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TISSUE PRIMARY DATA MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN NASOPHARYNX ORAL MUCOSA
OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
ANTIBODIES
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VALIDATION
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:894.0 nTPM
HPA:894.0 nTPM
GTEx:741.3 nTPM
FANTOM5:1370.0 Scaled Tags Per Million
Pig:685.0 nTPM
Mouse:1056.7 nTPM
Allen mouse:18.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 894.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 832.7
2666 Male, age 74, left hemisphere 1067.5
1827 Male, age 72, unknown 888.6
2019 Male, age 18, unknown 880.8
2586 Male, age 75, left hemisphere 852.0
2828 Female, age 72, unknown 831.6
2411 Female, age 72, unknown 829.2
1870 Female, age 42, unknown 826.5
1833 Male, age 53, unknown 759.0
1830 Male, age 51, unknown 755.8
2219 Male, age 76, both hemispheres 636.0
Dorsal raphe nucleus
nTPM: 882.9
2298 Female, age 72, unknown 1053.0
2016 Female, age 72, unknown 892.7
1828 Male, age 53, unknown 875.8
2047 Male, age 72, unknown 851.3
2750 Male, age 76, both hemispheres 741.6
Inferior colliculus
nTPM: 803.3
2097 Female, age 72, unknown 887.9
1848 Female, age 42, unknown 796.7
1890 Male, age 53, unknown 777.7
2849 Male, age 72, unknown 750.7
Median raphe nucleus
nTPM: 761.0
2220 Male, age 76, midline 761.0
Pedunculopontine tegmental nucleus
nTPM: 800.3
2338 Male, age 61, both hemispheres 897.0
1921 Female, age 85, both hemispheres 759.0
2334 Male, age 80, both hemispheres 744.8
Periaquaductal grey, anterior
nTPM: 863.3
1947 Male, age 18, unknown 933.9
1795 Male, age 51, unknown 858.4
2502 Female, age 75, unknown 797.4
Periaquaductal grey, dorsal
nTPM: 832.6
1840 Male, age 53, unknown 892.8
2850 Male, age 76, both hemispheres 851.9
1831 Male, age 72, unknown 836.8
2464 Female, age 72, unknown 749.0
Periaquaductal grey, lateral
nTPM: 872.4
2272 Male, age 74, both hemispheres 961.0
2140 Male, age 76, both hemispheres 847.5
2053 Male, age 18, unknown 808.7
Pretectal area
nTPM: 894.0
2273 Male, age 74, both hemispheres 1089.4
1817 Female, age 42, unknown 961.5
1944 Female, age 72, unknown 961.4
1816 Male, age 51, unknown 928.1
2007 Male, age 72, unknown 917.6
2667 Female, age 75, unknown 913.1
2224 Female, age 72, unknown 892.9
1815 Male, age 53, unknown 889.0
2825 Male, age 18, unknown 803.1
2407 Male, age 75, both hemispheres 746.9
2316 Male, age 76, right hemisphere 731.0
Red nucleus
nTPM: 794.5
1821 Female, age 72, unknown 913.1
2725 Female, age 75, unknown 901.2
2785 Male, age 18, unknown 829.1
2503 Female, age 72, unknown 825.3
1954 Female, age 42, unknown 808.4
1865 Male, age 51, unknown 787.1
1904 Male, age 53, unknown 778.5
2769 Male, age 72, unknown 765.1
2584 Male, age 75, left hemisphere 763.5
2227 Male, age 72, unknown 750.6
2823 Male, age 76, right hemisphere 719.2
2588 Male, age 74, left hemisphere 693.3
Substantia nigra
nTPM: 888.3
1916 Female, age 42, unknown 1089.0
1851 Male, age 51, unknown 998.9
1889 Female, age 72, unknown 905.1
1941 Male, age 53, unknown 889.2
2583 Male, age 75, right hemisphere 885.3
2241 Male, age 72, unknown 862.7
2590 Female, age 75, unknown 859.7
2409 Female, age 72, unknown 838.0
2699 Male, age 18, unknown 833.2
2665 Male, age 74, both hemispheres 721.7
Superior colliculus
nTPM: 828.6
1796 Male, age 53, unknown 911.4
1995 Male, age 72, unknown 903.1
2087 Female, age 72, unknown 879.7
2261 Male, age 18, unknown 854.2
1913 Female, age 42, unknown 829.1
2587 Male, age 74, left hemisphere 828.9
1839 Male, age 51, unknown 784.7
2668 Female, age 75, unknown 781.4
2664 Male, age 75, both hemispheres 762.5
1895 Male, age 76, right hemisphere 751.6
Ventral tegmental area
nTPM: 872.8
1915 Female, age 42, unknown 1030.7
2410 Female, age 72, unknown 929.7
1942 Male, age 51, unknown 853.5
2021 Male, age 53, unknown 825.5
2223 Female, age 72, unknown 808.1
2218 Male, age 76, both hemispheres 789.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 741.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 741.3
Samples: 139

