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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:104.5 nTPM
HPA:104.5 nTPM
GTEx:134.4 nTPM
FANTOM5:86.2 Scaled Tags Per Million
Pig:46.2 nTPM
Mouse:38.6 nTPM
Allen mouse:0.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 104.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 63.5
2411 Female, age 72, unknown 85.2
2219 Male, age 76, both hemispheres 73.4
1833 Male, age 53, unknown 68.8
1870 Female, age 42, unknown 68.0
2586 Male, age 75, left hemisphere 65.3
1830 Male, age 51, unknown 63.7
2666 Male, age 74, left hemisphere 55.7
2828 Female, age 72, unknown 54.4
1827 Male, age 72, unknown 54.0
2019 Male, age 18, unknown 46.9
Dorsal raphe nucleus
nTPM: 93.5
2047 Male, age 72, unknown 125.5
2298 Female, age 72, unknown 108.6
2750 Male, age 76, both hemispheres 86.3
1828 Male, age 53, unknown 77.9
2016 Female, age 72, unknown 69.3
Inferior colliculus
nTPM: 58.8
2849 Male, age 72, unknown 61.8
2097 Female, age 72, unknown 60.3
1890 Male, age 53, unknown 60.1
1848 Female, age 42, unknown 53.0
Median raphe nucleus
nTPM: 98.2
2220 Male, age 76, midline 98.2
Pedunculopontine tegmental nucleus
nTPM: 83.8
2334 Male, age 80, both hemispheres 99.1
1921 Female, age 85, both hemispheres 88.2
2338 Male, age 61, both hemispheres 64.0
Periaquaductal grey, anterior
nTPM: 61.4
1947 Male, age 18, unknown 63.2
1795 Male, age 51, unknown 62.6
2502 Female, age 75, unknown 58.4
Periaquaductal grey, dorsal
nTPM: 65.3
1840 Male, age 53, unknown 73.2
2850 Male, age 76, both hemispheres 70.5
2464 Female, age 72, unknown 65.0
1831 Male, age 72, unknown 52.6
Periaquaductal grey, lateral
nTPM: 59.7
2053 Male, age 18, unknown 63.8
2140 Male, age 76, both hemispheres 59.9
2272 Male, age 74, both hemispheres 55.5
Pretectal area
nTPM: 54.6
2825 Male, age 18, unknown 85.5
2224 Female, age 72, unknown 83.8
2667 Female, age 75, unknown 53.8
2273 Male, age 74, both hemispheres 50.6
2407 Male, age 75, both hemispheres 50.5
2316 Male, age 76, right hemisphere 49.6
1944 Female, age 72, unknown 46.7
1815 Male, age 53, unknown 45.3
2007 Male, age 72, unknown 45.3
1817 Female, age 42, unknown 45.1
1816 Male, age 51, unknown 44.5
Red nucleus
nTPM: 59.6
2584 Male, age 75, left hemisphere 72.2
2227 Male, age 72, unknown 63.7
1821 Female, age 72, unknown 63.3
1904 Male, age 53, unknown 63.2
1954 Female, age 42, unknown 63.2
2769 Male, age 72, unknown 63.1
2725 Female, age 75, unknown 57.7
1865 Male, age 51, unknown 56.5
2503 Female, age 72, unknown 56.0
2588 Male, age 74, left hemisphere 55.2
2823 Male, age 76, right hemisphere 54.6
2785 Male, age 18, unknown 46.4
Substantia nigra
nTPM: 104.5
1916 Female, age 42, unknown 146.0
2699 Male, age 18, unknown 141.2
1851 Male, age 51, unknown 133.9
2241 Male, age 72, unknown 127.3
2665 Male, age 74, both hemispheres 99.0
2409 Female, age 72, unknown 98.0
1941 Male, age 53, unknown 84.3
2583 Male, age 75, right hemisphere 78.9
2590 Female, age 75, unknown 71.8
1889 Female, age 72, unknown 64.8
Superior colliculus
nTPM: 53.3
2668 Female, age 75, unknown 60.1
1839 Male, age 51, unknown 57.9
1796 Male, age 53, unknown 56.9
2587 Male, age 74, left hemisphere 55.2
1995 Male, age 72, unknown 54.0
2261 Male, age 18, unknown 50.9
1913 Female, age 42, unknown 50.3
2664 Male, age 75, both hemispheres 50.3
1895 Male, age 76, right hemisphere 49.9
2087 Female, age 72, unknown 47.5
Ventral tegmental area
nTPM: 94.7
1915 Female, age 42, unknown 118.7
2410 Female, age 72, unknown 103.3
2218 Male, age 76, both hemispheres 92.0
1942 Male, age 51, unknown 89.7
2021 Male, age 53, unknown 89.6
2223 Female, age 72, unknown 74.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 134.4
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 134.4
Samples: 139

