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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:49.3 nTPM
HPA:49.3 nTPM
GTEx:122.1 nTPM
FANTOM5:57.8 Scaled Tags Per Million
Pig:100.6 nTPM
Mouse:181.3 nTPM
Allen mouse:11.7 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 49.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 46.5
2019 Male, age 18, unknown 54.6
2411 Female, age 72, unknown 48.3
2828 Female, age 72, unknown 47.8
1827 Male, age 72, unknown 47.7
2586 Male, age 75, left hemisphere 46.4
1870 Female, age 42, unknown 44.8
1833 Male, age 53, unknown 44.4
2219 Male, age 76, both hemispheres 44.4
2666 Male, age 74, left hemisphere 43.5
1830 Male, age 51, unknown 43.0
Dorsal raphe nucleus
nTPM: 48.1
2298 Female, age 72, unknown 53.6
1828 Male, age 53, unknown 50.0
2047 Male, age 72, unknown 46.8
2016 Female, age 72, unknown 45.3
2750 Male, age 76, both hemispheres 44.7
Inferior colliculus
nTPM: 48.0
2097 Female, age 72, unknown 53.0
1890 Male, age 53, unknown 49.0
1848 Female, age 42, unknown 46.8
2849 Male, age 72, unknown 43.1
Median raphe nucleus
nTPM: 43.2
2220 Male, age 76, midline 43.2
Pedunculopontine tegmental nucleus
nTPM: 46.0
1921 Female, age 85, both hemispheres 48.4
2334 Male, age 80, both hemispheres 45.7
2338 Male, age 61, both hemispheres 43.9
Periaquaductal grey, anterior
nTPM: 46.8
1795 Male, age 51, unknown 48.2
2502 Female, age 75, unknown 47.0
1947 Male, age 18, unknown 45.3
Periaquaductal grey, dorsal
nTPM: 44.0
2464 Female, age 72, unknown 44.9
1840 Male, age 53, unknown 44.8
1831 Male, age 72, unknown 43.3
2850 Male, age 76, both hemispheres 42.8
Periaquaductal grey, lateral
nTPM: 45.3
2272 Male, age 74, both hemispheres 49.4
2140 Male, age 76, both hemispheres 43.8
2053 Male, age 18, unknown 42.8
Pretectal area
nTPM: 49.3
1817 Female, age 42, unknown 56.3
2007 Male, age 72, unknown 55.0
1816 Male, age 51, unknown 53.2
2273 Male, age 74, both hemispheres 51.1
1815 Male, age 53, unknown 50.3
1944 Female, age 72, unknown 50.2
2667 Female, age 75, unknown 49.3
2224 Female, age 72, unknown 46.3
2316 Male, age 76, right hemisphere 44.5
2825 Male, age 18, unknown 43.3
2407 Male, age 75, both hemispheres 42.8
Red nucleus
nTPM: 48.2
2725 Female, age 75, unknown 52.0
1821 Female, age 72, unknown 51.9
2785 Male, age 18, unknown 51.9
2503 Female, age 72, unknown 51.4
2769 Male, age 72, unknown 48.6
2227 Male, age 72, unknown 47.9
2823 Male, age 76, right hemisphere 47.8
1954 Female, age 42, unknown 47.5
1865 Male, age 51, unknown 46.7
2588 Male, age 74, left hemisphere 46.1
1904 Male, age 53, unknown 45.7
2584 Male, age 75, left hemisphere 40.4
Substantia nigra
nTPM: 47.6
1916 Female, age 42, unknown 51.1
1889 Female, age 72, unknown 50.9
1851 Male, age 51, unknown 49.4
2241 Male, age 72, unknown 49.4
2409 Female, age 72, unknown 47.7
2665 Male, age 74, both hemispheres 47.4
1941 Male, age 53, unknown 47.1
2699 Male, age 18, unknown 45.1
2583 Male, age 75, right hemisphere 43.9
2590 Female, age 75, unknown 43.7
Superior colliculus
nTPM: 46.6
2087 Female, age 72, unknown 50.5
1796 Male, age 53, unknown 49.1
2261 Male, age 18, unknown 48.5
2587 Male, age 74, left hemisphere 48.4
1895 Male, age 76, right hemisphere 47.4
2668 Female, age 75, unknown 46.3
1839 Male, age 51, unknown 44.6
1995 Male, age 72, unknown 44.4
1913 Female, age 42, unknown 44.1
2664 Male, age 75, both hemispheres 42.8
Ventral tegmental area
nTPM: 46.7
2410 Female, age 72, unknown 51.3
1915 Female, age 42, unknown 48.5
1942 Male, age 51, unknown 46.6
2218 Male, age 76, both hemispheres 45.9
2223 Female, age 72, unknown 44.6
2021 Male, age 53, unknown 43.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 122.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 122.1
Samples: 139

