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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
PRIMARY MOUSE DATA
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:59.1 nTPM
HPA:59.1 nTPM
GTEx:63.4 nTPM
FANTOM5:91.5 Scaled Tags Per Million
Pig:33.3 nTPM
Mouse:35.6 nTPM
Allen mouse:10.9 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 59.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 49.2
2411 Female, age 72, unknown 59.3
2019 Male, age 18, unknown 56.9
1830 Male, age 51, unknown 55.7
1833 Male, age 53, unknown 53.3
1870 Female, age 42, unknown 51.7
2828 Female, age 72, unknown 47.2
2219 Male, age 76, both hemispheres 46.2
2586 Male, age 75, left hemisphere 43.2
2666 Male, age 74, left hemisphere 39.7
1827 Male, age 72, unknown 39.1
Dorsal raphe nucleus
nTPM: 41.2
2750 Male, age 76, both hemispheres 63.7
2016 Female, age 72, unknown 40.5
1828 Male, age 53, unknown 39.1
2047 Male, age 72, unknown 32.4
2298 Female, age 72, unknown 30.6
Inferior colliculus
nTPM: 38.1
1890 Male, age 53, unknown 40.2
1848 Female, age 42, unknown 38.1
2849 Male, age 72, unknown 37.2
2097 Female, age 72, unknown 37.0
Median raphe nucleus
nTPM: 38.3
2220 Male, age 76, midline 38.3
Pedunculopontine tegmental nucleus
nTPM: 45.4
2334 Male, age 80, both hemispheres 48.2
1921 Female, age 85, both hemispheres 45.6
2338 Male, age 61, both hemispheres 42.3
Periaquaductal grey, anterior
nTPM: 33.7
1947 Male, age 18, unknown 34.2
2502 Female, age 75, unknown 33.5
1795 Male, age 51, unknown 33.4
Periaquaductal grey, dorsal
nTPM: 32.3
2464 Female, age 72, unknown 40.9
1831 Male, age 72, unknown 33.1
1840 Male, age 53, unknown 28.5
2850 Male, age 76, both hemispheres 26.9
Periaquaductal grey, lateral
nTPM: 34.4
2272 Male, age 74, both hemispheres 40.6
2053 Male, age 18, unknown 34.8
2140 Male, age 76, both hemispheres 27.7
Pretectal area
nTPM: 37.8
2316 Male, age 76, right hemisphere 47.4
1815 Male, age 53, unknown 44.1
1817 Female, age 42, unknown 41.7
2007 Male, age 72, unknown 41.7
2407 Male, age 75, both hemispheres 40.4
2273 Male, age 74, both hemispheres 38.0
2825 Male, age 18, unknown 36.7
2224 Female, age 72, unknown 34.0
1944 Female, age 72, unknown 32.1
2667 Female, age 75, unknown 30.2
1816 Male, age 51, unknown 30.0
Red nucleus
nTPM: 59.1
1904 Male, age 53, unknown 65.7
2785 Male, age 18, unknown 65.5
1865 Male, age 51, unknown 64.4
2823 Male, age 76, right hemisphere 63.4
2769 Male, age 72, unknown 61.9
2227 Male, age 72, unknown 60.6
1821 Female, age 72, unknown 59.9
2503 Female, age 72, unknown 59.7
2588 Male, age 74, left hemisphere 57.3
2725 Female, age 75, unknown 52.8
1954 Female, age 42, unknown 52.1
2584 Male, age 75, left hemisphere 45.3
Substantia nigra
nTPM: 39.8
2583 Male, age 75, right hemisphere 50.7
2590 Female, age 75, unknown 48.5
2409 Female, age 72, unknown 43.3
1851 Male, age 51, unknown 42.9
1889 Female, age 72, unknown 42.7
2241 Male, age 72, unknown 36.1
1941 Male, age 53, unknown 35.2
2699 Male, age 18, unknown 35.0
1916 Female, age 42, unknown 33.5
2665 Male, age 74, both hemispheres 30.5
Superior colliculus
nTPM: 44.5
1995 Male, age 72, unknown 57.6
1913 Female, age 42, unknown 57.5
2668 Female, age 75, unknown 49.2
1895 Male, age 76, right hemisphere 47.8
2587 Male, age 74, left hemisphere 47.8
1839 Male, age 51, unknown 44.5
1796 Male, age 53, unknown 40.2
2261 Male, age 18, unknown 36.6
2087 Female, age 72, unknown 32.7
2664 Male, age 75, both hemispheres 31.3
Ventral tegmental area
nTPM: 45.5
2223 Female, age 72, unknown 58.2
2410 Female, age 72, unknown 53.5
1942 Male, age 51, unknown 42.2
2218 Male, age 76, both hemispheres 40.8
2021 Male, age 53, unknown 40.3
1915 Female, age 42, unknown 38.3

