male, age 75, both hemispheres 167.9
1995 Male, age 72, unknown 166.2
Ventral tegmental area
nTPM: 190.2
2410 Female, age 72, unknown 207.5
1915 Female, age 42, unknown 203.9
2218 Male, age 76, both hemispheres 202.1
2223 Female, age 72, unknown 183.0
1942 Male, age 51, unknown 179.8
2021 Male, age 53, unknown 164.9

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 285.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 285.6
Samples: 139

Max nTPM: 564.8
Min nTPM: 135.9
Std nTPM: 81.8
Median nTPM: 272.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 564.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 505.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 504.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 491.5
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 487.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 459.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 445.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 444.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 430.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 422.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 417.9
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 415.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 411.2
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 410.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 409.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 398.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 398.2
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 395.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 394.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 382.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 372.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 369.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 364.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 363.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 355.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 351.7
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 347.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 343.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 341.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 339.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 336.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 336.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 332.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 330.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 328.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 327.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 324.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 322.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 322.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 320.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 314.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 313.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 312.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 308.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 306.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 303.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 301.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 300.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 299.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 296.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 294.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 294.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 294.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 293.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 292.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 291.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 291.2
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 291.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 290.6
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 284.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 284.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 283.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 280.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 279.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 279.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 279.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 274.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 274.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 272.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 272.2
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 269.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 269.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 269.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 268.3
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 266.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 265.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 261.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 259.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 257.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 255.8
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 255.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 252.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 251.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 251.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 249.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 248.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 248.5
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 246.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 245.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 243.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 243.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 243.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 243.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 240.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 235.9
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 234.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 233.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 233.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 233.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 232.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 230.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 224.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 224.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 222.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 219.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 218.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 217.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 216.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 215.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 215.1
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 213.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 212.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 212.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 212.5
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 209.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 208.9
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 208.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 208.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 207.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 205.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 204.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 202.4
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 202.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 201.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 200.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 199.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 198.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 197.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 192.6
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 189.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 187.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 187.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 184.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 172.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 171.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 168.3
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 163.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 155.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 135.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 139.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 139.0
FF:10158-103A5 76 years, female 139.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 130.5
Pig sample Sample description nTPM
Midbrain
nTPM: 106.6
Samples: 4

Max nTPM: 139.5
Min nTPM: 87.6
Sample A Female 89.6
Sample B Female 87.6
Sample C Male 139.5
Sample D Male 109.6
Periaqueductal gray
nTPM: 80.5
Samples: 3

Max nTPM: 98.9
Min nTPM: 66.8
Sample B Female 75.8
Sample C Male 98.9
Sample D Male 66.8
Substantia nigra
nTPM: 89.6
Samples: 4

Max nTPM: 137.5
Min nTPM: 59.9
Sample A Female 137.5
Sample B Female 62.6
Sample C Male 98.2
Sample D Male 59.9
Superior colliculi
nTPM: 130.5
Samples: 4

Max nTPM: 174.2
Min nTPM: 70.5
Sample A Female 164.2
Sample B Female 70.5
Sample C Male 174.2
Sample D Male 113.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 484.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 484.9
Samples: 4

Max nTPM: 502.9
Min nTPM: 462.2
Sample A Male 502.9
Sample B Male 487.1
Sample C Female 462.2
Sample D Female 487.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 10.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.7
70445676 Antisense, RP_050614_04_D01, Mouse strain C57BL/6J (56 days, male) 10.7

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