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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:367.7 nTPM
HPA:367.7 nTPM
GTEx:517.6 nTPM
FANTOM5:34.2 Scaled Tags Per Million
Pig:500.9 nTPM
Mouse:728.6 nTPM
Allen mouse:9.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 367.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 354.4
1870 Female, age 42, unknown 368.9
2666 Male, age 74, left hemisphere 365.7
2411 Female, age 72, unknown 361.2
1833 Male, age 53, unknown 354.7
2219 Male, age 76, both hemispheres 354.3
1827 Male, age 72, unknown 352.0
1830 Male, age 51, unknown 351.6
2828 Female, age 72, unknown 349.2
2019 Male, age 18, unknown 345.3
2586 Male, age 75, left hemisphere 341.7
Dorsal raphe nucleus
nTPM: 354.3
2298 Female, age 72, unknown 359.4
2750 Male, age 76, both hemispheres 359.1
2016 Female, age 72, unknown 358.7
1828 Male, age 53, unknown 348.2
2047 Male, age 72, unknown 346.3
Inferior colliculus
nTPM: 358.5
2849 Male, age 72, unknown 361.8
1848 Female, age 42, unknown 359.7
1890 Male, age 53, unknown 358.2
2097 Female, age 72, unknown 354.4
Median raphe nucleus
nTPM: 358.8
2220 Male, age 76, midline 358.8
Pedunculopontine tegmental nucleus
nTPM: 367.7
2338 Male, age 61, both hemispheres 386.4
2334 Male, age 80, both hemispheres 370.9
1921 Female, age 85, both hemispheres 345.8
Periaquaductal grey, anterior
nTPM: 354.1
2502 Female, age 75, unknown 362.5
1947 Male, age 18, unknown 350.8
1795 Male, age 51, unknown 348.9
Periaquaductal grey, dorsal
nTPM: 357.4
1840 Male, age 53, unknown 368.3
2850 Male, age 76, both hemispheres 357.2
2464 Female, age 72, unknown 352.7
1831 Male, age 72, unknown 351.2
Periaquaductal grey, lateral
nTPM: 354.4
2140 Male, age 76, both hemispheres 357.7
2053 Male, age 18, unknown 356.8
2272 Male, age 74, both hemispheres 348.7
Pretectal area
nTPM: 349.8
2316 Male, age 76, right hemisphere 360.8
2224 Female, age 72, unknown 360.0
2825 Male, age 18, unknown 358.6
1815 Male, age 53, unknown 351.3
1817 Female, age 42, unknown 351.3
2007 Male, age 72, unknown 346.2
2667 Female, age 75, unknown 346.1
1816 Male, age 51, unknown 345.2
1944 Female, age 72, unknown 343.5
2273 Male, age 74, both hemispheres 342.5
2407 Male, age 75, both hemispheres 342.1
Red nucleus
nTPM: 358.4
2503 Female, age 72, unknown 379.8
1821 Female, age 72, unknown 364.7
1865 Male, age 51, unknown 362.9
2227 Male, age 72, unknown 360.3
2725 Female, age 75, unknown 358.4
2769 Male, age 72, unknown 357.4
1904 Male, age 53, unknown 356.7
1954 Female, age 42, unknown 355.6
2588 Male, age 74, left hemisphere 354.8
2823 Male, age 76, right hemisphere 351.3
2785 Male, age 18, unknown 349.9
2584 Male, age 75, left hemisphere 349.6
Substantia nigra
nTPM: 356.8
2699 Male, age 18, unknown 370.2
2241 Male, age 72, unknown 368.7
1851 Male, age 51, unknown 367.1
2665 Male, age 74, both hemispheres 364.7
2409 Female, age 72, unknown 360.3
2590 Female, age 75, unknown 355.5
1916 Female, age 42, unknown 350.0
1889 Female, age 72, unknown 347.7
1941 Male, age 53, unknown 347.2
2583 Male, age 75, right hemisphere 336.7
Superior colliculus
nTPM: 354.9
2587 Male, age 74, left hemisphere 368.7
1913 Female, age 42, unknown 364.8
1839 Male, age 51, unknown 358.5
1995 Male, age 72, unknown 358.3
1796 Male, age 53, unknown 354.0
1895 Male, age 76, right hemisphere 351.3
2261 Male, age 18, unknown 351.0
2668 Female, age 75, unknown 350.0
2664 Male, age 75, both hemispheres 347.6
2087 Female, age 72, unknown 345.0
Ventral tegmental area
nTPM: 362.5
2223 Female, age 72, unknown 370.7
2021 Male, age 53, unknown 367.5
1915 Female, age 42, unknown 362.6
2410 Female, age 72, unknown 361.7
2218 Male, age 76, both hemispheres 356.6
1942 Male, age 51, unknown 355.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 517.6
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 517.6
Samples: 139

