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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:70.8 nTPM
HPA:70.8 nTPM
GTEx:161.3 nTPM
FANTOM5:45.5 Scaled Tags Per Million
Pig:64.0 nTPM
Mouse:92.4 nTPM
Allen mouse:2.1 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 70.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 70.8
2586 Male, age 75, left hemisphere 87.2
2666 Male, age 74, left hemisphere 77.4
2828 Female, age 72, unknown 74.8
1827 Male, age 72, unknown 74.0
2411 Female, age 72, unknown 69.4
1830 Male, age 51, unknown 66.9
1833 Male, age 53, unknown 65.2
1870 Female, age 42, unknown 65.0
2019 Male, age 18, unknown 64.8
2219 Male, age 76, both hemispheres 63.6
Dorsal raphe nucleus
nTPM: 65.1
2750 Male, age 76, both hemispheres 66.8
2047 Male, age 72, unknown 66.4
1828 Male, age 53, unknown 65.5
2016 Female, age 72, unknown 64.3
2298 Female, age 72, unknown 62.6
Inferior colliculus
nTPM: 62.5
2849 Male, age 72, unknown 64.9
1848 Female, age 42, unknown 63.0
1890 Male, age 53, unknown 61.8
2097 Female, age 72, unknown 60.2
Median raphe nucleus
nTPM: 65.1
2220 Male, age 76, midline 65.1
Pedunculopontine tegmental nucleus
nTPM: 65.0
2334 Male, age 80, both hemispheres 68.7
1921 Female, age 85, both hemispheres 64.7
2338 Male, age 61, both hemispheres 61.4
Periaquaductal grey, anterior
nTPM: 68.3
1795 Male, age 51, unknown 70.1
1947 Male, age 18, unknown 68.2
2502 Female, age 75, unknown 66.6
Periaquaductal grey, dorsal
nTPM: 62.5
2464 Female, age 72, unknown 63.6
1840 Male, age 53, unknown 63.1
1831 Male, age 72, unknown 63.0
2850 Male, age 76, both hemispheres 60.4
Periaquaductal grey, lateral
nTPM: 60.3
2053 Male, age 18, unknown 63.8
2272 Male, age 74, both hemispheres 59.4
2140 Male, age 76, both hemispheres 57.8
Pretectal area
nTPM: 65.4
2007 Male, age 72, unknown 70.9
1817 Female, age 42, unknown 69.1
2825 Male, age 18, unknown 69.1
1815 Male, age 53, unknown 68.8
2407 Male, age 75, both hemispheres 67.5
1816 Male, age 51, unknown 67.1
2667 Female, age 75, unknown 64.6
1944 Female, age 72, unknown 64.5
2224 Female, age 72, unknown 61.0
2316 Male, age 76, right hemisphere 59.8
2273 Male, age 74, both hemispheres 57.3
Red nucleus
nTPM: 67.4
2584 Male, age 75, left hemisphere 76.7
2769 Male, age 72, unknown 69.3
2588 Male, age 74, left hemisphere 68.2
2227 Male, age 72, unknown 67.9
2785 Male, age 18, unknown 67.3
1821 Female, age 72, unknown 67.0
2725 Female, age 75, unknown 66.5
1954 Female, age 42, unknown 66.1
1865 Male, age 51, unknown 65.6
2823 Male, age 76, right hemisphere 65.1
1904 Male, age 53, unknown 64.8
2503 Female, age 72, unknown 64.7
Substantia nigra
nTPM: 68.8
2583 Male, age 75, right hemisphere 76.9
1916 Female, age 42, unknown 76.5
2665 Male, age 74, both hemispheres 76.0
1941 Male, age 53, unknown 70.6
1851 Male, age 51, unknown 70.0
2699 Male, age 18, unknown 68.2
1889 Female, age 72, unknown 65.6
2590 Female, age 75, unknown 65.5
2409 Female, age 72, unknown 60.8
2241 Male, age 72, unknown 57.8
Superior colliculus
nTPM: 66.8
2664 Male, age 75, both hemispheres 76.8
2668 Female, age 75, unknown 72.7
1796 Male, age 53, unknown 70.3
1839 Male, age 51, unknown 66.2
2587 Male, age 74, left hemisphere 65.2
2087 Female, age 72, unknown 64.7
1913 Female, age 42, unknown 64.5
2261 Male, age 18, unknown 64.0
1995 Male, age 72, unknown 62.7
1895 Male, age 76, right hemisphere 61.2
Ventral tegmental area
nTPM: 68.0
2218 Male, age 76, both hemispheres 70.7
1915 Female, age 42, unknown 70.1
2410 Female, age 72, unknown 68.0
1942 Male, age 51, unknown 67.7
2223 Female, age 72, unknown 66.1
2021 Male, age 53, unknown 65.6

