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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:101.7 nTPM
HPA:101.7 nTPM
GTEx:198.9 nTPM
FANTOM5:111.5 Scaled Tags Per Million
Pig:161.2 nTPM
Mouse:219.5 nTPM
Allen mouse:1.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 101.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 96.6
2411 Female, age 72, unknown 103.1
2019 Male, age 18, unknown 101.7
1827 Male, age 72, unknown 100.6
2219 Male, age 76, both hemispheres 96.5
1870 Female, age 42, unknown 96.0
2828 Female, age 72, unknown 95.4
1833 Male, age 53, unknown 94.7
1830 Male, age 51, unknown 93.7
2586 Male, age 75, left hemisphere 92.9
2666 Male, age 74, left hemisphere 91.2
Dorsal raphe nucleus
nTPM: 98.4
2298 Female, age 72, unknown 103.5
2750 Male, age 76, both hemispheres 100.0
1828 Male, age 53, unknown 97.1
2047 Male, age 72, unknown 96.9
2016 Female, age 72, unknown 94.2
Inferior colliculus
nTPM: 96.0
2097 Female, age 72, unknown 100.2
1848 Female, age 42, unknown 96.3
1890 Male, age 53, unknown 95.7
2849 Male, age 72, unknown 91.8
Median raphe nucleus
nTPM: 96.6
2220 Male, age 76, midline 96.6
Pedunculopontine tegmental nucleus
nTPM: 98.7
2338 Male, age 61, both hemispheres 99.5
2334 Male, age 80, both hemispheres 98.8
1921 Female, age 85, both hemispheres 97.7
Periaquaductal grey, anterior
nTPM: 98.5
1795 Male, age 51, unknown 99.5
1947 Male, age 18, unknown 98.3
2502 Female, age 75, unknown 97.7
Periaquaductal grey, dorsal
nTPM: 93.9
1840 Male, age 53, unknown 95.3
2464 Female, age 72, unknown 95.2
1831 Male, age 72, unknown 92.6
2850 Male, age 76, both hemispheres 92.3
Periaquaductal grey, lateral
nTPM: 95.6
2272 Male, age 74, both hemispheres 102.4
2053 Male, age 18, unknown 92.6
2140 Male, age 76, both hemispheres 91.9
Pretectal area
nTPM: 98.9
1817 Female, age 42, unknown 103.4
2007 Male, age 72, unknown 103.2
1816 Male, age 51, unknown 101.7
2273 Male, age 74, both hemispheres 101.5
1815 Male, age 53, unknown 100.9
1944 Female, age 72, unknown 100.1
2667 Female, age 75, unknown 98.9
2316 Male, age 76, right hemisphere 97.2
2224 Female, age 72, unknown 95.9
2825 Male, age 18, unknown 93.8
2407 Male, age 75, both hemispheres 91.0
Red nucleus
nTPM: 97.7
1821 Female, age 72, unknown 102.2
2503 Female, age 72, unknown 101.2
2785 Male, age 18, unknown 101.1
2725 Female, age 75, unknown 100.0
1865 Male, age 51, unknown 97.9
2227 Male, age 72, unknown 97.3
1904 Male, age 53, unknown 97.0
2769 Male, age 72, unknown 97.0
2823 Male, age 76, right hemisphere 96.1
1954 Female, age 42, unknown 95.3
2588 Male, age 74, left hemisphere 94.5
2584 Male, age 75, left hemisphere 92.6
Substantia nigra
nTPM: 101.7
1916 Female, age 42, unknown 109.2
1851 Male, age 51, unknown 105.3
2241 Male, age 72, unknown 105.1
2665 Male, age 74, both hemispheres 101.6
1889 Female, age 72, unknown 101.2
2409 Female, age 72, unknown 101.2
2590 Female, age 75, unknown 101.2
1941 Male, age 53, unknown 101.1
2699 Male, age 18, unknown 98.8
2583 Male, age 75, right hemisphere 92.7
Superior colliculus
nTPM: 97.0
1796 Male, age 53, unknown 101.8
2087 Female, age 72, unknown 100.1
2587 Male, age 74, left hemisphere 100.0
2261 Male, age 18, unknown 99.1
1895 Male, age 76, right hemisphere 97.4
1839 Male, age 51, unknown 95.3
2668 Female, age 75, unknown 95.2
1913 Female, age 42, unknown 94.3
1995 Male, age 72, unknown 94.0
2664 Male, age 75, both hemispheres 92.8
Ventral tegmental area
nTPM: 99.0
1915 Female, age 42, unknown 103.4
2410 Female, age 72, unknown 102.6
2218 Male, age 76, both hemispheres 99.7
2223 Female, age 72, unknown 98.1
1942 Male, age 51, unknown 96.0
2021 Male, age 53, unknown 94.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 198.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 198.9
Samples: 139