Max nTPM: 1495.1
Min nTPM: 397.2
Std nTPM: 209.6
Median nTPM: 718.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1495.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1336.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1282.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 1262.1
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1206.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1153.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1079.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1076.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 1076.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1067.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1049.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1036.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1016.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1000.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 999.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 993.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 985.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 984.5
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 970.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 947.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 946.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 943.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 933.5
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 927.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 917.4
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 917.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 915.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 914.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 910.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 908.5
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 906.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 898.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 898.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 871.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 867.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 865.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 862.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 859.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 855.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 852.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 847.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 834.8
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 832.4
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 830.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 822.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 820.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 819.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 814.9
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 812.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 808.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 807.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 804.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 792.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 791.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 789.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 783.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 775.9
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 773.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 761.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 758.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 757.6
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 754.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 753.2
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 746.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 732.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 727.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 718.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 718.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 718.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 718.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 717.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 716.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 711.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 704.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 704.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 696.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 692.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 688.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 675.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 673.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 671.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 670.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 666.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 665.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 659.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 656.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 653.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 651.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 650.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 648.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 647.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 646.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 635.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 628.6
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 626.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 625.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 623.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 617.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 615.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 606.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 604.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 598.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 593.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 587.1
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 587.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 581.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 572.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 570.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 563.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 563.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 559.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 557.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 544.1
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 540.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 536.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 534.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 532.1
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 529.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 525.9
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 525.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 513.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 511.5
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 497.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 489.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 483.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 472.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 465.7
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 455.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 453.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 448.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 443.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 438.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 435.9
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 419.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 413.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 413.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 409.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 401.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 397.2
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 1370.0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 1370.0
FF:10158-103A5 76 years, female 1370.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 685.0
Pig sample Sample description nTPM
Midbrain
nTPM: 685.0
Samples: 4

Max nTPM: 1157.1
Min nTPM: 443.7
Sample A Female 1157.1
Sample B Female 493.7
Sample C Male 645.5
Sample D Male 443.7
Periaqueductal gray
nTPM: 625.4
Samples: 3

Max nTPM: 756.1
Min nTPM: 545.5
Sample B Female 574.5
Sample C Male 756.1
Sample D Male 545.5
Substantia nigra
nTPM: 663.2
Samples: 4

Max nTPM: 811.3
Min nTPM: 544.6
Sample A Female 811.3
Sample B Female 544.6
Sample C Male 712.5
Sample D Male 584.3
Superior colliculi
nTPM: 632.1
Samples: 4

Max nTPM: 681.0
Min nTPM: 560.5
Sample A Female 681.0
Sample B Female 627.3
Sample C Male 659.7
Sample D Male 560.5

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 1056.7
Mouse sample Sample description nTPM
Midbrain
nTPM: 1056.7
Samples: 4

Max nTPM: 1075.2
Min nTPM: 1045.6
Sample A Male 1051.4
Sample B Male 1045.6
Sample C Female 1054.7
Sample D Female 1075.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 18.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 18.1
70919346 Antisense, RP_050713_01_B06, Mouse strain C57BL/6J (56 days, male) 22.0
846 Antisense, RP_Baylor_102983, Mouse strain C57BL/6J (56 days, male) 14.2
847 Antisense, RP_Baylor_102983, Mouse strain C57BL/6J (56 days, male) 12.7

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