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MT-ATP8
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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:85769.3 nTPM
HPA:85769.3 nTPM
GTEx:125879.0 nTPM
Pig:20302.7 nTPM
Mouse:7586.3 nTPM

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 85769.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 65467.4
2219 Male, age 76, both hemispheres 98801.0
1833 Male, age 53, unknown 68377.8
2666 Male, age 74, left hemisphere 66593.4
1830 Male, age 51, unknown 66358.3
2828 Female, age 72, unknown 63262.1
2586 Male, age 75, left hemisphere 62635.0
1870 Female, age 42, unknown 58462.6
1827 Male, age 72, unknown 58233.5
2019 Male, age 18, unknown 56342.8
2411 Female, age 72, unknown 55606.9
Dorsal raphe nucleus
nTPM: 55771.1
1828 Male, age 53, unknown 63100.9
2750 Male, age 76, both hemispheres 59111.0
2047 Male, age 72, unknown 53357.1
2016 Female, age 72, unknown 53255.7
2298 Female, age 72, unknown 50030.6
Inferior colliculus
nTPM: 62030.1
2849 Male, age 72, unknown 82358.5
1890 Male, age 53, unknown 57878.8
1848 Female, age 42, unknown 55431.4
2097 Female, age 72, unknown 52451.7
Median raphe nucleus
nTPM: 85769.3
2220 Male, age 76, midline 85769.3
Pedunculopontine tegmental nucleus
nTPM: 68352.7
2334 Male, age 80, both hemispheres 76959.4
2338 Male, age 61, both hemispheres 73384.2
1921 Female, age 85, both hemispheres 54714.6
Periaquaductal grey, anterior
nTPM: 57959.7
2502 Female, age 75, unknown 64347.2
1795 Male, age 51, unknown 55429.5
1947 Male, age 18, unknown 54102.4
Periaquaductal grey, dorsal
nTPM: 64248.3
2850 Male, age 76, both hemispheres 82849.4
2464 Female, age 72, unknown 62423.2
1831 Male, age 72, unknown 59256.5
1840 Male, age 53, unknown 52464.1
Periaquaductal grey, lateral
nTPM: 55558.7
2140 Male, age 76, both hemispheres 58601.2
2053 Male, age 18, unknown 54185.7
2272 Male, age 74, both hemispheres 53889.1
Pretectal area
nTPM: 60365.4
1815 Male, age 53, unknown 67815.3
1816 Male, age 51, unknown 67662.2
1817 Female, age 42, unknown 66370.7
2667 Female, age 75, unknown 64972.6
1944 Female, age 72, unknown 62732.2
2825 Male, age 18, unknown 62532.0
2007 Male, age 72, unknown 56779.8
2407 Male, age 75, both hemispheres 55860.6
2224 Female, age 72, unknown 55378.0
2273 Male, age 74, both hemispheres 52064.4
2316 Male, age 76, right hemisphere 51851.3
Red nucleus
nTPM: 61682.3
2503 Female, age 72, unknown 70345.7
1954 Female, age 42, unknown 65091.8
2823 Male, age 76, right hemisphere 64406.1
2227 Male, age 72, unknown 63119.3
2588 Male, age 74, left hemisphere 61359.6
2785 Male, age 18, unknown 61237.6
2769 Male, age 72, unknown 59905.3
2725 Female, age 75, unknown 59668.9
1865 Male, age 51, unknown 59465.4
1904 Male, age 53, unknown 59439.2
2584 Male, age 75, left hemisphere 59216.3
1821 Female, age 72, unknown 56932.8
Substantia nigra
nTPM: 63122.8
2699 Male, age 18, unknown 80550.2
2665 Male, age 74, both hemispheres 76025.6
1916 Female, age 42, unknown 65983.1
1941 Male, age 53, unknown 65918.5
2409 Female, age 72, unknown 61767.7
2241 Male, age 72, unknown 58753.5
2583 Male, age 75, right hemisphere 56313.2
1889 Female, age 72, unknown 55954.9
1851 Male, age 51, unknown 55400.9
2590 Female, age 75, unknown 54560.5
Superior colliculus
nTPM: 58614.4
2664 Male, age 75, both hemispheres 61677.6
2087 Female, age 72, unknown 61626.4
1839 Male, age 51, unknown 61324.1
1913 Female, age 42, unknown 60428.3
1995 Male, age 72, unknown 57639.0
2587 Male, age 74, left hemisphere 57575.0
1895 Male, age 76, right hemisphere 57317.0
2261 Male, age 18, unknown 57291.6
2668 Female, age 75, unknown 56381.2
1796 Male, age 53, unknown 54883.9
Ventral tegmental area
nTPM: 64941.9
2218 Male, age 76, both hemispheres 82946.0
2223 Female, age 72, unknown 71446.3
1942 Male, age 51, unknown 61328.4
1915 Female, age 42, unknown 58252.4
2021 Male, age 53, unknown 58054.7
2410 Female, age 72, unknown 57623.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 125879.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 125879.0
Samples: 139