Max nTPM: 431.6
Min nTPM: 120.6
Std nTPM: 41.1
Median nTPM: 191.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 431.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 323.2
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 310.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 309.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 308.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 285.8
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 283.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 273.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 265.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 265.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 253.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 251.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 249.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 244.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 244.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 241.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 238.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 236.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 234.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 234.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 230.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 230.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 226.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 224.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 224.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 221.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 219.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 219.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 218.1
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 217.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 214.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 214.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 214.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 214.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 213.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 212.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 212.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 212.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 212.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 211.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 211.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 210.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 209.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 209.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 209.4
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 208.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 207.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 207.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 206.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 206.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 206.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 206.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 205.9
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 203.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 203.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 203.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 201.8
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 198.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 196.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 196.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 196.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 196.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 196.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 194.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 194.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 194.5
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 194.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 193.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 192.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 191.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 190.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 190.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 189.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 189.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 189.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 189.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 188.6
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 185.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 185.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 185.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 184.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 183.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 182.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 182.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 181.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 181.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 181.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 180.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 180.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 177.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 177.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 177.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 177.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 176.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 175.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 175.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 175.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 174.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 174.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 173.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 173.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 173.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 173.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 172.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 172.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 172.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 172.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 172.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 171.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 171.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 171.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 171.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 171.3
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 171.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 171.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 170.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 168.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 167.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 165.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 165.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 165.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 165.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 163.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 162.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 158.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 157.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 156.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 155.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 154.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 154.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 153.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 151.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 151.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 150.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 148.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 136.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 134.6
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 131.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 120.6
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 111.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 111.5
FF:10158-103A5 76 years, female 111.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 161.2
Pig sample Sample description nTPM
Midbrain
nTPM: 159.2
Samples: 4

Max nTPM: 241.2
Min nTPM: 120.8
Sample A Female 241.2
Sample B Female 152.2
Sample C Male 122.7
Sample D Male 120.8
Periaqueductal gray
nTPM: 125.8
Samples: 3

Max nTPM: 131.4
Min nTPM: 115.0
Sample B Female 131.0
Sample C Male 131.4
Sample D Male 115.0
Substantia nigra
nTPM: 155.5
Samples: 4

Max nTPM: 205.9
Min nTPM: 123.3
Sample A Female 205.9
Sample B Female 148.8
Sample C Male 123.3
Sample D Male 144.0
Superior colliculi
nTPM: 161.2
Samples: 4

Max nTPM: 198.6
Min nTPM: 136.2
Sample A Female 198.6
Sample B Female 170.2
Sample C Male 136.2
Sample D Male 139.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 219.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 219.5
Samples: 4

Max nTPM: 238.3
Min nTPM: 203.3
Sample A Male 238.3
Sample B Male 208.5
Sample C Female 203.3
Sample D Female 227.9

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 1.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 1.4
68910971 Antisense, RP_050118_02_H06, Mouse strain C57BL/6J (56 days, male) 1.4

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