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  • GDI1
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:312.7 nTPM
HPA:312.7 nTPM
GTEx:281.1 nTPM
FANTOM5:244.3 Scaled Tags Per Million
Pig:416.5 nTPM
Mouse:432.3 nTPM
Allen mouse:21.4 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 312.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 294.7
1827 Male, age 72, unknown 320.7
2666 Male, age 74, left hemisphere 312.7
2411 Female, age 72, unknown 303.3
1870 Female, age 42, unknown 297.8
2828 Female, age 72, unknown 293.0
2219 Male, age 76, both hemispheres 288.6
2586 Male, age 75, left hemisphere 287.3
2019 Male, age 18, unknown 286.0
1833 Male, age 53, unknown 285.5
1830 Male, age 51, unknown 271.8
Dorsal raphe nucleus
nTPM: 283.4
2298 Female, age 72, unknown 296.1
2750 Male, age 76, both hemispheres 294.4
2047 Male, age 72, unknown 293.4
1828 Male, age 53, unknown 279.1
2016 Female, age 72, unknown 254.0
Inferior colliculus
nTPM: 287.5
2849 Male, age 72, unknown 302.1
1848 Female, age 42, unknown 285.9
2097 Female, age 72, unknown 285.8
1890 Male, age 53, unknown 276.3
Median raphe nucleus
nTPM: 312.7
2220 Male, age 76, midline 312.7
Pedunculopontine tegmental nucleus
nTPM: 303.8
1921 Female, age 85, both hemispheres 308.9
2334 Male, age 80, both hemispheres 306.2
2338 Male, age 61, both hemispheres 296.3
Periaquaductal grey, anterior
nTPM: 285.4
1947 Male, age 18, unknown 298.5
1795 Male, age 51, unknown 291.9
2502 Female, age 75, unknown 265.9
Periaquaductal grey, dorsal
nTPM: 278.8
1840 Male, age 53, unknown 288.8
1831 Male, age 72, unknown 283.8
2850 Male, age 76, both hemispheres 283.3
2464 Female, age 72, unknown 259.4
Periaquaductal grey, lateral
nTPM: 268.5
2053 Male, age 18, unknown 279.3
2272 Male, age 74, both hemispheres 269.4
2140 Male, age 76, both hemispheres 256.9
Pretectal area
nTPM: 306.3
1817 Female, age 42, unknown 342.9
1816 Male, age 51, unknown 337.6
2007 Male, age 72, unknown 330.3
1944 Female, age 72, unknown 329.4
1815 Male, age 53, unknown 316.6
2667 Female, age 75, unknown 312.5
2407 Male, age 75, both hemispheres 296.5
2224 Female, age 72, unknown 293.4
2825 Male, age 18, unknown 285.6
2273 Male, age 74, both hemispheres 274.3
2316 Male, age 76, right hemisphere 250.3
Red nucleus
nTPM: 278.9
1821 Female, age 72, unknown 297.4
2584 Male, age 75, left hemisphere 290.9
2785 Male, age 18, unknown 290.6
2588 Male, age 74, left hemisphere 290.5
2725 Female, age 75, unknown 285.8
1865 Male, age 51, unknown 277.3
2503 Female, age 72, unknown 273.2
1954 Female, age 42, unknown 270.9
2769 Male, age 72, unknown 270.2
1904 Male, age 53, unknown 268.6
2823 Male, age 76, right hemisphere 268.4
2227 Male, age 72, unknown 263.5
Substantia nigra
nTPM: 289.3
1889 Female, age 72, unknown 320.2
1941 Male, age 53, unknown 315.6
1916 Female, age 42, unknown 314.0
1851 Male, age 51, unknown 295.8
2583 Male, age 75, right hemisphere 294.2
2665 Male, age 74, both hemispheres 279.0
2590 Female, age 75, unknown 278.6
2699 Male, age 18, unknown 273.9
2241 Male, age 72, unknown 263.8
2409 Female, age 72, unknown 257.7
Superior colliculus
nTPM: 289.8
2668 Female, age 75, unknown 305.3
1796 Male, age 53, unknown 301.1
2087 Female, age 72, unknown 297.8
1895 Male, age 76, right hemisphere 292.4
2587 Male, age 74, left hemisphere 292.0
2261 Male, age 18, unknown 291.8
1839 Male, age 51, unknown 285.1
1913 Female, age 42, unknown 283.7
2664 Male, age 75, both hemispheres 282.3
1995 Male, age 72, unknown 266.1
Ventral tegmental area
nTPM: 294.1
2218 Male, age 76, both hemispheres 310.4
2410 Female, age 72, unknown 302.0
1915 Female, age 42, unknown 301.4
2223 Female, age 72, unknown 301.0
1942 Male, age 51, unknown 279.6
2021 Male, age 53, unknown 270.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 281.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 281.1
Samples: 139