Max nTPM: 1758.3
Min nTPM: 218.8
Std nTPM: 202.3
Median nTPM: 486.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 1758.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 1025.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 1024.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 975.2
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 956.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 945.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 841.2
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 838.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 804.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 798.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 791.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 778.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 773.0
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 765.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 757.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 747.0
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 746.0
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 732.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 730.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 724.3
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 716.0
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 702.8
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 693.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 683.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 681.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 675.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 656.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 656.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 639.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 637.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 636.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 626.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 619.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 612.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 596.8
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 596.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 596.1
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 594.3
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 590.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 589.8
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 586.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 582.0
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 581.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 578.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 574.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 571.0
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 568.7
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 566.5
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 566.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 554.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 546.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 539.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 536.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 535.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 533.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 526.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 517.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 516.2
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 511.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 504.3
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 502.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 501.7
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 499.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 498.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 492.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 490.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 490.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 488.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 486.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 486.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 482.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 470.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 469.6
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 469.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 468.3
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 466.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 463.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 462.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 458.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 458.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 454.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 453.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 453.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 447.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 441.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 431.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 418.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 417.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 414.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 414.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 414.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 412.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 403.9
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 401.6
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 397.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 387.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 383.9
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 383.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 383.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 381.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 379.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 378.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 375.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 374.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 373.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 370.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 367.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 367.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 365.5
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 363.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 360.1
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 358.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 356.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 356.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 356.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 350.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 349.7
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 348.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 341.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 339.7
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 337.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 330.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 327.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 317.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 306.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 303.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 299.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 298.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 297.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 290.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 289.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 287.0
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 286.7
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 282.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 276.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 264.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 243.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 241.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 218.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 34.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 34.2
FF:10158-103A5 76 years, female 34.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 500.9
Pig sample Sample description nTPM
Midbrain
nTPM: 484.8
Samples: 4

Max nTPM: 691.8
Min nTPM: 354.9
Sample A Female 691.8
Sample B Female 525.3
Sample C Male 354.9
Sample D Male 367.1
Periaqueductal gray
nTPM: 409.0
Samples: 3

Max nTPM: 428.0
Min nTPM: 387.8
Sample B Female 411.3
Sample C Male 428.0
Sample D Male 387.8
Substantia nigra
nTPM: 500.9
Samples: 4

Max nTPM: 577.7
Min nTPM: 467.0
Sample A Female 577.7
Sample B Female 484.7
Sample C Male 467.0
Sample D Male 474.3
Superior colliculi
nTPM: 485.8
Samples: 4

Max nTPM: 549.3
Min nTPM: 425.9
Sample A Female 549.3
Sample B Female 510.4
Sample C Male 425.9
Sample D Male 457.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 728.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 728.6
Samples: 4

Max nTPM: 751.4
Min nTPM: 694.2
Sample A Male 751.4
Sample B Male 741.6
Sample C Female 727.1
Sample D Female 694.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 9.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 9.7
69873295 Antisense, RP_050510_04_H12, Mouse strain C57BL/6J (56 days, male) 9.7

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