Max nTPM: 201.8
Min nTPM: 48.5
Std nTPM: 32.5
Median nTPM: 117.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 201.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 193.8
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 193.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 193.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 189.0
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 188.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 185.4
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 180.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 178.1
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 175.2
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 174.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 173.9
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 172.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 172.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 168.2
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 167.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 165.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 164.1
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 163.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 159.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 157.0
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 157.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 156.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 155.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 154.4
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 152.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 152.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 151.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 150.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 150.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 145.9
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 145.7
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 145.6
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 145.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 144.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 143.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 142.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 140.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 140.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 139.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 138.7
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 137.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 137.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 136.7
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 136.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 136.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 135.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 134.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 133.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 133.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 132.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 131.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 130.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 129.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 128.7
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 127.7
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 127.3
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 127.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 126.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 126.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 125.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 125.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 119.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 119.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 119.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 119.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 118.8
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 118.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 117.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 117.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 117.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 117.0
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 116.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 116.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 116.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 116.0
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 115.8
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 115.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 114.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 113.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 112.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 111.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 110.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 109.7
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 109.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 107.7
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 107.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 106.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 105.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 105.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 104.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 103.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 103.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 102.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 102.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 100.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 100.4
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 100.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 100.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 100.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 99.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 99.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 98.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 97.6
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 96.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 95.9
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 95.4
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 94.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 93.6
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 93.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 92.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 92.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 92.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 91.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 91.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 90.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 90.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 90.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 90.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 89.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 89.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 89.3
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 89.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 86.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 84.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 82.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 81.0
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 80.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 79.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 78.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 76.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 75.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 75.5
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 73.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 71.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 64.6
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 62.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 58.0
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 48.5
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 57.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 57.8
FF:10158-103A5 76 years, female 57.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 100.6
Pig sample Sample description nTPM
Midbrain
nTPM: 82.6
Samples: 4

Max nTPM: 95.3
Min nTPM: 73.3
Sample A Female 80.9
Sample B Female 73.3
Sample C Male 95.3
Sample D Male 80.7
Periaqueductal gray
nTPM: 63.8
Samples: 3

Max nTPM: 71.0
Min nTPM: 56.5
Sample B Female 63.9
Sample C Male 71.0
Sample D Male 56.5
Substantia nigra
nTPM: 74.7
Samples: 4

Max nTPM: 104.6
Min nTPM: 57.9
Sample A Female 104.6
Sample B Female 57.9
Sample C Male 72.4
Sample D Male 64.0
Superior colliculi
nTPM: 100.6
Samples: 4

Max nTPM: 124.9
Min nTPM: 74.5
Sample A Female 122.3
Sample B Female 74.5
Sample C Male 124.9
Sample D Male 80.7

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 181.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 181.4
Samples: 4

Max nTPM: 192.6
Min nTPM: 167.7
Sample A Male 190.7
Sample B Male 174.4
Sample C Female 167.7
Sample D Female 192.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 11.7
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 11.7
67767465 Antisense, RP_040916_02_B04, Mouse strain C57BL/6J (56 days, male) 11.7

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