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 161.3
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 161.3
Samples: 139

Max nTPM: 365.3
Min nTPM: 71.1
Std nTPM: 40.5
Median nTPM: 155.8
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 365.3
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 285.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 276.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 256.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 246.7
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 233.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 232.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 229.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 226.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 222.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 218.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 211.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 211.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 208.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 206.6
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 204.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 203.5
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 202.5
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 199.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 198.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 193.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 192.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 192.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 190.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 189.5
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 189.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 189.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 187.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 187.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 187.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 185.9
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 185.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 183.4
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 182.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 181.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 181.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 180.6
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 180.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 179.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 178.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 177.4
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 176.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 176.4
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 175.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 175.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 173.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 171.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 170.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 169.7
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 169.4
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 169.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 168.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 166.9
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 166.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 166.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 166.0
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 165.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 165.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 164.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 163.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 161.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 161.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 160.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 160.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 160.2
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 159.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 158.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 157.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 155.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 155.8
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 155.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 154.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 153.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 153.1
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 151.8
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 151.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 151.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 151.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 150.2
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 150.0
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 149.8
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 149.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 148.8
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 148.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 146.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 145.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 145.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 144.6
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 143.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 143.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 141.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 140.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 139.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 139.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 139.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 139.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 139.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 139.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 138.4
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 138.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 138.0
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 137.9
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 137.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 136.3
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 136.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 135.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 134.3
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 133.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 133.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 132.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 132.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 131.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 129.5
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 127.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 127.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 127.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 127.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 127.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 125.9
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 123.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 123.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 122.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 120.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 117.2
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 116.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 116.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 115.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 114.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 114.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 112.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 110.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 110.3
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 109.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 102.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 100.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 92.7
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 89.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 89.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 71.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 45.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 45.5
FF:10158-103A5 76 years, female 45.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 64.0
Pig sample Sample description nTPM
Midbrain
nTPM: 64.1
Samples: 4

Max nTPM: 74.4
Min nTPM: 52.5
Sample A Female 74.4
Sample B Female 52.5
Sample C Male 70.5
Sample D Male 58.8
Periaqueductal gray
nTPM: 49.1
Samples: 3

Max nTPM: 51.1
Min nTPM: 46.7
Sample B Female 51.1
Sample C Male 49.4
Sample D Male 46.7
Substantia nigra
nTPM: 60.1
Samples: 4

Max nTPM: 79.0
Min nTPM: 51.8
Sample A Female 79.0
Sample B Female 56.0
Sample C Male 53.5
Sample D Male 51.8
Superior colliculi
nTPM: 57.6
Samples: 4

Max nTPM: 75.3
Min nTPM: 48.2
Sample A Female 75.3
Sample B Female 48.2
Sample C Male 51.6
Sample D Male 55.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 92.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 92.4
Samples: 4

Max nTPM: 104.7
Min nTPM: 83.1
Sample A Male 104.7
Sample B Male 83.5
Sample C Female 83.1
Sample D Female 98.4

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 2.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.1
69528100 Antisense, RP_050421_03_B03, Mouse strain C57BL/6J (56 days, male) 2.1

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