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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
AND
VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:320.7 nTPM
HPA:320.7 nTPM
GTEx:344.0 nTPM
FANTOM5:139.2 Scaled Tags Per Million
Pig:0.0 nTPM
Mouse:137.0 nTPM
Allen mouse:4.6 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 320.7
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 305.8
2019 Male, age 18, unknown 323.0
2586 Male, age 75, left hemisphere 315.4
2666 Male, age 74, left hemisphere 314.5
1827 Male, age 72, unknown 306.0
2828 Female, age 72, unknown 306.0
1870 Female, age 42, unknown 304.5
2411 Female, age 72, unknown 304.4
1833 Male, age 53, unknown 296.0
2219 Male, age 76, both hemispheres 294.7
1830 Male, age 51, unknown 293.4
Dorsal raphe nucleus
nTPM: 314.3
2047 Male, age 72, unknown 329.1
2298 Female, age 72, unknown 320.8
1828 Male, age 53, unknown 315.4
2750 Male, age 76, both hemispheres 311.5
2016 Female, age 72, unknown 294.5
Inferior colliculus
nTPM: 303.0
1890 Male, age 53, unknown 313.4
2097 Female, age 72, unknown 310.7
1848 Female, age 42, unknown 296.2
2849 Male, age 72, unknown 291.9
Median raphe nucleus
nTPM: 313.4
2220 Male, age 76, midline 313.4
Pedunculopontine tegmental nucleus
nTPM: 316.6
2338 Male, age 61, both hemispheres 335.6
2334 Male, age 80, both hemispheres 313.5
1921 Female, age 85, both hemispheres 300.8
Periaquaductal grey, anterior
nTPM: 310.2
1947 Male, age 18, unknown 311.3
1795 Male, age 51, unknown 311.2
2502 Female, age 75, unknown 308.0
Periaquaductal grey, dorsal
nTPM: 294.9
2850 Male, age 76, both hemispheres 296.4
1831 Male, age 72, unknown 295.8
2464 Female, age 72, unknown 294.3
1840 Male, age 53, unknown 292.9
Periaquaductal grey, lateral
nTPM: 293.6
2272 Male, age 74, both hemispheres 300.3
2053 Male, age 18, unknown 291.8
2140 Male, age 76, both hemispheres 288.5
Pretectal area
nTPM: 306.5
2007 Male, age 72, unknown 323.3
1817 Female, age 42, unknown 322.7
1944 Female, age 72, unknown 321.4
1816 Male, age 51, unknown 320.7
1815 Male, age 53, unknown 309.4
2667 Female, age 75, unknown 305.1
2273 Male, age 74, both hemispheres 296.3
2407 Male, age 75, both hemispheres 294.2
2825 Male, age 18, unknown 294.0
2316 Male, age 76, right hemisphere 292.8
2224 Female, age 72, unknown 292.2
Red nucleus
nTPM: 311.3
1821 Female, age 72, unknown 326.5
2503 Female, age 72, unknown 324.6
2725 Female, age 75, unknown 319.8
2785 Male, age 18, unknown 314.7
1865 Male, age 51, unknown 313.0
2588 Male, age 74, left hemisphere 307.6
1904 Male, age 53, unknown 306.7
2769 Male, age 72, unknown 306.1
2227 Male, age 72, unknown 305.9
2823 Male, age 76, right hemisphere 304.5
2584 Male, age 75, left hemisphere 304.4
1954 Female, age 42, unknown 302.3
Substantia nigra
nTPM: 320.7
1916 Female, age 42, unknown 340.4
1851 Male, age 51, unknown 338.9
1889 Female, age 72, unknown 325.8
2665 Male, age 74, both hemispheres 322.8
1941 Male, age 53, unknown 322.7
2241 Male, age 72, unknown 318.9
2590 Female, age 75, unknown 312.1
2699 Male, age 18, unknown 311.6
2409 Female, age 72, unknown 308.4
2583 Male, age 75, right hemisphere 305.2
Superior colliculus
nTPM: 301.8
2087 Female, age 72, unknown 312.1
2587 Male, age 74, left hemisphere 310.1
1796 Male, age 53, unknown 309.2
2261 Male, age 18, unknown 302.6
2668 Female, age 75, unknown 302.5
2664 Male, age 75, both hemispheres 301.5
1913 Female, age 42, unknown 297.2
1895 Male, age 76, right hemisphere 295.7
1995 Male, age 72, unknown 294.1
1839 Male, age 51, unknown 293.2
Ventral tegmental area
nTPM: 311.7
1915 Female, age 42, unknown 326.1
2410 Female, age 72, unknown 316.8
2218 Male, age 76, both hemispheres 311.9
2223 Female, age 72, unknown 311.4
1942 Male, age 51, unknown 303.1
2021 Male, age 53, unknown 300.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 344.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 344.0
Samples: 139