Max nTPM: 446937.0
Min nTPM: 21082.0
Std nTPM: 83185.2
Median nTPM: 101775.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 446937.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 410072.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 405248.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 373563.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 349592.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 334526.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 329128.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 296816.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 293294.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 261202.2
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 257441.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 256801.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 250068.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 243740.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 234130.8
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 231334.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 220099.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 217070.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 213442.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 209231.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 208609.3
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 203388.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 199990.7
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 187711.5
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 186775.5
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 180120.2
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 179791.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 174596.8
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 172301.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 164057.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 161418.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 160874.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 160193.7
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 159699.2
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 158643.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 158083.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 156667.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 152740.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 152032.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 150011.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 145479.4
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 136498.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 132836.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 132098.1
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 130647.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 128596.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 125863.2
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 123763.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 122660.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 119210.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 117711.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 117180.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 116906.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 116077.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 114916.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 114264.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 113370.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 111383.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 108612.0
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 108298.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 108135.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 107890.5
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 107479.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 107074.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 106199.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 105884.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 105503.5
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 105247.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 101782.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 101775.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 100993.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 100395.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 99548.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 99446.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 99347.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 99096.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 95778.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 95570.7
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 95452.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 91391.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 90371.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 90196.9
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 87830.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 86676.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 85749.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 84762.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 84011.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 84000.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 83759.6
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 81156.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 81038.5
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 80656.8
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 79937.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 79534.7
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 79005.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 77899.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 77865.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 76647.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 76140.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 75862.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 75349.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 75209.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 74557.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 74270.3
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 74196.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 73186.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 72724.5
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 71916.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 70922.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 70337.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 68885.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 66069.8
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 65115.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 64028.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 62817.4
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 61055.2
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 60302.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 60070.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 59506.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 56942.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 55367.5
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 51970.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 49492.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 48697.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 48467.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 47635.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 46715.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 45285.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 44894.0
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 41227.6
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 40134.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 38959.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 36415.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 35426.1
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 34940.7
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 34099.5
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 22356.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 21628.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 21082.0
Show allShow less

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 20302.7
Pig sample Sample description nTPM
Midbrain
nTPM: 20302.7
Samples: 4

Max nTPM: 32750.2
Min nTPM: 9341.6
Sample A Female 17446.3
Sample B Female 32750.2
Sample C Male 21672.7
Sample D Male 9341.6
Periaqueductal gray
nTPM: 13859.0
Samples: 3

Max nTPM: 16161.2
Min nTPM: 9951.2
Sample B Female 15464.6
Sample C Male 16161.2
Sample D Male 9951.2
Substantia nigra
nTPM: 16911.1
Samples: 4

Max nTPM: 26066.8
Min nTPM: 7595.8
Sample A Female 26066.8
Sample B Female 15067.4
Sample C Male 18914.3
Sample D Male 7595.8
Superior colliculi
nTPM: 14535.8
Samples: 4

Max nTPM: 25215.6
Min nTPM: 1599.8
Sample A Female 25215.6
Sample B Female 1599.8
Sample C Male 17731.7
Sample D Male 13595.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 7586.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 7586.4
Samples: 4

Max nTPM: 10888.4
Min nTPM: 5023.9
Sample A Male 10888.4
Sample B Male 8540.4
Sample C Female 5892.7
Sample D Female 5023.9

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