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ATP6V0C
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  • ATP6V0C
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:139.7 nTPM
HPA:139.7 nTPM
GTEx:331.1 nTPM
FANTOM5:520.7 Scaled Tags Per Million
Pig:395.6 nTPM
Mouse:781.9 nTPM
Allen mouse:21.6 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 139.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 62.7
2666 Male, age 74, left hemisphere 107.3
1827 Male, age 72, unknown 93.1
2219 Male, age 76, both hemispheres 82.1
2586 Male, age 75, left hemisphere 65.5
2828 Female, age 72, unknown 64.2
1870 Female, age 42, unknown 60.7
2411 Female, age 72, unknown 55.3
1833 Male, age 53, unknown 39.8
2019 Male, age 18, unknown 34.6
1830 Male, age 51, unknown 24.7
Dorsal raphe nucleus
nTPM: 61.5
2298 Female, age 72, unknown 102.7
2750 Male, age 76, both hemispheres 70.5
2047 Male, age 72, unknown 70.4
1828 Male, age 53, unknown 64.1
2016 Female, age 72, unknown 0.0
Inferior colliculus
nTPM: 62.1
2097 Female, age 72, unknown 86.6
2849 Male, age 72, unknown 66.5
1848 Female, age 42, unknown 52.4
1890 Male, age 53, unknown 43.0
Median raphe nucleus
nTPM: 139.7
2220 Male, age 76, midline 139.7
Pedunculopontine tegmental nucleus
nTPM: 85.5
2334 Male, age 80, both hemispheres 102.2
1921 Female, age 85, both hemispheres 86.4
2338 Male, age 61, both hemispheres 67.7
Periaquaductal grey, anterior
nTPM: 92.4
1795 Male, age 51, unknown 126.0
1947 Male, age 18, unknown 102.4
2502 Female, age 75, unknown 48.8
Periaquaductal grey, dorsal
nTPM: 49.6
2850 Male, age 76, both hemispheres 66.2
1831 Male, age 72, unknown 64.0
1840 Male, age 53, unknown 38.9
2464 Female, age 72, unknown 29.1
Periaquaductal grey, lateral
nTPM: 39.1
2272 Male, age 74, both hemispheres 55.2
2053 Male, age 18, unknown 38.6
2140 Male, age 76, both hemispheres 23.6
Pretectal area
nTPM: 93.8
1816 Male, age 51, unknown 164.8
1817 Female, age 42, unknown 158.3
1944 Female, age 72, unknown 142.3
2007 Male, age 72, unknown 139.6
1815 Male, age 53, unknown 115.1
2667 Female, age 75, unknown 105.1
2224 Female, age 72, unknown 88.3
2825 Male, age 18, unknown 66.4
2273 Male, age 74, both hemispheres 29.0
2407 Male, age 75, both hemispheres 13.6
2316 Male, age 76, right hemisphere 8.8
Red nucleus
nTPM: 44.9
2584 Male, age 75, left hemisphere 70.2
2725 Female, age 75, unknown 67.8
2785 Male, age 18, unknown 67.4
1821 Female, age 72, unknown 60.5
2503 Female, age 72, unknown 42.8
1954 Female, age 42, unknown 42.0
2769 Male, age 72, unknown 37.8
2227 Male, age 72, unknown 37.3
2823 Male, age 76, right hemisphere 34.8
1904 Male, age 53, unknown 32.3
1865 Male, age 51, unknown 26.5
2588 Male, age 74, left hemisphere 19.7
Substantia nigra
nTPM: 82.6
1916 Female, age 42, unknown 151.9
1941 Male, age 53, unknown 122.9
1889 Female, age 72, unknown 121.6
1851 Male, age 51, unknown 96.2
2665 Male, age 74, both hemispheres 95.3
2583 Male, age 75, right hemisphere 72.7
2699 Male, age 18, unknown 64.2
2241 Male, age 72, unknown 34.3
2409 Female, age 72, unknown 33.6
2590 Female, age 75, unknown 33.3
Superior colliculus
nTPM: 67.4
1796 Male, age 53, unknown 119.3
2668 Female, age 75, unknown 117.8
2087 Female, age 72, unknown 100.3
2261 Male, age 18, unknown 93.2
2587 Male, age 74, left hemisphere 60.8
1913 Female, age 42, unknown 47.4
1839 Male, age 51, unknown 46.9
1895 Male, age 76, right hemisphere 44.9
1995 Male, age 72, unknown 24.6
2664 Male, age 75, both hemispheres 18.9
Ventral tegmental area
nTPM: 88.4
2218 Male, age 76, both hemispheres 144.8
1915 Female, age 42, unknown 111.7
2410 Female, age 72, unknown 95.7
2223 Female, age 72, unknown 80.7
1942 Male, age 51, unknown 59.8
2021 Male, age 53, unknown 38.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 331.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 331.1
Samples: 139