Max nTPM: 612.0
Min nTPM: 176.9
Std nTPM: 65.7
Median nTPM: 271.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 612.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 499.0
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 457.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 430.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 418.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 391.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 390.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 384.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 383.0
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 382.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 380.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 379.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 377.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 375.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 365.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 357.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 354.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 350.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 344.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 344.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 342.4
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 336.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 335.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 335.6
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 334.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 330.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 326.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 320.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 320.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 318.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 317.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 317.1
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 317.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 316.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 314.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 313.7
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 312.7
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 310.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 309.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 308.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 306.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 305.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 305.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 304.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 304.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 302.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 301.7
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 300.5
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 300.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 299.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 298.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 297.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 296.7
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 296.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 295.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 292.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 290.4
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 285.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 285.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 285.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 284.9
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 279.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 279.3
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 278.4
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 278.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 276.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 275.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 275.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 274.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 271.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 270.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 267.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 264.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 263.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 260.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 260.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 259.8
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 255.0
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 254.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 253.7
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 251.9
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 251.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 248.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 247.9
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 245.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 245.1
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 244.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 244.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 244.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 243.5
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 243.0
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 242.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 241.9
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 241.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 241.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 240.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 240.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 239.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 239.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 238.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 237.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 236.7
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 236.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 232.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 232.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 231.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 230.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 230.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 229.5
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 229.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 229.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 227.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 226.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 225.1
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 224.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 223.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 223.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 222.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 221.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 216.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 215.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 215.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 214.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 214.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 214.1
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 213.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 212.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 211.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 207.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 207.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 202.9
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 202.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 201.2
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 199.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 194.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 193.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 192.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 183.6
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 176.9
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 244.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 244.3
FF:10158-103A5 76 years, female 244.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 416.5
Pig sample Sample description nTPM
Midbrain
nTPM: 416.6
Samples: 4

Max nTPM: 535.4
Min nTPM: 273.5
Sample A Female 448.3
Sample B Female 273.5
Sample C Male 535.4
Sample D Male 409.1
Periaqueductal gray
nTPM: 286.2
Samples: 3

Max nTPM: 335.4
Min nTPM: 257.3
Sample B Female 257.3
Sample C Male 335.4
Sample D Male 265.9
Substantia nigra
nTPM: 330.2
Samples: 4

Max nTPM: 406.7
Min nTPM: 241.8
Sample A Female 406.7
Sample B Female 241.8
Sample C Male 393.3
Sample D Male 279.0
Superior colliculi
nTPM: 397.3
Samples: 4

Max nTPM: 482.1
Min nTPM: 258.0
Sample A Female 426.1
Sample B Female 258.0
Sample C Male 482.1
Sample D Male 423.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 432.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 432.4
Samples: 4

Max nTPM: 442.0
Min nTPM: 418.6
Sample A Male 418.6
Sample B Male 442.0
Sample C Female 439.1
Sample D Female 429.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 21.4
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 21.4
74357589 Antisense, RP_060117_01_A05, Mouse strain C57BL/6J (56 days, male) 21.4

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