Max nTPM: 686.6
Min nTPM: 178.4
Std nTPM: 85.1
Median nTPM: 333.0
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 686.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 646.1
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 631.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 547.7
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 529.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 509.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 495.9
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 492.5
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 486.3
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 478.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 462.0
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 456.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 455.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 445.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 443.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 441.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 438.5
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 430.8
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 429.6
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 422.9
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 422.4
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 421.6
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 417.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 414.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 411.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 409.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 406.9
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 401.2
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 396.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 394.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 392.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 390.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 385.7
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 385.2
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 384.7
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 383.8
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 376.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 372.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 369.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 369.3
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 368.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 367.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 365.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 364.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 361.5
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 359.0
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 358.0
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 356.1
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 355.4
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 354.9
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 354.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 354.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 353.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 352.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 352.4
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 350.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 350.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 345.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 343.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 339.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 338.6
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 338.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 338.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 337.7
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 337.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 336.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 336.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 335.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 334.9
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 333.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 332.2
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 331.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 331.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 331.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 331.2
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 329.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 328.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 326.8
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 326.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 325.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 324.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 324.4
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 324.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 323.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 322.8
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 320.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 318.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 314.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 313.6
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 312.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 312.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 311.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 311.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 309.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 308.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 307.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 306.6
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 301.2
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 299.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 299.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 294.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 294.6
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 293.5
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 292.1
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 289.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 288.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 286.7
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 284.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 284.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 283.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 280.8
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 278.0
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 274.9
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 273.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 268.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 268.1
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 264.2
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 263.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 263.5
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 261.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 260.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 259.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 257.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 249.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 247.4
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 246.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 245.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 240.4
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 233.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 232.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 232.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 227.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 225.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 222.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 211.7
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 201.4
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 194.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 189.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 178.4
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 139.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 139.2
FF:10158-103A5 76 years, female 139.2

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 0.0
Pig sample Sample description nTPM
Midbrain
nTPM: 0.0
Samples: 4

Max nTPM: 0.0
Min nTPM: 0.0
Sample A Female 0.0
Sample B Female 0.0
Sample C Male 0.0
Sample D Male 0.0
Periaqueductal gray
nTPM: 0.0
Samples: 3

Max nTPM: 0.0
Min nTPM: 0.0
Sample B Female 0.0
Sample C Male 0.0
Sample D Male 0.0
Substantia nigra
nTPM: 0.0
Samples: 4

Max nTPM: 0.0
Min nTPM: 0.0
Sample A Female 0.0
Sample B Female 0.0
Sample C Male 0.0
Sample D Male 0.0
Superior colliculi
nTPM: 0.0
Samples: 4

Max nTPM: 0.0
Min nTPM: 0.0
Sample A Female 0.0
Sample B Female 0.0
Sample C Male 0.0
Sample D Male 0.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 137.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 137.1
Samples: 4

Max nTPM: 151.6
Min nTPM: 123.5
Sample A Male 148.9
Sample B Male 124.2
Sample C Female 123.5
Sample D Female 151.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 4.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.6
69782276 Antisense, RP_050505_02_F07, Mouse strain C57BL/6J (56 days, male) 4.6

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