Max nTPM: 807.8
Min nTPM: 18.1
Std nTPM: 106.5
Median nTPM: 106.0
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 807.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 510.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 462.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 393.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 381.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 354.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 332.8
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 297.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 297.0
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 296.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 286.1
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 284.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 275.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 256.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 240.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 236.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 228.3
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 226.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 226.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 219.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 214.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 209.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 206.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 206.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 204.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 203.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 201.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 200.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 194.6
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 191.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 185.8
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 183.6
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 183.1
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 176.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 170.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 164.5
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 162.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 158.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 157.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 155.9
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 154.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 154.3
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 151.8
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 147.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 147.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 146.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 145.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 144.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 144.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 139.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 135.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 133.7
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 129.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 125.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 125.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 125.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 123.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 121.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 120.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 118.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 114.7
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 114.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 112.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 112.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 111.8
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 111.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 108.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 108.3
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 107.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 106.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 104.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 104.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 102.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 101.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 99.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 99.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 98.4
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 94.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 94.1
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 92.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 92.4
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 91.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 91.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 90.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 90.4
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 88.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 88.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 88.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 87.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 85.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 85.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 82.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 80.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 77.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 75.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 75.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 75.1
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 74.8
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 74.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 73.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 72.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 71.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 70.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 68.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 67.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 65.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 65.5
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 63.4
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 61.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 61.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 59.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 58.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 57.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 54.1
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 54.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 53.5
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 51.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 51.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 51.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 49.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 46.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 46.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 46.1
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 45.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 42.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 38.3
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 38.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 37.6
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 35.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 34.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 29.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 29.4
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 27.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 27.7
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 22.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 20.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 19.3
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 18.6
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 18.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 86.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 86.2
FF:10158-103A5 76 years, female 86.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 46.2
Pig sample Sample description nTPM
Midbrain
nTPM: 23.7
Samples: 4

Max nTPM: 40.3
Min nTPM: 7.5
Sample A Female 8.6
Sample B Female 40.3
Sample C Male 7.5
Sample D Male 38.4
Periaqueductal gray
nTPM: 39.9
Samples: 3

Max nTPM: 66.9
Min nTPM: 26.4
Sample B Female 26.4
Sample C Male 66.9
Sample D Male 26.5
Substantia nigra
nTPM: 46.2
Samples: 4

Max nTPM: 71.1
Min nTPM: 6.8
Sample A Female 69.4
Sample B Female 37.5
Sample C Male 71.1
Sample D Male 6.8
Superior colliculi
nTPM: 16.2
Samples: 4

Max nTPM: 28.9
Min nTPM: 3.2
Sample A Female 28.9
Sample B Female 23.8
Sample C Male 3.2
Sample D Male 8.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 38.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 38.6
Samples: 4

Max nTPM: 43.7
Min nTPM: 29.6
Sample A Male 40.7
Sample B Male 40.5
Sample C Female 29.6
Sample D Female 43.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 0.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.7
75080750 Antisense, RP_060412_04_G11, Mouse strain C57BL/6J (56 days, male) 0.9
79762714 Antisense, RP_071204_04_D12, Mouse strain C57BL/6J (56 days, male) 0.6

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