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 63.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 63.4
Samples: 139

Max nTPM: 267.7
Min nTPM: 10.4
Std nTPM: 38.2
Median nTPM: 55.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 267.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 209.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 170.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 167.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 159.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 148.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 143.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 127.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 124.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 119.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 117.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 114.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 110.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 109.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 108.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 107.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 105.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 104.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 101.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 97.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 95.3
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 92.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 89.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 87.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 87.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 86.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 86.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 82.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 81.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 81.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 81.0
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 77.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 77.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 76.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 75.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 75.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 75.0
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 75.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 74.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 73.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 73.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 72.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 72.8
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 70.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 70.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 68.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 68.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 67.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 66.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 65.8
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 65.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 64.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 64.9
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 64.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 64.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 62.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 62.2
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 60.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 59.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 58.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 58.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 58.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 57.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 57.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 57.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 57.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 56.8
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 56.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 56.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 55.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 55.3
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 54.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 54.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 53.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 52.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 51.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 51.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 51.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 51.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 51.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 51.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 51.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 50.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 49.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 49.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 48.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 48.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 47.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 47.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 46.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 46.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 46.2
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 46.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 43.2
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 43.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 42.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 42.3
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 42.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 41.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 40.5
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 39.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 39.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 39.4
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 38.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 37.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 37.3
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 37.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 37.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 36.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 35.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 34.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 33.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 32.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 31.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 31.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 31.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 31.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 31.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 30.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 29.9
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 29.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 29.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 28.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 27.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 26.6
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 26.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 25.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 25.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 23.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 23.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 23.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 22.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 21.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 19.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 18.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 17.0
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 13.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 13.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 10.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 91.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 91.5
FF:10158-103A5 76 years, female 91.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 33.3
Pig sample Sample description nTPM
Midbrain
nTPM: 29.0
Samples: 4

Max nTPM: 36.9
Min nTPM: 21.3
Sample A Female 32.2
Sample B Female 36.9
Sample C Male 21.3
Sample D Male 25.5
Periaqueductal gray
nTPM: 27.1
Samples: 3

Max nTPM: 31.7
Min nTPM: 21.3
Sample B Female 31.7
Sample C Male 21.3
Sample D Male 28.2
Substantia nigra
nTPM: 33.3
Samples: 4

Max nTPM: 46.3
Min nTPM: 22.0
Sample A Female 38.6
Sample B Female 22.0
Sample C Male 26.1
Sample D Male 46.3
Superior colliculi
nTPM: 24.2
Samples: 4

Max nTPM: 32.3
Min nTPM: 11.4
Sample A Female 29.2
Sample B Female 11.4
Sample C Male 24.0
Sample D Male 32.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 35.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 35.6
Samples: 4

Max nTPM: 36.7
Min nTPM: 34.2
Sample A Male 35.7
Sample B Male 34.2
Sample C Female 36.7
Sample D Female 35.8

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 10.9
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 10.9
70565891 Antisense, RP_050628_01_F02, Mouse strain C57BL/6J (56 days, male) 10.9

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