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PCDHGC3
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BRAIN WHITE MATTER Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
WHITE MATTER - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:220.8 nTPM
HPA:220.8 nTPM
FANTOM5:282.1 Scaled Tags Per Million
Mouse:94.6 nTPM

WHITE MATTER - HPA Brain RNA-seq
Max nTPM 220.8
Sample id Sample description nTPM
Angular gyrus (white matter)
nTPM: 195.6
1920 Male, age 76, both hemispheres 195.6
Anterior funiculus (white matter)
nTPM: 202.9
2818 Female, age 79, both hemispheres 217.4
2819 Male, age 47, both hemispheres 207.9
2193 Male, age 75, both hemispheres 193.9
2734 Male, age 80, both hemispheres 192.3
Area striata (white matter)
nTPM: 188.9
2258 Female, age 91, left hemisphere 188.9
Cerebellar white matter
nTPM: 220.8
1837 Male, age 76, left hemisphere 267.7
1864 Male, age 80, left hemisphere 239.7
2773 Female, age 85, right hemisphere 224.8
2174 Male, age 61, right hemisphere 218.0
1931 Female, age 91, left hemisphere 204.2
2105 Male, age 74, right hemisphere 170.1
Corpus callosum, genu (white matter)
nTPM: 191.9
1887 Male, age 76, left hemisphere 208.2
1849 Female, age 91, right hemisphere 196.2
1934 Male, age 61, right hemisphere 187.9
1886 Female, age 67, right hemisphere 187.8
2771 Male, age 75, left hemisphere 186.6
1885 Female, age 94, left hemisphere 184.5
Corpus callosum, splenium (white matter)
nTPM: 189.5
1946 Male, age 76, left hemisphere 227.2
2104 Male, age 75, left hemisphere 181.9
2847 Female, age 67, right hemisphere 178.2
2238 Female, age 94, right hemisphere 170.8
Dorsal funiculus (white matter)
nTPM: 206.1
2064 Female, age 79, both hemispheres 237.5
2817 Male, age 47, both hemispheres 212.6
2812 Male, age 66, both hemispheres 205.3
2128 Male, age 75, both hemispheres 195.2
2810 Male, age 90, both hemispheres 179.8
Lateral funiculus (white matter)
nTPM: 196.6
2094 Female, age 79, both hemispheres 221.3
2192 Male, age 75, both hemispheres 194.0
2294 Male, age 66, both hemispheres 192.4
2099 Male, age 90, both hemispheres 178.7
Occipital cortex (white matter)
nTPM: 200.1
2259 Male, age 75, midline 205.6
2257 Female, age 67, both hemispheres 194.7
Parahippocampal cortex (white matter)
nTPM: 195.8
2157 Female, age 91, both hemispheres 195.8
Parieto-temporal junction (white matter)
nTPM: 181.0
2121 Male, age 76, left hemisphere 197.7
2774 Male, age 61, right hemisphere 191.1
2770 Female, age 91, right hemisphere 182.1
1999 Female, age 67, right hemisphere 175.4
2469 Male, age 75, right hemisphere 173.2
1935 Female, age 94, right hemisphere 166.7
Somatomor cortex, precentral gyrus (white matter)
nTPM: 202.5
2439 Male, age 75, right hemisphere 202.5
Somatosensory cortex, postcentral gyrus, ventral (white matter)
nTPM: 199.9
2623 Male, age 75, right hemisphere 199.9
Temporal white matter
nTPM: 191.3
1801 Male, age 76, left hemisphere 227.7
2524 Female, age 85, left hemisphere 185.9
2523 Female, age 94, left hemisphere 184.5
2736 Female, age 91, right hemisphere 180.8
2254 Male, age 75, right hemisphere 177.4

WHITE MATTER - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 282.1
FANTOM5 sample id Sample description Scaled Tags Per Million
Corpus callosum
Scaled Tags Per Million: 282.1
FF:10042-101F6 24-68 years, mixed 282.1

WHITE MATTER - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 94.6
Mouse sample Sample description nTPM
Corpus callosum
nTPM: 94.6
Samples: 3

Max nTPM: 103.4
Min nTPM: 86.0
Sample A Male 103.4
Sample B Male 86.0
Sample D Female 94.4

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.