Max nTPM: 788.8
Min nTPM: 117.2
Std nTPM: 143.2
Median nTPM: 289.2
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 788.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 766.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 759.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 753.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 725.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 672.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 625.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 620.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 610.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 596.1
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 565.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 560.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 557.6
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 543.5
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 526.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 514.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 509.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 502.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 490.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 479.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 471.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 466.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 466.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 465.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 453.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 452.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 443.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 436.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 430.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 425.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 409.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 408.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 407.1
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 395.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 394.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 393.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 387.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 385.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 383.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 381.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 381.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 381.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 380.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 376.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 370.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 367.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 366.4
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 362.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 361.4
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 354.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 348.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 341.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 337.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 329.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 328.5
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 325.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 317.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 312.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 309.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 305.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 304.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 300.5
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 298.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 298.2
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 297.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 296.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 293.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 289.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 289.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 289.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 287.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 282.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 280.7
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 277.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 276.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 276.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 275.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 270.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 269.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 267.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 267.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 267.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 265.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 262.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 262.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 262.2
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 258.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 258.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 255.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 251.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 250.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 249.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 248.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 248.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 247.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 244.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 241.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 241.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 239.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 234.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 233.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 233.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 232.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 229.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 228.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 228.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 227.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 225.9
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 225.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 221.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 219.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 217.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 216.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 215.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 212.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 211.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 211.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 210.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 208.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 208.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 207.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 203.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 202.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 200.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 194.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 188.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 183.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 180.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 177.0
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 173.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 172.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 170.7
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 168.7
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 160.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 148.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 145.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 139.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 119.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 117.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 520.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 520.7
FF:10158-103A5 76 years, female 520.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 395.6
Pig sample Sample description nTPM
Midbrain
nTPM: 375.5
Samples: 4

Max nTPM: 532.6
Min nTPM: 290.7
Sample A Female 300.2
Sample B Female 290.7
Sample C Male 532.6
Sample D Male 378.3
Periaqueductal gray
nTPM: 288.6
Samples: 3

Max nTPM: 370.5
Min nTPM: 244.2
Sample B Female 251.2
Sample C Male 370.5
Sample D Male 244.2
Substantia nigra
nTPM: 353.7
Samples: 4

Max nTPM: 479.8
Min nTPM: 208.8
Sample A Female 466.9
Sample B Female 259.3
Sample C Male 479.8
Sample D Male 208.8
Superior colliculi
nTPM: 395.6
Samples: 4

Max nTPM: 473.5
Min nTPM: 269.8
Sample A Female 457.7
Sample B Female 269.8
Sample C Male 473.5
Sample D Male 381.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 781.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 781.9
Samples: 4

Max nTPM: 853.0
Min nTPM: 729.9
Sample A Male 853.0
Sample B Male 749.2
Sample C Female 729.9
Sample D Female 795.5

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 21.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 21.6
74881559 Antisense, RP_060315_04_C11, Mouse strain C57BL/6J (56 days, male) 21.6
69526976 Antisense, RP_050421_02_A08, Mouse strain C57BL/6J (56 days, male) 21.5

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